AREG ELISA kit
- Known as:
- AREG Enzyme-linked immunosorbent assay test reagent
- Catalog number:
- DL-AREG-Hu
- Product Quantity:
- 96T
- Category:
- Elisa Kits
- Supplier:
- WDSTD
- Gene target:
- AREG ELISA kit
Related genes to: AREG ELISA kit
- Gene:
- AREG NIH gene
- Name:
- amphiregulin
- Previous symbol:
- SDGF, AREGB
- Synonyms:
- -
- Chromosome:
- 4q13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1989-05-19
- Date modifiied:
- 2015-08-24
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- To investigate the effect of specifically regulating histone deacetylase 3 (HDAC3) on the in vitro maturation (IVM) of bovine oocytes and to elucidate the underlying molecular mechanisms. During IVM, COCs were treated with luteinizing hormone (LH) or different concentrations of the HDAC3-specific inhibitor HDACi 4b. Treatment with 4 μM HDACi 4b significantly promoted cumulus expansion and up-regulated the expression of expansion-related genes (HAS2, PTX3, and TNFAIP6) in cumulus cells after IVM (P < 0.05). The first polar body extrusion rate, cleavage rate, and blastocyst rate in the 4 μM HDACi 4b group were comparable to those in the LH group, with normal blastocyst quality. ELISA found no significant difference for the concentration of AREG in the culture medium between the 4 μM HDACi 4b and LH groups, but both were significantly higher than the negative control. Further exploration of the underlying mechanisms in primary granulosa cell line revealed that HDACi 4b inhibited the expression of HDAC3 protein in a time-dependent manner and concurrently up-regulating H3K14ac and AREG levels (P < 0.05). While inhibition of the transcription factor SP1 significantly attenuated the HDACi 4b-induced up-regulation of AREG (P < 0.05). The HDAC3-H3K14ac-SP1-AREG signaling pathway plays a critical regulatory role in the maturation of bovine oocytes. Our work profiles a novel and stable strategy for bovine oocyte IVM. - Source: PubMed
Publication date: 2026/05/15
Hu YingfanHeng NuoGuo YaxinWang YiWang HuanHu ZhihuiZhu HuabinWang ChaoShi LeiZhao Shanjiang - Castration-resistant prostate cancer (CRPC) represents a lethal stage of prostate cancer for which effective therapeutic options remain limited. Aberrant activation of the Hippo pathway effector Yes-associated protein (YAP) and its crosstalk with epidermal growth factor receptor (EGFR) signaling have been implicated in tumor progression, cancer stemness, and metastasis. This study aimed to investigate the therapeutic potential and underlying mechanisms of ATN, a 1,2,4-oxadiazole-based YAP inhibitor, in CRPC cells. - Source: PubMed
Publication date: 2026/05/01
Lin Kuan-JungLiu Jui-MingLin Hsiang-WenWeng Jing-RuDokla Eman M ELu Meng-TienChu Po-Chen - Biological sex influences immune function and inflammatory regulation, but its molecular role in periodontal disease remains insufficiently understood. This pilot study investigated sex-dependent differences in immune gene expression in patients with severe periodontitis. - Source: PubMed
Publication date: 2026/05/14
Dimitrov DDosseva-Panova VDimova INikolova D - Epithelial barrier disruption is a hallmark of allergic skin diseases. Sodium dodecyl sulfate (SDS), a surfactant in household cleaning products, is known to impair the barrier. - Source: PubMed
Publication date: 2026/05/17
Li ManruBabayev HuseynD'Avino PaoloZeyneloğlu CanBicer CerenYazici DuyguPat YagizSvedenhag PerGaudenzio NicolasAkdis Cezmi AMitamura Yasutaka - The first search for the B_{s}^{0}→K^{-}π^{+}γ decay in the range 796Aaij RAbdelmotteleb A S WAbellan Beteta CAbudinén FAckernley TAdefisoye A AAdeva BAdinolfi MAdlarson PAgapopoulou CAidala C AAjaltouni ZAkar SAkiba KAkthar MAlbicocco PAlbrecht JAleksiejunas RAlessio FAlvarez Cartelle PAmalric RAmato SAmey J LAmhis YAn LAnderlini LAndersson MAndreola PAndreotti MAndres Estrada SAnelli AAo DArata CArchilli FAreg ZArgenton MArguedas Cuendis SArnone LArtamonov AArtuso MAslanides EAtaíde Da Silva RAtzeni MAudurier BAuthier J ABacher DBachiller Perea IBachmann SBachmayer MBack J JBaladron Rodriguez PBalagura VBalboni ABaldini WBaldwin