SW40_41 Tubes with short caps
- Known as:
- SW40_41 Tubes short caps
- Catalog number:
- 1054146
- Product Quantity:
- 1 pack
- Category:
- -
- Supplier:
- Accu
- Gene target:
- SW40_41 Tubes with short caps
Related genes to: SW40_41 Tubes with short caps
- Gene:
- CAPS NIH gene
- Name:
- calcyphosine
- Previous symbol:
- -
- Synonyms:
- CAPS1, MGC126562
- Chromosome:
- 19p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1990-05-31
- Date modifiied:
- 2016-07-18
Related products to: SW40_41 Tubes with short caps
Related articles to: SW40_41 Tubes with short caps
- Alcohol use disorder (AUD) and post-traumatic stress disorder (PTSD) are thought to be significant global contributors to the burden of mental illness. According to recent WHO epidemiological estimates, 3.9% of people worldwide have experienced PTSD at some point in their lives; this number rises to roughly 5.6% among those who have experienced trauma. NAC has shown promise in reducing PTSD symptoms and cravings in veterans, according to recent trials. Our analysis aims to resolve the conflict between results and determine whether NAC is an effective add-on therapy for PTSD, AUD, and co-occurring PTSD/AUD. - Source: PubMed
Publication date: 2026/05/11
Ahmed Mohamed Awad EAmin MufrehAbdalla Yomna EmadAbdelghani AmrEid NourhanSamy AyaKassar OmarAlsaadany Khalid RadwanMansour Mohamed Ezzat M - Psychiatric treatment research has too frequently neglected anger. "Anger management" is widely used to tamp anger down. Yet understanding and expressing anger often have clinical and interpersonal value. Few data address anger in the context of treating patients with posttraumatic stress disorder (PTSD). The authors hypothesized the clinical utility of anger expression rather than suppression, particularly using interpersonal psychotherapy (IPT), which focuses on interpersonal handling of emotions. IPT effects on anger have barely been researched. - Source: PubMed
Publication date: 2026/05/12
Markowitz John CTao BradleyLu JieZhu Xi - - Source: PubMed
Publication date: 2026/05/11
Chen JingyouLuo FangluHe HuicunGalien LaurenOliveira Bre H - Biological information can be encoded in signaling dynamics, which have been implicated in many physiological processes; yet the diversity of dynamic expression profiles driven by a single gene remains unclear. To explore this, we screen 80 chromatin-associated proteins (CAPs) for their potential to drive diverse dynamic gene expression profiles from the same genome-integrated reporter in yeast. Using locus-specific optogenetic recruitment and live-cell microscopy, we measure dynamic expression profiles within single cells. CAP recruitment elicits a range of responses varying in activation delay, strength, production rate, and noise. We find that promoter activity is characterized by graded, rather than switch-like, transitions. A kinetic model with three promoter states and a positive feedback loop successfully captures the key features of expression driven by each CAP. These results reveal the rich dynamic landscape possible from a single gene, offering insights into native cellular processes and enhancing gene expression control in synthetic biology. - Source: PubMed
Publication date: 2026/04/16
Lee Jessica BCaywood Leandra MBasinger RileyAbbott LucasLevering NicholasKeung Albert J - Rhinoviruses (RV) comprise three species, RV-A, RV-B, and RV-C, with approximately 170 types. RV-C is associated with severe respiratory illness, particularly in children and individuals with asthma or chronic obstructive pulmonary disease, underscoring the need for effective antiviral strategies. Progress in RV-C research and drug discovery has been limited by the lack of robust, scalable cell-based infection models that recapitulate the complete RV-C replication cycle. Here, we describe a high-content imaging (HCI)-based high-throughput infection system for RV-C. Rather than relying solely on receptor overexpression, we used a genetically stable fluorescent reporter virus (RV-C15a-mGL) to screen ~300 monoclonal cell lines expressing the RV-C receptor variant CDHR3-Tyr529. This approach identified a clone that efficiently supports RV-C replication and revealed that productive infection depends on determinants beyond receptor abundance alone. Using this clone, we established and validated a robust, scalable screening platform with Z' > 0.75 in both 96- and 384-well formats. The system was readily adapted to additional RV-C types (C11 and C41), as well as RV-A and RV-B. A pilot screen of approximately 10,000 small molecules identified both known and novel RV-C inhibitors, supporting the utility of this platform for antiviral discovery and for advancing the study of RV-C biology. - Source: PubMed
Publication date: 2026/05/11
Lyoo HeyrhyoungAlpizar Yeranddy ASablon CélineRöpke ToonPaulissen JasmineRasulova MadinaThys NathalieYun Chang-SooCho Nam-ChulDallmeier KaiLeyssen PieterHan Soo-BongNeyts JohanThibaut Hendrik Jan