CD95 _ FAS
- Known as:
- CD95 _ Fas Cell Surface Death Receptor
- Catalog number:
- AM08165BT-N
- Product Quantity:
- 100 Tests
- Category:
- -
- Supplier:
- ACR
- Gene target:
- CD95 _ FAS
Related genes to: CD95 _ FAS
- Gene:
- FAS NIH gene
- Name:
- Fas cell surface death receptor
- Previous symbol:
- FAS1, APT1, TNFRSF6
- Synonyms:
- CD95, APO-1
- Chromosome:
- 10q23.31
- Locus Type:
- gene with protein product
- Date approved:
- 1992-06-25
- Date modifiied:
- 2019-04-23
Related products to: CD95 _ FAS
Related articles to: CD95 _ FAS
- The use of immune checkpoint inhibitors (ICIs) is expanding in the treatment of a variety of cancer types; however, treatment with ICIs may result in off-target kidney inflammation in 3-5% of patients, most commonly acute interstitial nephritis (AIN). There is a significant unmet need for noninvasive diagnostic tools to facilitate accurate and timely diagnosis, and for targeted therapeutic strategies to more specifically block inflammation in ICI-AIN. - Source: PubMed
Publication date: 2026/07/17
Mistry KavitaBest RoyaStueber Christopher TSise Meghan E - This study evaluated the utility of the Controlled Oral Word Association Test (COWAT-FAS) and Animal Naming as embedded performance validity tests (PVTs) in a mixed clinical sample of 165 military veterans referred for neuropsychological evaluation. Participants had either a self-reported history of mild TBI or were referred for evaluation of possible ADHD. Participants were classified as credible (0 PVT failures; = 92) or non-credible (≥2 PVT failures; = 73). Classification accuracy was examined for COWAT and Animal Naming raw scores, demographically adjusted T-scores, and two previously published logistic regression models. Both verbal fluency measures significantly differentiated credible from non-credible groups. Optimal indices utilized COWAT raw scores, either alone or when embedded within the logistic regression formula. Findings support verbal fluency measures as efficient embedded, non-memory-based PVTs. - Source: PubMed
Publication date: 2026/07/18
Johnson KeithAshendorf Lee - This study presents updated regression-based norms for verbal fluency tests: "FAS," "Animals," and "Supermarket" in older Norwegian adults. By examining the potential modulating effects and putative interaction effects of age, education, and sex, we aim to investigate cognitive aging and the effects of education. - Source: PubMed
Publication date: 2026/07/18
Waggestad Therese HändelKirsebom Bjørn-EivindStrobel CarstenGjøra LindaSelbæk GeirBekkhus-Wetterberg PeterEgeland Jens - Timely follow-up and removal of inferior vena cava (IVC) filters is important for preventing filter-related complications. This study evaluated the performance and clinical impact of integrating the Filter Alert System (FAS), a natural language processing tool for identifying patients with an inferior vena cava (IVC) filter. - Source: PubMed
Publication date: 2026/07/13
Hardy JosiahAhmed OmarMalinow IanParsa ShirinLim MariaHerskovits EdwardKim HyunFang Adam - As the cheapest feed ingredient, carbohydrates exert a protein-sparing effect. However, excessive carbohydrate intake can induce hepatic metabolic disorders and lead to metabolic diseases in fish. The GIP/GIPR axis plays a vital role in regulating lipid metabolism and glucose uptake. To evaluate the functions of GIP and GIPR in largemouth bass, we cloned their cDNA sequences. We analysed the tissue-specific expression of both genes and assessed the role of GIP in regulating glucose and lipid metabolism using hepatocyte studies and GIP interference assays. The largemouth bass gip gene (318 bp) encodes a protein of 105 amino acids, whereas the gipr gene (1614 bp) encodes a protein of 537 amino acids. Tissue distribution analysis revealed high expression of gip mRNA in the stomach. Additionally, gipr mRNA was highly expressed in the brain, foregut, midgut and hindgut. Both high-carbohydrate and high-fat intake in largemouth bass resulted in higher gip mRNA in the stomach and lower gipr mRNA expression in the foregut. Primary hepatocyte experiments showed that GIP treatment increased the expression of g6pase, acc1 and fas and decreased the expression of gk, pfk, hsl and lpl. Intraperitoneal injection of GIP small interfering RNA (siRNA) demonstrated that inhibiting GIP expression significantly reduced serum glucose and triglyceride levels. It also decreased the hepatic expression of g6pase, fbp1, pygl, acc1, fas and lpl, while increasing the expression of gys2 and hsl. These results suggest that GIP and GIPR regulate glucose and lipid metabolism in largemouth bass. - Source: PubMed
Publication date: 2026/07/18
Yin MingyueGuo ShihuiGu JianingZhang YingYang LiliZhang YanminZhang XindangChang XuluFeng ShikunNaiel Mohammed A EYang GuokunMeng Xiaolin