RICH2 Antibody (C-term) Blocking Peptide
- Known as:
- RICH2 Antibody (C-terminus) Blocking Peptide
- Catalog number:
- BP10656b
- Product Quantity:
- 0.1 mg
- Category:
- -
- Supplier:
- Abgen
- Gene target:
- RICH2 Antibody (C-term) Blocking Peptide
Ask about this productRelated genes to: RICH2 Antibody (C-term) Blocking Peptide
- Gene:
- ARHGAP44 NIH gene
- Name:
- Rho GTPase activating protein 44
- Previous symbol:
- -
- Synonyms:
- KIAA0672, RICH-2, RICH2
- Chromosome:
- 17p12
- Locus Type:
- gene with protein product
- Date approved:
- 2010-08-19
- Date modifiied:
- 2015-08-26
Related products to: RICH2 Antibody (C-term) Blocking Peptide
Related articles to: RICH2 Antibody (C-term) Blocking Peptide
- - Source: PubMed
Publication date: 2023/12/18
Li ShizheXue JianchengZhang HeShang Guanning - Osteosarcoma is a rare primary malignant tumor of the bone characterized by poor survival rates, owing to its unclear pathogenesis. Rho GTPase-activating protein 44 (ARHGAP44), which belongs to the Rho GTPase-activating protein family, has promising applications in the targeted therapy of tumors. Therefore, this study aimed to investigate the biological function of ARHGAP44 in osteosarcoma and its possible application as a therapeutic target. - Source: PubMed
Publication date: 2023/11/29
Li ShizheXue JianchengZhang HeShang Guanning - Deep learning techniques are gaining momentum in medical research. Colorectal adenoma (CRA) is a precancerous lesion that may develop into colorectal cancer (CRC) and its etiology and pathogenesis are unclear. This study aims to identify transcriptome differences between CRA and CRC via deep learning on Gene Expression Omnibus (GEO) databases and bioinformatics in the Chinese population. - Source: PubMed
Publication date: 2023/02/05
Zhang XinJin MingxinLiu FengjunQu HuiChen Cheng - Loin muscle area (LMA) is an important target trait of pig breeding. This study aimed to identify single nucleotide polymorphisms (SNPs) and genes associated with LMA in the DurocĂ—(LandraceĂ—Yorkshire) crossbred pigs (DLY). - Source: PubMed
Publication date: 2023/01/11
Luan MenghaoRuan DonglinQiu YibinYe YongZhou ShenpingYang JifeiSun YingMa FucaiWu ZhenfangYang JieYang MingZheng EnqinCai GengyuanHuang Sixiu - Rho family small GTPases, such as Rho, Rac, and Cdc42, play essential roles during brain development, by regulating cellular signaling and actin cytoskeletal reorganization. Rich2/Arhgap44, a Rac- and Cdc42-specific GTPase-activating protein, has been reported to be a key regulator for dendritic spine morphology and synaptic function. Given the essential roles of Rac and Cdc42 in brain development, Rich2 is supposed to take part in brain development. However, not only the molecular mechanism involved but also the expression profile of Rich2 during neurodevelopment has not yet been elucidated. In this study, we carried out expression analyses of Rich2 by focusing on mouse brain development. In immunoblotting, Rich2 exhibited a tissue-dependent expression profile in the young adult mouse, and the expression was increased during brain development. In immunohistochemical analyses, Rich2 was observed in the cytoplasm of cortical neurons at postnatal day (P) 0 and then came to be enriched in the nucleus with moderate distribution in neuropils at P7. Later at P30, a complex immunostaining pattern of Rich2 was observed; Rich2 was distributed in the nucleus, cytoplasm, and neuropils in many cortical neurons, whereas other neurons frequently displayed little expression. In the hippocampus at P7, Rich2 was distributed mainly in the cytoplasm of excitatory neurons in the cornu ammonis regions, while it was moderately detected in the nucleus in the dentate granule cells. Notably, Rich2 was distributed in excitatory synapses of the cornu ammonis 1 region at P30. Biochemical fractionation analyses also detected Rich2 in the postsynaptic density. Taken together, Rich2 is found to be expressed in the central nervous system in a developmental stage-dependent manner and may be involved in synapse formation/maintenance in cortical neurons. - Source: PubMed
Publication date: 2023/01/11
Goto NaokiNishikawa MasashiIto HidenoriNoda MarikoHamada NanakoTabata HidenoriKinoshita MakotoNagata Koh-Ichi