CD95 _ FAS (C_term)
- Known as:
- CD95 _ Fas Cell Surface Death Receptor (C_term)
- Catalog number:
- AP15456PU-N
- Product Quantity:
- 1.0 ml
- Category:
- -
- Supplier:
- ACR
- Gene target:
- CD95 _ FAS (C_term)
Related genes to: CD95 _ FAS (C_term)
- Gene:
- FAS NIH gene
- Name:
- Fas cell surface death receptor
- Previous symbol:
- FAS1, APT1, TNFRSF6
- Synonyms:
- CD95, APO-1
- Chromosome:
- 10q23.31
- Locus Type:
- gene with protein product
- Date approved:
- 1992-06-25
- Date modifiied:
- 2019-04-23
Related products to: CD95 _ FAS (C_term)
Related articles to: CD95 _ FAS (C_term)
- Placenta-mediated diseases, such as preeclampsia (PE) and small-for-gestational-age (SGA) neonates, are associated with structural and functional changes in the placenta. While ultrasound is routinely performed during pregnancy, its potential for detecting such diseases using deep learning remains underexplored. This study presents a deep transfer learning approach using Convolutional Neural Networks (CNNs) to detect placenta-mediated diseases from ultrasound B-mode images of the human placenta ex vivo. This study is a secondary analysis of data from a prospective case-control study, where placentas were collected from women who delivered at BC Women's Hospital, Vancouver, Canada, from April 2018 to April 2020. Ultrasound data obtained from ex vivo human placentas were used to perform transfer learning using three deep learning architectures: DenseNet-121, ResNet-50, and InceptionV3, each pretrained on one of two datasets: ImageNet or RadImageNet, to detect SGA and/or PE outcome. The dataset consisted of 46 placentas obtained from 40 participants, of which 25 placentas were complicated by SGA and/or PE (including 12 SGA-only placentas, 2 PE placentas, and 11 placentas affected by both SGA and PE). Experimental results demonstrate that DenseNet-121, when pretrained with ImageNet, achieved the most promising performance, with accuracy of 0.76 ± 0.12, F1-score of 0.78 ± 0.09, and area under the receiver operating characteristic curve (AUC) of 0.86 ± 0.10. Among the RadImageNet pretrained models, ResNet-50 yielded an accuracy 0.75 ± 0.10, F1-score 0.77 ± 0.07, and AUC of 0.84 ± 0.09. Our proof-of-concept results demonstrate that standard B-mode ultrasound images of the placenta ex vivo contain sufficient information to distinguish between normal pregnancies and pregnancies affected by SGA and PE. - Source: PubMed
Publication date: 2026/06/25
Jim Salman JubairLotfian SinaAlam Minhaj NurRohling RobertDeeba Farah - This study aimed to evaluate the efficacy and safety of OsteoKing compared to a standard active comparator (Yaobitong capsules) for managing lumbar disc herniation (LDH). - Source: PubMed
Publication date: 2026/06/25
Wu ZhuoyunDong ShiyuMa HongqingMa YufengZhang KuayueWang XuehuiWang HaoDu ShuangqingWu WenjieFan TaoWei JianWang WengeHan YueMa ChaoCheng FuhongPang YuanSun RongxinZhu ZiqiangChen LinlinFang WeiLiu XiangrongQing PeidongMi BaohongChen Weiheng - Canned fish products enable long-term preservation of fish, a vital source of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Despite research on lipid composition, gaps remain in understanding the bidirectional fatty acid (FA) exchange between fish muscle and coating media during processing and storage. After a systematic literature search across five databases (PubMed, Scopus, Web of Science, Wiley Online Library, Cochrane Library), 20 studies were included examining FA profiles across fish species, filling media (vegetable oils, brine, tomato sauce), and storage durations (up to 5 years). Five studies showed that n-3 FAs migrate from fish to the filling medium, enhancing its nutritional value, while fish muscle absorbs FAs from the oil, increasingly resembling the filling medium. The use of n-6 FA-rich oils (sunflower, soybean) lowered the n-3/n-6 ratio in flesh. Conversely, aqueous media (brine) and tomato sauce maintained better ratios. EPA and DHA content generally decreased due to canning and storage, with retention varying by fish species, filling medium, and sterilization method. This review underscores significant FA exchange between fish and filling media, confirming bidirectional lipid interchange during processing. To optimize health benefits, aqueous packing media are recommended to preserve lipid profiles or to consume the covering oil to recover nutrients. Further research is needed on other factors altering FA content in canned fish such as environmental and geographical variables (including catching season), pre-canning preparation and sterilization steps (such as freezing, steaming, and frying), sterilization conditions (time, temperature, F value) and lipid oxidation induced by thermal processing. - Source: PubMed
