AREG ELISA kit
- Known as:
- AREG Enzyme-linked immunosorbent assay test reagent
- Catalog number:
- DL-AREG-Ra
- Product Quantity:
- 96T
- Category:
- Elisa Kits
- Supplier:
- WDSTD
- Gene target:
- AREG ELISA kit
Related genes to: AREG ELISA kit
- Gene:
- AREG NIH gene
- Name:
- amphiregulin
- Previous symbol:
- SDGF, AREGB
- Synonyms:
- -
- Chromosome:
- 4q13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1989-05-19
- Date modifiied:
- 2015-08-24
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- The decay B^{±}→K_{S}^{0}π^{±}, with a CP asymmetry expected to be close to zero in the standard model, is theoretically clean and sensitive to potential new physics. An analysis of the decays B^{±}→K_{S}^{0}π^{±} and B^{±}→K_{S}^{0}K^{±} is performed using proton-proton collision data collected by the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 5.4 fb^{-1}. The CP asymmetries are determined to be A^{CP}(B^{±}→K_{S}^{0}π^{±})=-0.028±0.009±0.009 and A^{CP}(B^{±}→K_{S}^{0}K^{±})=0.118±0.062±0.031, and the branching fraction ratio is measured to be B(B^{±}→K_{S}^{0}K^{±})/B(B^{±}→K_{S}^{0}π^{±})=0.055±0.004±0.002, where the first uncertainties are statistical and the second are systematic. These results are the most precise measurements of these quantities to date. A search for the rare decay B_{c}^{±}→K_{S}^{0}K^{±} is also performed. No significant signal is observed, and the upper limit on the product of the branching fraction ratio B(B_{c}^{±}→K_{S}^{0}K^{±})/B(B^{±}→K_{S}^{0}π^{±}) and the fragmentation-fraction ratio f_{c}/f_{u} is set to be 0.015 (0.016) at the 90% (95%) confidence level. - Source: PubMed
Aaij RAbdelmotteleb A S WAbellan Beteta CAbudinén FAckernley TAdefisoye A AAdeva BAdinolfi MAdlarson PAgapopoulou CAidala C AAjaltouni ZAkar SAkiba KAkthar MAlbicocco PAlbrecht JAleksiejunas RAlessio FAlvarez Cartelle PAmalric RAmato SAmey J LAmhis YAn LAnderlini LAndersson MAndreola PAndreotti MAndres Estrada SAnelli AAo DArata CArchilli FAreg ZArgenton MArguedas Cuendis SArnone LArtamonov AArtuso MAslanides EAtaíde Da Silva RAtzeni MAudurier BAuthier J ABacher DBachiller Perea IBachmann SBachmayer MBack J JBaladron Rodriguez PBalagura VBalboni ABaldini WBaldwin ZBalzani LBao HBaptista de Souza Leite JBarbero Pretel CBarbetti MBarbosa I RBarlow R JBarnyakov MBarsuk SBarter WBartz JBashir SBatsukh BBattista P BBay ABeck ABecker MBedeschi FBediaga I BBehling N ABelin SBellavista ABelous KBelov IBelyaev IBenane GBencivenni GBen-Haim EBerezhnoy ABernet RBernet Andres SBertolin ABetti FBex JBezshyyko OBhattacharya SBieker M SBiesuz N VBiolchini ABirch MBishop F C RBitadze ABizzeti ABlake TBlanc FBlank J EBlusk SBocharnikov VBoelhauve J ABoente Garcia OBoettcher TBohare ABoldyrev ABolognani CBolzonella RBonacci R BBondar NBordelius ABorgato FBorghi SBorsato MBorsuk J TBottalico EBouchiba S ABovill MBowcock T J VBoyer ABozzi CBrandenburg J DBrea Rodriguez ABreer NBrodzicka JBrown JBrundu DBuchanan EBurgos Marcos MBurke A TBurr CButi CButter J SBuytaert JByczynski WCadeddu SCai HCai YCaillet ACalabrese RCalderon Ramirez SCalefice LCalvi MCalvo Gomez MCamargo Magalhaes PCambon Bouzas J ICampana PCampoverde Quezada A FCapelli SCaporale MCapriotti LCaravaca-Mora RCarbone ACarcedo Salgado LCardinale RCardini ACarniti PCarus LCasais Vidal ACaspary RCasse GCattaneo MCavallero GCavallini VCelani SCelestino ICesare SChadwick A JChahrour IChang HCharles MCharpentier PhChatzianagnostou ECheaib RChefdeville MChen CChen JChen SChen ZChen Hu ACherif MChernov AChernyshenko SChiotopoulos XChobanova VChrzaszcz MChubykin AChulikov VCiambrone PCid Vidal