ANGPTL7 antibody Ab host: Rabbit
- Known as:
- ANGPTL7 (anti-) Antibody production species: Rabbit
- Catalog number:
- 'C14484-2
- Product Quantity:
- 0.1 mg
- Category:
- -
- Supplier:
- ACR
- Gene target:
- ANGPTL7 antibody host: Rabbit
Related genes to: ANGPTL7 antibody Ab host: Rabbit
- Gene:
- ANGPTL7 NIH gene
- Name:
- angiopoietin like 7
- Previous symbol:
- -
- Synonyms:
- CDT6, AngX
- Chromosome:
- 1p36.22
- Locus Type:
- gene with protein product
- Date approved:
- 2005-01-07
- Date modifiied:
- 2016-10-05
- Gene:
- PPP1R18 NIH gene
- Name:
- protein phosphatase 1 regulatory subunit 18
- Previous symbol:
- KIAA1949
- Synonyms:
- phostensin
- Chromosome:
- 6p21.33
- Locus Type:
- gene with protein product
- Date approved:
- 2004-03-02
- Date modifiied:
- 2016-10-05
Related products to: ANGPTL7 antibody Ab host: Rabbit
Related articles to: ANGPTL7 antibody Ab host: Rabbit
- Posttransplant diabetes mellitus is a chronic metabolic complication that often develops in kidney transplant recipients and is an inflammatory disease that directly affects a patient's immune system. Angiopoietin and angiopoietin -like proteins are intrinsic mediators of immune cells. We assessed the relationship between circulating angiopoietin proteins ANGPT ¹ and ANGPT ²and angiopoietin-like proteins ANGPTL ³, ANGPTL ⁴, ANGPTL ⁶, ANGPTL ⁷, and ANGPTL ⁸ in kidney transplant recipients who develop posttransplant diabetes mellitus (experimental group) versus recipients who do not develop diabetes after transplant (control group). - Source: PubMed
Jahromi MohamedAl-Otaibi TorkiOthman NashwaMahmoud TarekNair ParasadA-Halim MedhatJahrami KawtharGheith Osama - Osteoarthritis (OA) involves cartilage degradation and subchondral bone alterations, yet the mechanisms of chondro-endothelial crosstalk remain unclear. Stress-sensitive Piezo1 and SP1/Angptl7 signaling may play key roles in this process. This research aimed to investigate whether Platelet-derived growth factor (PDGF)-BB regulates chondro-endothelial crosstalk via Piezo1-mediated SP1/Angptl7 inhibition. - Source: PubMed
Publication date: 2026/07/15
Wang ZhengchaoCheng JiangxiaLi HongmeiZhang QingsongZhu PengfeiCai Yu - Osteoporosis (OP) poses a significant health burden. Circulating proteins represent promising drug targets. However, previous Mendelian randomization (MR) studies have limited evidence for their causal role due to single-source protein quantitative trait loci (pQTL) data and lack of systematic, multi-layered validation. - Source: PubMed
Publication date: 2026/07/08
Zhang ZhengchaoHe JiayuLin XueyanZhu YirenHe Wubing - The prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) has been increasing globally, and data indicate that ferroptosis participates in the pathogenesis of MAFLD. Angiopoietin-like protein 7 (ANGPTL7) is a novel secretory glycoprotein that participates in the pathogenesis of many metabolic diseases. However, the role of ANGPTL7 in MAFLD has been poorly investigated. A total of 194 participants were enrolled, including 104 participants with MAFLD (MAFLD) and 90 healthy controls (Cons). Baseline characteristics and serum biochemical parameters were collected. Serum levels of ANGPTL7, inflammatory factors, and ferroptosis-related proteins were measured by enzyme-linked immunosorbent assay (ELISA). Liver biopsy tissues were obtained from six participants with nonalcoholic steatohepatitis and the trimmed liver tissues from five healthy liver transplant donors; H&E, Masson, Perls Prussian blue, and immunohistochemical staining were performed. Compared with healthy Con, BMI, SBP, and DBP were significantly increased, and ALT, AST, TC, TG, LDL-C, GLU, HbA1c, INS, Hcy, and UA levels were all significantly increased, while HDL-C levels were decreased in MAFLD patients (MAFLD vs. Con, p < 0.05 or p < 0.001). Serum levels of ANGPTL7, TNF-α, IL-6, ACSL4, Keap-1, HO-1, and ferritin were significantly increased, while IL-10, GPX4, and Nrf2 levels were decreased in MAFLD patients when compared with the Con group (MAFLD vs. Con, all p < 0.001). Immunohistochemical staining showed that the expression of ANGPTL7, Keap-1, and HO-1 was significantly increased, while Nrf2 expression was significantly decreased in liver tissue from the MAFLD group (MAFLD vs. Con, all p < 0.05). ROC analysis showed that the optimal cut-off value of serum ANGPTL7 for MAFLD was 9.75 ng/mL, suggesting it could serve as a potential biomarker for the diagnosis of MAFLD. ANGPTL7 may participate in the pathogenesis of MAFLD, and serum ANGPTL7 has predictive value for the diagnosis of MAFLD. - Source: PubMed
Bai JingGao QianLiu YanGao MingmingZhou Yaru - Heart failure (HF) is a major cardiovascular complication of type 2 diabetes mellitus (T2DM), yet reliable biomarkers for early risk stratification remain limited. We investigated the prospective association between plasma angiopoietin-like protein 7 (ANGPTL7) and incident HF, and examined the extent to which this relationship is mediated by insulin resistance (IR). - Source: PubMed
Song YanjunChen XinyueChang Zhen'geWang ChunyueZheng ZhihaoLin ZhangyuLi BowenZhu ChenWang XiaoFu RuiDou Kefei