ZBalzani LBao HBaptista de Souza Leite JBarbero Pretel CBarbetti MBarbosa I RBarlow R JBarnyakov MBarsuk SBarter WBartz JBashir SBatsukh BBattista P BBavarchee ABay ABeck ABecker MBedeschi FBediaga I BBehling N ABelin SBellavista ABelous KBelov IBelyaev IBenane GBencivenni GBen-Haim EBerezhnoy ABernet RBernet Andres SBertolin ABetti FBex JBezshyyko OBhattacharya SBieker M SBiesuz N VBiolchini ABirch MBishop F C RBitadze ABizzeti ABlake TBlanc FBlank J EBlusk SBocharnikov VBoelhauve J ABoente Garcia OBoettcher TBohare ABoldyrev ABolognani CBolzonella RBonacci R BBondar NBordelius ABorgato FBorghi SBorsato MBorsuk J TBottalico EBouchiba S ABovill MBowcock T J VBoyer ABozzi CBrandenburg J DBrea Rodriguez ABreer NBrodzicka JBrown JBrundu DBuchanan EBurgos Marcos MBurr CButi CButter J SBuytaert JByczynski WCadeddu SCai HCai YCaillet ACalabrese RCalefice LCalvi MCalvo Gomez MCamargo Magalhaes PCambon Bouzas J ICampana PCampos A CCampoverde Quezada A FCapelli SCaporale MCapriotti LCaravaca-Mora RCarbone ACarcedo Salgado LCardinale RCardini ACarniti PCarus LCasais Vidal ACaspary RCasse GCattaneo MCavallero GCavallini VCelani SCelestino ICesare SChadwick A JChahrour IChang HCharles MCharpentier PhChatzianagnostou ECheaib RChefdeville MChen CChen JChen SChen ZChen Hu ACherif MChernov AChernyshenko SChiotopoulos XChobanova VChrzaszcz MChubykin AChulikov VCiambrone PCid Vidal XCiezarek GCifra PClarke P E LClemencic MCliff H VClosier JCocha Toapaxi CCoco VCogan JCogneras ECojocariu LCollaviti SCollins PColombo TColonna MComerma-Montells ACongedo LConnaughton JContu ACooke NCordova GCoronel CCorredoira ICorreia ACorti GCottee Meldrum JCouturier BCraik D CCruz Torres MCubero Campos MCurras Rivera ECurrie RDa Silva C LDadabaev SDai XDall'Occo EDalseno JD'Ambrosio CDaniel JDarze GDavidson ADavies J EDe Aguiar Francisco ODe Angelis CDe Benedetti Fde Boer JDe Bruyn KDe Capua SDe Cian MDe Freitas Carneiro Da Graca UDe Lucia EDe Miranda J MDe Paula LDe Serio MDe Simone PDe Vellis Fde Vries J ADebernardis FDecamp DDekkers SDel Buono LDelaney BDeng JDenysenko VDeschamps ODettori FDey BDi Nezza PDiachkov IDidenko SDing SDing YDittmann LDobishuk VDocheva A DDoheny ADong CDordei FDos Reis A 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RLiu DLiu F LLiu GLiu KLiu SLiu WLiu YLiu YLiu Y LLoachamin Ordonez GLobo ILobo Salvia ALoi ALong TLopes F C LLopes J HLopez Huertas ALopez Iribarnegaray CLópez Soliño SLu QLucarelli CLucchesi DLucio Martinez MLuo YLupato ALuppi ELynch KLyu X-RMa G MMa HMaccolini SMachefert FMaciuc FMack BMackay IMackey L MMadhan Mohan L RMadurai M JMagdalinski DMaisuzenko DMalczewski J JMalde SMalentacca LMalinin AMaltsev TManca GMancinelli GMancuso CManera Escalero RManganella F MManuzzi DMarangotto DMarchand J FMarchevski RMarconi UMariani EMariani SMarin Benito CMarks JMarshall A MMartel LMartelli GMartellotti GMartinazzoli LMartinelli MMartinez Gomez DMartinez Santos DMartinez Vidal FMartorell I Granollers AMassafferri AMatev RMathad AMatiunin VMatteuzzi CMattioli K RMauri AMaurice EMauricio JMayencourt PMazorra de Cos JMazurek MMazzanti Tarancon DMcCann MMcHugh N TMcNab AMcNulty RMeadows BMelnychuk DMendoza Granada DMenendez Valdes Perez PMeng F MMerk MMerli AMeyer Garcia LMiao DMiao HMikhasenko 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HWang JWang JWang JWang JWang MWang N WWang RWang XWang XWang X WWang YWang YWang Y HWang ZWang ZWard J AWaterlaat MWatson N KWebsdale DWei YWeida ZWendel JWesthenry B D CWhite CWhitehead MWhiter EWiederhold A RWiedner DWiegertjes M AWild CWilkinson GWilkinson M KWilliams MWilliams M JWilliams M R JWilliams RWilliams SWilliams ZWilson F FWinn MWislicki WWitek MWitola LWolf TWood EWormser GWotton S AWu HWu JWu XWu YWu ZWyllie KXian SXiang ZXie YXing T XXu AXu LXu MXu ZXu ZXu ZYadav SYang KYang XYang YYang YYang ZYeung HYin HYin XYu C YYu JYuan XYuan YZamora Saa J AZavertyaev MZdybal MZenesini FZeng CZeng MZhang CZhang DZhang JZhang LZhang RZhang SZhang S LZhang YZhang Y ZZhang ZZhao YZhelezov AZheng S ZZheng X ZZheng YZhou TZhou XZhovkovska VZhu L ZZhu XZhu XZhu YZhukov VZhuo JZuliani DZunica G