XCiezarek GCifra PClarke P E 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CGovorkova EGrabowski J PGranado Cardoso L AGraugés EGraverini EGrazette LGraziani GGrecu A TGrieser N AGrillo LGromov SGu CGuarise MGuerry LGuseinov A-KGushchin EGuz YGys THabermann KHadavizadeh THadjivasiliou CHaefeli GHaen CHaken SHallett GHamilton P MHammerich JHan QHan XHansmann-Menzemer SHao LHarnew NHarris T HHartmann MHashmi SHe JHeatley NHedes AHemmer FHenderson CHenderson RHenderson R D LHennequin A MHennessy KHenry LHerd JHerrero Gascon PHeuel JHeyn AHicheur AHijano Mendizabal GHorswill JHou RHou YHouston D CHowarth NHu WHu XHulsbergen WHunter R JHushchyn MHutchcroft DIdzik MIlin DIlten PIniukhin AIohner AIshteev AIvshin KJage HJaimes Elles S JJakobsen SJakoubek TJans EJashal B KJawahery AJayaweera CJevtic VJia ZJiang EJiang XJiang YJiang Y JJimenez Moya EJindal NJohn MJohn Rubesh Rajan AJohnson DJones C RJoshi SJost BJuan Castella JJurik NJuszczak IKalecinska KKaminaris DKandybei SKane MKang YKar CKaracson MKauniskangas AKautz J WKazanecki M KKeizer FKenzie MKetel TKhanji 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Martinez MLuo YLupato ALuppi ELynch KLyu X-RMa G MMa HMaccolini SMachefert FMaciuc FMack BMackay IMackey L MMadhan Mohan L RMadurai M JMagdalinski DMaisuzenko DMalczewski J JMalde SMalentacca LMalinin AMaltsev TManca GMancinelli GMancuso CManera Escalero RManganella F MManuzzi DMarangotto DMarchand J FMarchevski RMarconi UMariani EMariani SMarin Benito CMarks JMarshall A MMartel LMartelli GMartellotti GMartinazzoli LMartinelli MMartinez Gomez DMartinez Santos DMartinez Vidal FMartorell I Granollers AMassafferri AMatev RMathad AMatiunin VMatteuzzi CMattioli K RMauri AMaurice EMauricio JMayencourt PMazorra de Cos JMazurek MMcCann MMcHugh N TMcNab AMcNulty RMeadows BMelnychuk DMendoza Granada DMenendez Valdes Perez PMeng F MMerk MMerli AMeyer Garcia LMiao DMiao HMikhasenko MMilanes D AMinotti AMinucci EMiralles TMitreska BMitzel D SMocanu RModak AMoeser LMoise R DMolina Cardenas E FMombächer TMonk MMonnard TMonteil SMorcillo Gomez AMorello GMorello M JMorgenthaler M PMoro AMoron JMorren WMorris A BMorris A GMountain RMu Z MMuhammad EMuheim FMulder MMüller KMuñoz-Rojas FMurta RMytrochenko VNaik PNakada TNandakumar RNanut TNapoletano GNasteva INeedham MNekrasova ENeri NNeubert SNeufeld NNeustroev PNicolini JNicotra DNiel E MNikitin NNisi LNiu QNjoki B KNogarolli PNogga PNormand CNovoa Fernandez JNowak GNunez CNur H NOblakowska-Mucha AObraztsov VOeser TOkhotnikov AOkhrimenko OOldeman ROliva FOlivart Pino EOlocco MO'Neil R HOrdonez Soto J SOsthues DOtalora Goicochea J MOwen POyanguren AOzcelik OPaciolla FPadee APadeken K OPagare BPajero TPalano APalini LPalutan MPan CPan XPanebianco SPaniskaki SPanshin GPaolucci LPapanestis APappagallo MPappalardo L LPappenheimer CParkes CParmar DPassaleva GPassaro DPastore APatel MPatoc JPatrignani CPaul APawley C JPellegrino APeng JPeng XPepe Altarelli MPerazzini SPereima DPereira Da Costa HPereira Martinez MPereiro Castro APerez CPerret PPerrevoort APerro APeters M JPetridis KPetrolini APezzulo SPfaller J PPham HPica LPiccini MPiccolo LPietrzyk BPietrzyk GPilato R NPinci DPisani FPizzichemi MPlacinta V MPlo Casasus MPoeschl TPolci FPoli Lener MPoluektov APolukhina NPolyakov IPolycarpo EPonce SPopov DPopp KPoslavskii SPrasanth KProuve CProvenzano DPugatch VPuicercus Gomez APunzi GPybus J RQian Q QQian WQin NQuagliani RRabadan Trejo R IRacz RRademacker J HRama MRamírez García MRamos De Oliveira VRamos Pernas MRangel M SRatnikov FRaven GRebollo De Miguel MRedi FReich JReiss FRen ZResmi P KRibalda Galvez MRibatti