TCA Tricyclic Antidepresants Test Card
- Known as:
- TCA Tricyclic Antidepresants Test Card
- Catalog number:
- 4s00259
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Good Biotech Corp - GBC
- Gene target:
- TCA Tricyclic Antidepresants Test Card
Related genes to: TCA Tricyclic Antidepresants Test Card
- Gene:
- MAVS NIH gene
- Name:
- mitochondrial antiviral signaling protein
- Previous symbol:
- -
- Synonyms:
- VISA, KIAA1271, IPS-1, Cardif
- Chromosome:
- 20p13
- Locus Type:
- gene with protein product
- Date approved:
- 2009-04-01
- Date modifiied:
- 2017-09-22
Related products to: TCA Tricyclic Antidepresants Test Card
Related articles to: TCA Tricyclic Antidepresants Test Card
- Nowadays, trajectory control is a significant issue for unmanned micro aerial vehicles (MAVs) due to large disturbances such as wind and storms. Trajectory control is typically implemented using a proportional-integral-derivative (PID) controller. In order to achieve high accuracy in trajectory tracking, it is essential to set the PID gain parameters to optimum values. For this reason, separate gain values are set for roll, pitch and yaw movements before autonomous flight in quadrotor systems. Traditionally, this adjustment is performed manually or automatically in autotune mode. Given the constraints of narrow orchard corridors, the use of manual or autotune mode is neither practical nor effective, as the quadrotor system has to fly in narrow apple orchard corridors covered with hail nets. These reasons require the development of an innovative solution specific to quadrotor vehicles designed for constrained areas such as apple orchards. This paper recognizes the need for effective trajectory control in quadrotors and proposes a novel neural network-based approach to tuning the optimal PID control parameters. This new approach not only improves trajectory control efficiency but also addresses the unique challenges posed by environments with constrained locational characteristics. Flight simulations using the proposed neural network models have demonstrated successful trajectory tracking performance and highlighted the superiority of the feed-forward back propagation network (FFBPN), especially in latitude tracking within 7.52745 × 10 RMSE trajectory error. Simulation results support the high performance of the proposed approach for the development of automatic flight capabilities in challenging environments. - Source: PubMed
Publication date: 2024/04/26
Ulu BurakSavaş SertaçErgin Ömer FarukUlu BanuKırnap AhmetBingöl Mehmet SafaYıldırım Şahin - [This corrects the article DOI: 10.1371/journal.ppat.1003231.]. - Source: PubMed
Publication date: 2024/05/06
Wang BeiXi XueyanLei XiaoboZhang XiaoyanCui ShengWang JianweiJin QiZhao Zhendong - Ophthalmic manifestations have recently been observed in acute and post-acute complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown that host RNA editing is linked to RNA viral infection, yet ocular adenosine to inosine (A-to-I) RNA editing during SARS-CoV-2 infection remains uninvestigated in COVID-19. Herein we used an epitranscriptomic pipeline to analyze 37 samples and investigate A-to-I editing associated with SARS-CoV-2 infection, in five ocular tissue types including the conjunctiva, limbus, cornea, sclera, and retinal organoids. Our results revealed dramatically altered A-to-I RNA editing across the five ocular tissues. Notably, the transcriptome-wide average level of RNA editing was increased in the cornea but generally decreased in the other four ocular tissues. Functional enrichment analysis showed that differential RNA editing (DRE) was mainly in genes related to ubiquitin-dependent protein catabolic process, transcriptional regulation, and RNA splicing. In addition to tissue-specific RNA editing found in each tissue, common RNA editing was observed across different tissues, especially in the innate antiviral immune gene MAVS and the E3 ubiquitin-protein ligase MDM2. Analysis in retinal organoids further revealed highly dynamic RNA editing alterations over time during SARS-CoV-2 infection. Our study thus suggested the potential role played by RNA editing in ophthalmic manifestations of COVID-19, and highlighted its potential transcriptome impact, especially on innate immunity. - Source: PubMed
Publication date: 2024/05/01
Jin Yun-YunLiang Ya-PingHuang Wen-HaoGuo LiangCheng Li-LiRan Tian-TianYao Jin-PingZhu LinChen Jian-Huan - Current cancer therapies often fall short in addressing the complexities of malignancies, underscoring the urgent need for innovative treatment strategies. RNA interference technology, which specifically suppresses gene expression, offers a promising new approach in the fight against tumors. Recent studies have identified a novel immunostimulatory small-interfering RNA (siRNA) with a unique sequence (sense strand, 5'-C; antisense strand, 3'-GGG) capable of activating the RIG-I/IRF3 signaling pathway. This activation induces the release of type I and III interferons, leading to an effective antiviral immune response. However, this class of immunostimulatory siRNA has not yet been explored in cancer therapy. - Source: PubMed
Publication date: 2024/04/29
Chen JunxiaoLiu ZiyuanFang HaitingSu QingFan YiqiSong LuyaoHe Shuai - The exacerbation of pneumonia in children with human adenovirus type 3 (HAdV-3E) is secondary to a () infection. The influence of host-pathogen interactions on disease progression remains unclear. It is important to note that infections following an HAdV-3E infection are frequently observed in clinical settings, yet the underlying susceptibility mechanisms are not fully understood. This study utilized an A549 cell model to investigate secondary infection with following an HAdV-3E infection. The findings suggest that HAdV-3E exacerbates the infection by intensifying lung epithelial cell damage. The results highlight the role of HAdV-3E in enhancing the interferon signaling pathway through (), resulting in the increased expression of interferon-stimulating factors like , , and . The increase in interferon-stimulating factors inhibits the NF-κB and MAPK/P38 pro-inflammatory signaling pathways. These findings reveal new mechanisms of action for HAdV-3E and in secondary infections, enhancing our comprehension of pathogenesis. - Source: PubMed
Publication date: 2024/04/10
Chen JiehanWang QiaowenZhong BiyingZheng HuiyingWang DingjunHuang XiaoLiu LiLiu Tiantian