12ML TUBE, DUAL CAP, POLYPROPYLENE,50_BAG,STERILE
- Known as:
- 12ML TUBE, DUAL CAP, POLYPROPYLENE,50_BAG,STERILE
- Catalog number:
- TD444-S
- Product Quantity:
- 1PK
- Category:
- -
- Supplier:
- BioBasic
- Gene target:
- 12ML TUBE DUAL CAP POLYPROPYLENE 50_BAG STERILE
Related genes to: 12ML TUBE, DUAL CAP, POLYPROPYLENE,50_BAG,STERILE
- Gene:
- TUBE1 NIH gene
- Name:
- tubulin epsilon 1
- Previous symbol:
- -
- Synonyms:
- dJ142L7.2, FLJ22589, TUBE
- Chromosome:
- 6q21
- Locus Type:
- gene with protein product
- Date approved:
- 2003-05-22
- Date modifiied:
- 2015-12-17
Related products to: 12ML TUBE, DUAL CAP, POLYPROPYLENE,50_BAG,STERILE
Related articles to: 12ML TUBE, DUAL CAP, POLYPROPYLENE,50_BAG,STERILE
- Rectal cancer (RC) is one of the most common malignant tumors. Ferroptosis is an iron-dependent form of cell death, which plays an important role in various cancers. However, the correlation between ferroptosis-related genes (FRGs) and prognosis in RC remains unclear. - Source: PubMed
Publication date: 2022/11/22
Shi Wei-KunLiu Yu-XinQiu Xiao-YuanZhou Jing-YaZhou Jiao-LinLin Guo-Le - Ferroptosis plays a crucial role in the initiation and progression of melanoma. This study developed a robust signature with ferroptosis-related genes (FRGs) and assessed the ability of this signature to predict OS in patients with skin cutaneous melanoma (SKCM). - Source: PubMed
Publication date: 2022/04/04
Ping ShuaiWang SiyuanZhao YingsongHe JinbingLi GuangleiLi DinglinWei ZhuoChen Jianghai - Bladder exstrophy (BE) is a rare, lower ventral midline defect with the bladder and part of the urethra exposed. The etiology of BE is unknown but thought to be influenced by genetic variation with more recent studies suggesting a role for rare variants. As such, we conducted paired-end exome sequencing in 26 child/mother/father trios. Three children had rare (allele frequency ≤ 0.0001 in several public databases) inherited variants in TSPAN4, one with a loss-of-function variant and two with missense variants. Two children had loss-of-function variants in TUBE1. Four children had rare missense or nonsense variants (one per child) in WNT3, CRKL, MYH9, or LZTR1, genes previously associated with BE. We detected 17 de novo missense variants in 13 children and three de novo loss-of-function variants (AKR1C2, PRRX1, PPM1D) in three children (one per child). We also detected rare compound heterozygous loss-of-function variants in PLCH2 and CLEC4M and rare inherited missense or loss-of-function variants in additional genes applying autosomal recessive (three genes) and X-linked recessive inheritance models (13 genes). Variants in two genes identified may implicate disruption in cell migration (TUBE1) and adhesion (TSPAN4) processes, mechanisms proposed for BE, and provide additional evidence for rare variants in the development of this defect. - Source: PubMed
Publication date: 2021/08/05
Pitsava GeorgiaFeldkamp Marcia LPankratz NathanLane JohnKay Denise MConway Kristin MShaw Gary MReefhuis JennitaJenkins Mary MAlmli Lynn MOlshan Andrew FPangilinan FaithBrody Lawrence CSicko Robert JHobbs Charlotte ABamshad MikeMcGoldrick DanielNickerson Deborah AFinnell Richard HMullikin JamesRomitti Paul AMills James L - Centrosomes are essential organelles with functions in microtubule organization that duplicate once per cell cycle. The first step of centrosome duplication is the daughter centriole formation followed by the pericentriolar material recruitment to this centriole. This maturation step was termed centriole-to-centrosome conversion. It was proposed that CEP295-dependent recruitment of pericentriolar proteins drives centriole conversion. Here we show, based on the analysis of proteins that promote centriole biogenesis, that the developing centriole structure helps drive centriole conversion. Depletion of the luminal centriole protein CEP44 that binds to the A-microtubules and interacts with POC1B affecting centriole structure and centriole conversion, despite CEP295 binding to centrioles. Impairment of POC1B, TUBE1 or TUBD1, which disturbs integrity of centriole microtubules, also prevents centriole-to-centrosome conversion. We propose that the CEP295, CEP44, POC1B, TUBE1 and TUBD1 centriole biogenesis pathway that functions in the centriole lumen and on the cytoplasmic side is essential for the centriole-to-centrosome conversion. - Source: PubMed
Publication date: 2020/02/14
Atorino Enrico SHata ShojiFunaya CharlottaNeuner AnnettSchiebel Elmar - Interstitial 6q deletions, involving the 6q15q25 chromosomal region, are rare events characterized by variable phenotypes and no clear karyotype/phenotype correlation has been determined yet. - Source: PubMed
Publication date: 2015/04/28
Tassano ElisaMirabelli-Badenier MarisolVeneselli EdvigePuliti AldamariaLerone MargheritaVaccari Carlotta MariaMorana GiovanniPorta SimonaGimelli GiorgioCuoco Cristina