Publication date: 2026/06/10
Kaçar Ömer FurkanHatem OkbaKaçar Hüsna KayaSzabó Éva - Isokinetic strength of the knee joint represents a significant determinant of athletic performance and injury prevention; however, its relationship with explosive performance in young female athletes remains insufficiently explored. The aim of the study was to analyze the relationships between isokinetic strength of the knee joint at different angular velocities and explosive jumping performance in young female athletes. The research sample consisted of 13 young female athletes enrolled in sport-oriented educational programs specializing in athletics. Explosive lower-limb power was assessed using performance tests for countermovement jump (CMJ), countermovement jump free arms (CMJ FAs) and squat jump (SJ) administered with the Chronojump system. Isokinetic strength of the knee flexors and extensors was assessed using the Humac Norm dynamometer in the concentric mode at angular velocities of 60°/s, 180°/s, and 300°/s. Peak torque, the ipsilateral H:Q ratio, and bilateral asymmetries were evaluated. Pearson's correlation coefficient was used to analyze the relationships between the investigated parameters. The strongest relationships with explosive performance were observed for hamstring strength at an angular velocity of 180°/s, where significant high correlations were identified with performance in the CMJ (r = 0.693), CMJ FA (r = 0.754), and SJ (r = 0.713). In contrast, quadriceps strength demonstrated predominantly low to moderate associations with jumping performance, while no significant correlations were confirmed at an angular velocity of 300°/s. Bilateral asymmetries of the knee extensors and flexors were generally low, ranging approximately between 7 and 10%, whereas the values of the ipsilateral H:Q ratio were within the physiological range of approximately 50-55%. The results suggest that the ability to generate force at higher contraction velocities, particularly in the hamstrings, is significantly associated with explosive performance in young female athletes. At the same time, isokinetic strength assessment appears to be an appropriate tool for evaluating muscular strength, muscle balance, and potential asymmetries in youth sports. However, explosive performance cannot be explained solely by the level of maximal muscular strength, but rather by a complex interaction of neuromuscular and biomechanical factors. - Source: PubMed
Publication date: 2026/06/13
Falat Leütterová DanielaSučka Jaroslav - : Dietary protein optimization is an important nutritional strategy for improving growth and physiological responses, and antioxidant homeostasis in fish. : In this study, 540 black carp (initial body weight: 10.50 ± 1.00 g) were randomly assigned into recirculating tanks (500 L) fed with six dietary protein levels (30-44% crude protein) for an 8-week feeding trial with triplicates per treatment and 30 fish per replicate. After the trial, fish body, blood, hepatopancreas, and intestinal samples were collected for body composition, serum biochemical parameters, metabolism, and antioxidant indices' analyses. : Results showed fish fed 38% protein (PT38) exhibited the highest weight gain ( < 0.05), with no further improvement at higher protein levels. Compared with PT30 group, PT38 group significantly promoted protein deposition by upregulating transcript levels of insulin-like growth factors () via activating mechanistic target of rapamycin () signaling pathway. PT38 could improve fatty acid oxidation by heightening levels of carnitine palmitoyl transferase 1α (), peroxisome proliferator-activated receptor α () and . Meanwhile, PT38-PT41 significantly inhibit expression of fatty acid synthesis and lipid droplet deposition-related genes, including acetyl-CoA carboxylase (), fatty acid synthase (), and perilipin 2 ( < 0.05). PT38 significantly enhanced antioxidant homeostasis by increasing levels of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) via activating nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. : Overall, Under the current experimental conditions, 38% dietary protein is suitable for promoting growth performance, improving protein and lipid metabolism, and enhancing antioxidant homeostasis in black carp. - Source: PubMed
Publication date: 2026/06/04
Zhang JinjingYang SongtingZhu YukaiYu JiaxingZhang YuanyuanLi JieLin ChengyeWu Chenglong