RRicart GRiccardi DRicciardi SRichardson KRichardson-Slipper MRiehn FRinnert KRobbe PRobertson GRodrigues ERodriguez Alvarez ARodriguez Fernandez ERodriguez Lopez J ARodriguez Rodriguez ERoensch JRogachev ARogovskiy ARolf D LRoloff PRomanovskiy VRomero Vidal ARomolini GRonchetti FRong TRotondo MRoy S RRudolph M SRuiz Diaz MRuiz Fernandez R ARuiz Vidal JSaavedra-Arias J JSaborido Silva J JSacha Emile R S E RSagidova NSahoo DSahoo NSaitta BSalomoni MSanderswood ISantacesaria RSantamarina Rios CSantimaria MSantoro LSantovetti ESaputi ASaranin DSarnatskiy ASarpis GSarpis MSatriano CSatta ASaur MSavrina DSazak HSborzacchi FScarabotto ASchael SScherl SSchiller MSchindler HSchmelling MSchmidt BSchmidt NSchmitt SSchmitz HSchneider OSchopper ASchulte NSchune M HSchwering GSciascia BSciuccati AScriven GSegal ISellam SSemennikov ASenger TSenghi Soares MSergi ASerra NSestini LSeuthe ASevilla Sanjuan BShang YShangase D MShapkin MSharma R SShchemerov IShchutska LShears TShekhtman LShen ZSheng SShevchenko VShi BShi QShi W SShimizu YShmanin EShorkin RShupperd J DSilva Coutinho RSimi GSimone SSingha MSkidmore NSkwarnicki TSlater M WSmith ESmith MSoares Lavra LSokoloff M DSoler F J PSolomin ASolovev ASolovieva KSommerfeld N SSong RSong YSong YSong Y SSouza De Almeida F LSouza De Paula BSowa K MSpadaro Norella ESpedicato ESpeer J GSpradlin PStagni FStahl MStahl SStanislaus SStefaniak MSteinkamp OStrekalina DSu YSuljik FSun JSun JSun LSundfeld DSutcliffe WSvihra PSvintozelskyi VSwientek KSwystun FSzabelski ASzumlak TTan YTang YTang Y TTat M DTeijeiro Jimenez J ATerentev ATerzuoli FTeubert FThomas EThompson D J DThomson-Strong A RTilquin HTisserand VT'Jampens STobin MTodorov T TTomassetti LTonani GTong XTork TToscano LTou D YTrippl CTuci GTuning NUecker L HUkleja AUnverzagt D JUpadhyay AUrbach BUsachov AUstyuzhanin AUwer UVagnoni VVaitkevicius AValcarce Cadenas VValenti GValls Canudas Nvan Eldik JVan Hecke Hvan Herwijnen EVan Hulse C BVan Laak Rvan Veghel MVasquez GVazquez Gomez RVazquez Regueiro PVázquez Sierra CVecchi SVelilla Serna JVelthuis J JVeltri MVenkateswaran AVerdoglia MVesterinen MVetens WVico Benet DVidrier Villalba PVieites Diaz MVilasis-Cardona XVilella Figueras EVilla AVincent PVivacqua BVolle F CVom Bruch DVoropaev NVos KVrahas CWagner JWalsh JWalton E JWan GWang AWang BWang CWang GWang HWang JWang JWang JWang JWang MWang N WWang RWang XWang XWang X WWang YWang YWang Y HWang ZWang ZWard J AWaterlaat MWatson N KWebsdale DWei YWeida ZWendel JWesthenry B D CWhite CWhitehead MWhiter EWiederhold A RWiedner DWiegertjes M AWild CWilkinson GWilkinson M KWilliams MWilliams M JWilliams M R JWilliams RWilliams SWilliams ZWilson F FWinn MWislicki WWitek MWitola LWolf TWood EWormser GWotton S AWu HWu JWu XWu YWu ZWyllie KXian SXiang ZXie YXing T XXu AXu LXu MXu ZXu ZXu ZYadav SYang KYang XYang YYang YYang ZYeroshenko VYeung HYin HYin XYu C YYu JYuan XYuan YZamora Saa J AZavertyaev MZdybal MZenesini FZeng CZeng MZhang CZhang DZhang JZhang LZhang RZhang SZhang S LZhang YZhang Y ZZhang ZZhao YZhelezov AZheng S ZZheng X ZZheng YZhou TZhou XZhou YZhovkovska VZhu L ZZhu XZhu XZhu YZhukov VZhuo JZuliani DZunica G - Vasculopathy is a core pathological feature of systemic sclerosis (SSc), but its immune regulatory mechanisms remain incompletely understood. In particular, the expression patterns, clinical relevance, and functional roles of CD8CD28 and CD8CD28 angiogenic T cell (Tang) subpopulations in SSc have not been fully defined. This study aimed to systematically investigate the distribution, clinical significance, and molecular characteristics of these Tang subsets