Polyclonal Rabbit COX6C Antibody
- Known as:
- Polyclonal Rabbit COX6C Antibody
- Catalog number:
- KA0877
- Product Quantity:
- 100ul
- Category:
- -
- Supplier:
- KareBay
- Gene target:
- Polyclonal Rabbit COX6C Antibody
Related genes to: Polyclonal Rabbit COX6C Antibody
- Gene:
- COX6C NIH gene
- Name:
- cytochrome c oxidase subunit 6C
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 8q22.2
- Locus Type:
- gene with protein product
- Date approved:
- 1989-05-08
- Date modifiied:
- 2016-02-11
Related products to: Polyclonal Rabbit COX6C Antibody
Related articles to: Polyclonal Rabbit COX6C Antibody
- Coronary artery disease (CAD) causes irreversible myocardial dysfunction and progressive heart failure due to loss of contractile function and limited endogenous regenerative capacity. Current therapeutic strategies fail to restore lost myocardium or regenerate damaged cardiac tissue. Identifying dysregulated contractility-related genes may reveal actionable targets for stem cell engineering, iPSC-derived cardiomyocyte design, and tissue regeneration aimed at restoring myocardial contractility and function. - Source: PubMed
Publication date: 2026/03/31
Qu FangzhouAn XifengLei YaqiLu ChongLiu HanxiuMa HuayanLi Yongle - Reliable detection of robust biomarkers from high-dimensional transcriptomic data remains a major challenge in computational oncology. Traditional approaches often suffer from overfitting and poor generalization due to the high dimensionality of genomic data and limited sample sizes. This study aims to identify an optimal, biologically meaningful subset of mRNA biomarkers capable of distinguishing ovarian cancer samples from healthy controls using an integrated machine learning-based feature selection framework. - Source: PubMed
Publication date: 2026/01/28
Thelagathoti Rama KrishnaJiang ChaoChandel Dinesh STom Wesley ASarmiento CleoKrzyzanowski GaryOlou AppolinaireFernando M Rohan - Endometrial Cancer (EC) is one of the most prevalent malignancies in the female reproductive system. Hypoxia is a hallmark of the tumor microenvironment that drives metabolic reprogramming, endoplasmic reticulum (ER) stress, and aggressive behavior in cancer cells. However, the underlying mechanisms remain incompletely understood. This study aimed to investigate hypoxia-mediated regulation of EC progression, focusing on the role of SLC9A7 (Solute Carrier Family 9 Member A7, NHE7). - Source: PubMed
Publication date: 2026/01/23
Yang ShizhouWu TingtingCao ZhuChen ZhengyunMa YuejiangWang TingQian LinhuaHuang Xiufeng - To investigate the effect of on the proliferation of multiple myeloma (MM) cells and its mechanism of action. - Source: PubMed
Li Zhi-HuaWang Yi-HuaLiu Wen-HuaCui Qian-QianMa Yan-Ping - The aim of this study was to clarify the significance of DNA methylation alterations in the histological and clinicopathological diversity of pleomorphic carcinoma of the lung. Eleven samples of non-cancerous lung tissue (N), and 10 and 11 samples of non-sarcomatoid and sarcomatoid components of cancerous tissue (T), respectively, were microdissected from formalin-fixed paraffin-embedded specimens of 11 patients with pleomorphic carcinoma of the lung. Genome-wide DNA methylation analysis was performed on all 32 microdissected tissue samples using the Infinium MethylationEPIC BeadChip. Principal component analysis revealed that DNA methylation alterations are associated with lung carcinogenesis and that the diversity of DNA methylation profiles may increase during transition of the non-sarcomatoid component to the sarcomatoid component. Genes showing differences in DNA methylation level between 11 N samples and all 21 T samples regardless of whether they were non-sarcomatoid or sarcomatoid, and whose transcription levels are potentially regulated by DNA methylation, were accumulated in the cadherin, Wnt and angiogenesis pathways. Significant differences in DNA methylation level between non-sarcomatoid and sarcomatoid components potentially resulting in transcription alterations were observed in the OCIAD2, LAMB1 and DKK3 genes. Sarcomatoid component-specific DNA hypomethylation relative to N samples of C2orf27A and COX6C was correlated with clinicopathological parameters such as lymph vessel invasion and higher pathological stage, respectively. Sarcomatoid component-specific DNA hypomethylation of TSKU, PLAU, PLEKHG4, RPSAP52, XBP1 and TRIM2 was correlated with both recurrence-free and overall survival. These data suggest that the DNA methylation alterations associated with sarcomatoid change may participate in malignant progression and determine patient outcome. - Source: PubMed
Publication date: 2025/12/05
Nakagomi TakahiroFujimoto MaoKuriyama ShojiHishida TomoyukiAsamura HisaoAsakura KeisukeKanai YaeArai Eri