BCAN ELISA kit
- Known as:
- BCAN Enzyme-linked immunosorbent assay test reagent
- Catalog number:
- DL-BCAN-Hu
- Product Quantity:
- 96T
- Category:
- Elisa Kits
- Supplier:
- WDSTD
- Gene target:
- BCAN ELISA kit
Related genes to: BCAN ELISA kit
- Gene:
- BCAN NIH gene
- Name:
- brevican
- Previous symbol:
- -
- Synonyms:
- BEHAB, MGC13038, CSPG7
- Chromosome:
- 1q23.1
- Locus Type:
- gene with protein product
- Date approved:
- 2004-03-01
- Date modifiied:
- 2016-10-05
Related products to: BCAN ELISA kit
Human ELC ELISA KIT 96 TEST
OxiSelect In Vitro ROS/RNS Assay Kit (Green Fluorescence), Trial Size
OxiSelect Methylglyoxal (MG) Competitive ELISA Kit
OxiSelect Methylglyoxal (MG) Competitive ELISA Kit
OxiSelect TBARS Assay Kit (MDA Quantitation), Trial Size
OxiSelect Total Antioxidant Capacity (TAC) Assay Kit, Trial Size
OxiSelect™ In Vitro ROS RNS Assay Kit (Green Fluorescence), Trial Size(1-3)-beta-D-glucan Sandwich ELISA, Double Antibody(1-Kit )11,12-EET DHET Immunoassay Kit(1-Kit )11,12-EET_DHET Immunoassay Kit(1-Kit) 11,12-DHET Immunoassay Kit(1-Kit) 14,15-DHET Human Urine ELISA Kit(1-Kit) 14,15-DHET Hypertension ELISA Kit(1-Kit) 14,15-DHET sEH activity ELISA Kit(1-Kit) 14,15-EET DHET Hypertension ELISA Kit Related articles to: BCAN ELISA kit
- Patients with muscle-invasive bladder cancer (MIBC) have heterogeneous outcomes following transurethral resection of bladder tumor (TURBT). We used a computational histopathology artificial intelligence (CHAI)-based platform to develop and validate a digital image-only MIBC prognostic biomarker. - Source: PubMed
Publication date: 2026/08/10
Lotan YairMargulis VitalyWoldu SolomonAllison DerekKim Joon KyungBukavina LauraChang Sam SKrishna VrishabKaul GauravNeema AkshayZhang HaochenRoyce Trevor JKrishna VisweshJoshi AnirudhKamat Ashish MLi RogerHensley Patrick J - Colorectal cancer (CRC) screening is crucial for early detection, yet the invasiveness of the gold-standard colonoscopy limits compliance. To address the limitation, this study proposes a novel multi-target free DNA methylation model and evaluated its risk stratification performance for CRC in high-risk populations. - Source: PubMed
Publication date: 2026/07/29
Li YingLi ShibaoWang HuiFeng Qian - To examine associations of inherited chromosomally integrated human herpesvirus 6 (iciHHV-6) with incident dementia and mortality, characterize proteomic and metabolomic correlates of carrier status, and evaluate whether these biomarkers relate to dementia and mortality risk. - Source: PubMed
Publication date: 2026/07/20
Beydoun May ASong MinkyoYun ChoaNoren Hooten NicoleWeiss JordanBeydoun Hind ADuggan Michael RWalker Keenan ALauner Lenore JEvans Michele KZonderman Alan B - To evaluate the diagnostic performance and clinicopathologic relevance of a multi-locus circulating tumor DNA methylation assay, in this prospective, single-center, case-control exploratory study, we enrolled 35 patients with colorectal cancer undergoing surgery and 57 healthy controls undergoing screening colonoscopy at the Asan Medical Center, Seoul, Republic of Korea between July 2024 and January 2025. Peripheral blood was collected before surgery or colonoscopy, and circulating tumor DNA methylation was analyzed using a multi-locus panel targeting Septin9, IKZF1, BCAT1, Septin9-2, BCAN, and VAV3. The main outcomes were test accuracy (sensitivity, specificity, and area under the curve [AUC]) and associations between methylation marker positivity and clinicopathologic features. Circulating tumor DNA was positive in 74.3% of the patients and 12.3% of controls, yielding a sensitivity of 74.3%, specificity of 87.7%, and an AUC of 0.837, whereas serum carcinoembryonic antigen exhibited lower sensitivity (25.7%). Sensitivity in stage I disease was limited (36.4%). Circulating tumor DNA-positive tumors were larger (5.7 cm vs. 2.2 cm, < 0.001) and had more advanced T and N stages. The number of positive markers increased with pathologic stage ( = 0.003). Individual marker analysis revealed that BCAT1, Septin9-2, and VAV3 were associated with higher T stage, whereas BCAN positivity was linked to nodal metastasis. The six-marker circulating tumor DNA methylation assay demonstrated acceptable diagnostic accuracy, with multi-locus patterns associated with tumor burden and invasive features. However, sensitivity for early-stage disease was limited. The assay may serve as a complementary tool for screening and risk stratification. - Source: PubMed
Publication date: 2026/06/25
Lee HayoungKang Jae CheolPark In JaKim Gwang-UnHyun HwiMin Na YoungJeon SungwonKim Byoung-Chul - This study investigated whether chronic noise-induced hearing loss (NIHL) alters cognitive performance during acute noise exposure and examined associated microglial changes in the auditory cortex (ACx) and hippocampus (HC). Sprague-Dawley rats were exposed to broadband white noise (2-20 kHz, 115 dB SPL, 3 h per day for 5 days) to induce NIHL. Cognitive function was evaluated using the novel object recognition test and Y-maze test across three conditions: pre-, post-, and post with sound (w/ S)-phases. Microglial activation was assessed via Iba1 immunofluorescence, Sholl analysis, and Iba1-brevican (BCAN) co-localization. Hippocampal neuroinflammation and autophagy were measured using western blotting for ATG5, TNF-α, and IL-6, as well as qRT-PCR for CD68, IRF1, and IL-1β in MACS-isolated microglia. NIHL increased the discrimination index (DI) in the post-phase. However, DI significantly decreased during acute noise exposure, which was accompanied by increased exploration of the familiar object. Iba1 expression was elevated in both ACx and HC after acute noise exposure, with greater upregulation observed in the NIHL w/ S group. Hippocampal microglia in NIHL w/ S displayed enlarged somata and reduced process complexity. In the ACx, Iba1-BCAN co-localization progressively increased. NIHL reduced hippocampal ATG5 and increased TNF-α levels in the NIHL group, while CD68 and IRF1 expression were further elevated in NIHL w/ S microglia. Chronic NIHL induces context-dependent cognitive vulnerability that becomes apparent under acoustic challenge rather than at baseline. Collectively, these results suggest that hippocampal microglial sensitization may underlie the noise-induced cognitive changes associated with chronic hearing loss. - Source: PubMed
Publication date: 2026/07/13
Park BohyeonJeon Jong ChanKim Do EunPark NaHaeKim So Young