in SSc. We identified CD8 Tang subpopulations in the lung tissue of patients with SSc-associated interstitial lung disease (SSc-ILD), with a gradual decrease in CD28-related signals along the inferred differentiation trajectory. In the peripheral blood of patients with SSc, CD8CD28 Tang were increased, whereas CD8CD28 Tang were decreased. These alterations were associated with vascular complications, including ILD, digital ulcers, and advanced microvascular lesions, as well as with disease activity, and may serve as biomarkers of treatment response. Functional experiments showed that CD8CD28 Tang impaired endothelial cell proliferation, migration, tube formation, and survival through a GZMB-dependent mechanism associated with reduced Akt activation, whereas CD8CD28 Tang exerted protective effects through VEGF/AREG-related activation of EGFR/Erk signaling. In summary, our data support an association between CD8CD28/CD8CD28 Tang imbalance and clinical parameters of vasculopathy in SSc, while in vitro findings indicate distinct endothelial-injurious and endothelial-protective functions of these two subsets, suggesting that they may contribute to vascular dysfunction in SSc. - Source: PubMed
Publication date: 2026/05/08
Shen HaomiaoLiu RenliSun HaoyangMiao JinlinZheng Zhaohui - Glioma exhibits significant molecular heterogeneity, necessitating improved understanding of molecular subtypes for personalized treatment strategies. - Source: PubMed
Publication date: 2026/05/08
Wang YuanhanLi LongHu XingHan LonghuZhang YihanZhou ZhisenLiu WeiYang Song - γδ T cells provide mucosal defense against infection while also contributing to tissue repair. However, data regarding the effect of the human lung environment on γδ T cell functionality remains limited. To address whether lung inflammation impacts γδ T cell functionality, we analyzed lung and matched hilar lymph node (LN) tissue from deceased donors and patients with interstitial lung disease (ILD). We performed high-parameter spectral flow cytometry to examine the expression pattern of phenotypic biomarkers and assess ex vivo function. We identified lung-specific enrichment of γδ T cells with an effector memory phenotype relative to matched regional LN. We then used an ex vivo stimulation approach to interrogate the capacity to protect against infection (granzyme B [GzmB], interferon-γ [IFNγ] and tumor necrosis factor [TNFα]) and promote epithelial cell proliferation (amphiregulin [AREG]). We found that γδ T cells in lung and LN from deceased donors had similar functional properties. While γδ T cell populations from ILD lungs largely maintained cytokine production capacity, expression was diminished relative to LN counterparts. Importantly, lung γδ T cells maintained polyfunctional GzmB, IFNγ and TNFα expression across cohorts. Overall, we report human lung γδ T cells are regionally distinct with conserved functionality in a fibrotic environment. - Source: PubMed
Publication date: 2026/04/27
Taber AlexisFrutoso MariePotchen NicoleKoehne Amanda LSchmitz ChelseaMorrell Eric DPrlic MartinWright Shelton W - Cancer-associated fibroblasts (CAFs) within the tumour microenvironment play a pivotal role in colorectal cancer (CRC) progression and therapeutic resistance. Serine/threonine protein kinase 25 (STK25) exerts multiple roles in tumourigenesis; however, its role in mediating tumour-stroma crosstalk remains largely unexplored. - Source: PubMed
Hou YifanChen JiangboHao HaoSong TongkunSong LinXing PuWeng KaiRan YumengYang XinyingQiao XiaowenChen JieYao RuibinYang HongChen LeiDi JiaboXu KaiSu XiangqianJiang Beihai