GSTK1, 1_226aa, Human, E.coli
- Known as:
- GSTK1, 1_226aa, Human, E.coli
- Catalog number:
- ATGP0464
- Product Quantity:
- 0.5mg
- Category:
- -
- Supplier:
- ATGen
- Gene target:
- GSTK1 1_226aa Human .coli
Related genes to: GSTK1, 1_226aa, Human, E.coli
- Gene:
- FCN2 NIH gene
- Name:
- ficolin 2
- Previous symbol:
- -
- Synonyms:
- P35, FCNL, EBP-37, ficolin-2
- Chromosome:
- 9q34.3
- Locus Type:
- gene with protein product
- Date approved:
- 1996-07-11
- Date modifiied:
- 2016-10-05
- Gene:
- GSTK1 NIH gene
- Name:
- glutathione S-transferase kappa 1
- Previous symbol:
- -
- Synonyms:
- GST13
- Chromosome:
- 7q34
- Locus Type:
- gene with protein product
- Date approved:
- 2004-10-22
- Date modifiied:
- 2014-11-19
Related products to: GSTK1, 1_226aa, Human, E.coli
Related articles to: GSTK1, 1_226aa, Human, E.coli
- Disulfidptosis is a recently discovered mechanism of cell death caused by disulfide stress. Arachidonic acid metabolism (AAM) is one of the metabolic mechanisms of polyunsaturated fatty acids. However, few studies have explored the relationship between disulfidptosis and AAM and how together they affect breast cancer prognosis. The aim of this study was to establish a prognostic model of disulfidptosis and arachidonic acid metabolism in breast cancer and to investigate the potential mechanisms of disulfidptosis and arachidonic acid in breast cancer. - Source: PubMed
Publication date: 2026/05/07
Yan TaoYu BolinQian FengyuanFang LinZhao YuanyuanYe Danrong - The kappa class of glutathione S-transferases 1 (GSTK1) is a vital regulatory factor in metabolic diseases. This study was conducted to investigate the regulatory effects of GSTK1 on renal ectopic fat deposition (EFD) and lipotoxic injury in diabetic nephropathy (DN) . - Source: PubMed
Publication date: 2026/04/30
Chen HongLiu YanZhao Ming-GeWu Xue-QinDai Ai-MingWang YuYang Ye-YiLi Ai-MeiZhang WeiWang Jun-PuZhou Zhi-JiaoTi-Chen Zhang HaoYang Shikun - Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic liver disorder associated with substantial fetal morbidity, including preterm birth, fetal distress, and even intrauterine demise. Although prior studies have documented structural and transcriptional alterations in the placenta during ICP, the mechanistic underpinnings linking maternal cholestasis to adverse fetal outcomes remain incompletely elucidated. - Source: PubMed
Publication date: 2026/03/20
Xue ZhenhuaHan QiHan HuigangYan LaiqingMa XiaoJi PengyunWang BingyuanZhang LuWang LikaiLiu Guoshi - Glutathione S-transferase kappa 1 (Gstk1) is known to be involved in antioxidant defense and mitochondrial function, yet its role in sepsis-induced myocardial injury (SMI) remains largely unexplored. This study aims to investigate the potential protective role of Gstk1 in LPS-induced myocardial injury and to elucidate its underlying mechanisms. - Source: PubMed
Publication date: 2026/01/18
Gao MinXu ChanghaoSu ZhenyangKong XiangqingXu Tianhua - Polycystic ovary syndrome (PCOS) and atherosclerosis (AS) are interrelated, with studies emphasizing the crucial role of mitochondrial dysfunction in the pathogenesis of both diseases. Therefore, this study utilized bioinformatics analysis to identify key mitochondria-related genes (MitoRGs) and shared mechanisms underlying PCOS and AS. PCOS, AS, and MitoRGs data were obtained from the Gene Expression Omnibus and MitoCarta3.0 databases. The "SVA" and "Limma" packages in R were used to eliminate batch effects and identify differentially expressed genes (DEGs) in PCOS and AS. Shared MitoRGs were identified by intersecting the DEGs between PCOS and AS with mitochondria-related DEGs (MitoDEGs). Least absolute shrinkage and selection operator regression was applied to identify key MitoRGs, which were validated using 2 independent Gene Expression Omnibus datasets to assess their expression levels and diagnostic value. Furthermore, the cell-type identification by estimating relative subsets of RNA transcripts algorithm was used to analyze the correlation between key MitoRGs and immune cells. Our study identified 2306 DEGs in PCOS, 7830 in AS, and 1136 MitoRGs. At the intersection, 66 shared MitoDEGs were identified. These shared MitoDEGs were primarily involved in pathways, such as carbohydrate metabolism and cellular processes. Least absolute shrinkage and selection operator regression and external validation highlighted glutathione S-transferase kappa 1 (GSTK1) as the key MitoRG shared between PCOS and AS. Immune infiltration analysis indicated that GSTK1 was associated with the immune microenvironment in both PCOS and AS. The mitochondrial gene GSTK1 may be a potential biomarker and therapeutic target for PCOS and AS comorbidity. This study provides insights into their shared pathogenesis and early diagnosis. - Source: PubMed
Tang LiLong WeifangChen QingChen JuanZhang YuqiangNie ZhigangLi Weiqing