Rat Anti-Mouse IL-12 Antibodies
- Known as:
- Rat Antibody toMouse Interleukin-12 Antibodies
- Catalog number:
- RB-IP-01-114-500
- Product Quantity:
- 500
- Category:
- -
- Supplier:
- Ray Biotech
- Gene target:
- Rat Anti-Mouse IL-12 Antibodies
Related genes to: Rat Anti-Mouse IL-12 Antibodies
- Gene:
- IL12RB1 NIH gene
- Name:
- interleukin 12 receptor subunit beta 1
- Previous symbol:
- IL12RB
- Synonyms:
- CD212
- Chromosome:
- 19p13.11
- Locus Type:
- gene with protein product
- Date approved:
- 1995-09-14
- Date modifiied:
- 2019-04-23
Related products to: Rat Anti-Mouse IL-12 Antibodies
Related articles to: Rat Anti-Mouse IL-12 Antibodies
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Canabrava Paola Borges EcksteinBeauge Roll StanleyAzouz Samir de FigueiredoTimbó Renata VelozoMartins Luciana Pereira FreireRodrigues Bruna CôrtesSantos Naiara Daris DosMedeiros Marcella Palhanode Araújo Andréa MonteiroSantos Agenor de Castro Moreira DosAraújo Carla Nunes deNóbrega Otávio de ToledoKurizky Patrícia ShuMota Licia Maria Henrique daGomes Ciro Martins - Dysbiosis of gut microbiota is well established in coronavirus disease 2019 (COVID-19). While studies have attempted to establish a link between the gut commensal () and COVID-19, the findings have been inconsistent and sometimes controversial. The intestinal microbial abundance information of COVID-19 patients was acquired and analysed from GMrepo database. Subsequently, metabolites, target-genes, and metabolite-target relationships was extracted from GutMGene database. Lastly, coronascape module in Metascape database is used for gene annotation and enrichment analysis in various host cells and tissues after SARS-CoV-2 infection. The results indicated that, in comparison to healthy people, was significantly elevated in COVID-19 patients. This bacterium was found to be associated with heightened expression of IL-10, TLR2, TLR4, CLGN, CLDN4, TJP2, and TJP3, while concurrently experiencing a reduction in the expression of IL-12A and IL-12B in humans. The regulatory genes of primarily enhance responses to viruses and cytokines, positively regulate cell migration, and control epithelial cell proliferation. Our study revealed a significant increase in the gut commensal in COVID-19 patients. This bacterium can modulate host immune responses and may also serve as a probiotic with antiviral properties. - Source: PubMed
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