Reagent Reservoir with caps,60ml
- Known as:
- Reagent Reservoir caps,60ml
- Catalog number:
- 360002
- Product Quantity:
- 5 Qty/Pack
- Category:
- -
- Supplier:
- Nest
- Gene target:
- Reagent Reservoir with caps 60ml
Related genes to: Reagent Reservoir with caps,60ml
- Gene:
- CAPS NIH gene
- Name:
- calcyphosine
- Previous symbol:
- -
- Synonyms:
- CAPS1, MGC126562
- Chromosome:
- 19p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1990-05-31
- Date modifiied:
- 2016-07-18
Related products to: Reagent Reservoir with caps,60ml
Related articles to: Reagent Reservoir with caps,60ml
- We report a simple design strategy to introduce lithium-responsiveness into N-capped peptide low-molecular-weight gelators by incorporating the FFD tripeptide motif (FF extended with Asp). Asp adds an oxygen-rich carboxylate residue that enables cation-mediated assembly. In high pH aqueous solutions, 2NapFFD shows a pronounced cation selectivity. Li generates highly viscous, shear-thinning solutions with birefringent textures, while other Group 1 metals and bulky organic counterions result in low-viscosity and weakly ordered solutions. SAXS and SANS reveal that the addition of Li produces substantially extended micellar structures consistent with long cylindrical assemblies, whereas other monovalent cations lead to the formation of short cylindrical objects. The Li selectivity is intrinsic to the FFD sequence, with other aromatic caps tuning packing and mesoscale order. Finally, dialysis-driven Li exchange induces gelation and enables us to quantify the Li uptake by ICP-OES, illustrating potential for selective lithium capture. - Source: PubMed
Publication date: 2026/04/13
Ghosh DipankarSchweins RalfSmith Andrew JAdams Dave J - Cyclase-associated proteins (CAP1 and CAP2) are conserved actin-regulatory proteins essential for cytoskeletal remodeling and cell motility. Their protein-level expression patterns and clinicopathologic significance in cutaneous melanoma remain poorly defined. CAP1 and CAP2 were evaluated via immunohistochemistry on a tissue microarray of benign nevi and cutaneous melanomas. Cytoplasmic staining in dermal melanocytes was scored (0-3; percentage and intensity). Public transcriptomic data were used to assess tumor stage-correlated mRNA levels. Functional annotation was performed using Search Tool for the Retrieval of Interacting Genes/Protein and Gene Ontology analyses, and survival was analyzed via Kaplan-Meier and Cox regression. CAP1/CAP2 mRNA was upregulated in melanoma versus bulk normal skin, with metastatic tumors exhibiting higher expression than primary tumors. Elevated expression also correlated with advanced tumor stage. CAP1 and CAP2 protein levels were significantly higher in melanomas than in benign nevi (P < 0.0001). In primary melanomas, elevated CAP1 and CAP2 expression scores correlated with adverse pathologic features, including increased Breslow depth, higher mitotic rate, and advanced T stage (P < 0.05). High expression of CAP1 (score = 3) and CAP2 (score ≥ 2) was significantly associated with shorter disease-specific survival (P = 0.0005 and P = 0.0055). While prognostic on univariate analysis, CAPs were not independent predictors in multivariate models. Network enrichment linked CAPs to actin dynamics, cyclic adenosine monophosphate-associated signaling, and cell morphogenesis. CAP1 and CAP2 are overexpressed in cutaneous melanoma and correlate with aggressive pathologic features and shorter survival, suggesting an association between CAP expression and cytoskeletal regulatory programs relevant to melanoma progression. - Source: PubMed
Publication date: 2026/04/21
Ma WeijieWen JiexiLiu Catherine YZaki LorrainePalisoul Scott MJobbagy SomaYan Shaofeng - We demonstrate the modulation of coherent acoustic phonons (CAPs) and their response to high excitation densities in AlGaN/GaN heterostructures under ultrafast near-band gap optical excitation. Displacively excited CAPs induce a strain-modulated piezoelectric field, modulating the transmission of the probe beam through the bulk Franz-Keldysh effect, and manifest as a phase flip when photon energy approaches the intrinsic bandgap. A large initial amplitude of CAP is observed in GaN, followed by a rapid decay arising from screening by the piezoelectric field. In the AlGaN/GaN heterostructure, the top strained layers enhance CAP-piezoelectric coupling. Additionally, the higher thermal conductivity of the top layers and the intrinsic nature of the GaN layer in the heterostructure play a significant role in maintaining phonon coherence due to reduced phonon-phonon scattering and phonon-impurity scattering, respectively. The excited acoustic phonons are long-lived, with high amplitude, exhibiting cosinusoidal displacive behavior that persists due to the interplay between strain waves, piezoelectric field modulation, deformation potential coupling, and thermoelastic expansion. Observed phonon frequencies between 40 and 80 GHz are governed by the acoustic transit time and pump wavelength. We also observe Brillouin frequency components in the range 100-120 GHz, with a significantly long decay time. Furthermore, inhomogeneous plasma distribution modifies the phonon frequency and induces coupled phonon oscillations, which are observed as a beating pattern with frequency content in the sub-THz and THz regimes. These experimental conditions are analogous to high-field transport under electrical injection, where the carrier excitation mechanism differs but the energy release to the phonon subsystem resembles that under optical excitation. This work presents a pathway for the development of on-demand coherent phonon sources without a superlattice structure, thereby opening up the possibility of understanding plasmon-phonon interactions in AlGaN/GaN heterostructures for solid-state applications. - Source: PubMed
Publication date: 2026/04/21
Bhat Shazan AhmadGanguly SwaroopSaha Dipankar - DNA methylation is a key regulator of tissue-specific gene expression, cell differentiation, and development. In mammals, DNA methylation predominantly occurs as 5-methylcytosine (5mC) at CpG dinucleotides. DNA methylation is a dynamic and reversible process. Increasing evidence indicates that 5-hydroxymethylcytosine (5hmC), an oxidation product of 5mC, plays important roles in chromatin organization and gene regulation. Aberrant 5hmC levels have been associated with various neurological disorders and cancer types. Despite its biological relevance, accurate quantification of 5hmC at single-CpG resolution remains challenging due to its low abundance and methodological limitations of existing detection approaches. - Source: PubMed
Publication date: 2026/04/20
Pühringer KatharinaCzarda PhilippIluca SebastianFehringer BennoSherovski PeceOhindovschi AngelicaHainfellner AndreasReissig LukasWeninger Wolfgang JCichna-Markl Margit - - Source: PubMed
Publication date: 2026/04/21