Sheep Steroidogenic acute regulatory protein ELISA, StAR
- Known as:
- Sheep Steroidogenic acute regulatory protein Enzyme-linked immunosorbent assay test, StAR
- Catalog number:
- E14S0208
- Product Quantity:
- 96 Tests/kit
- Category:
- -
- Supplier:
- BGene
- Gene target:
- Sheep Steroidogenic acute regulatory protein ELISA StAR
Related genes to: Sheep Steroidogenic acute regulatory protein ELISA, StAR
- Gene:
- STAR NIH gene
- Name:
- steroidogenic acute regulatory protein
- Previous symbol:
- -
- Synonyms:
- StAR, STARD1
- Chromosome:
- 8p11.23
- Locus Type:
- gene with protein product
- Date approved:
- 1996-04-24
- Date modifiied:
- 2016-10-05
Related products to: Sheep Steroidogenic acute regulatory protein ELISA, StAR
Related articles to: Sheep Steroidogenic acute regulatory protein ELISA, StAR
- Pain affects more than 1.5 billion people worldwide and remains a leading cause of disability, but currently available analgesics often have limited efficacy and significant adverse effects. In this context, bioactive molecules derived from animal venoms and secretions have emerged as promising novel therapeutic agents. Here, we investigated the antinociceptive and anti-inflammatory properties of cAmbly, a cell-penetrating peptide derived from the C-terminal region of Amblyomin-X, a protein from the salivary gland transcriptome of the Amblyomma sculptum tick. In cultured human sensory-like neurons exposed to an advanced glycation end products (AGEs)-induced pro-nociceptive environment, cAmbly reduced substance P release, increased β-endorphin levels, and restored neurite outgrowth. Proteomic analysis further indicated that these effects mediated by MAPK-related signaling pathways are involved in neuronal sensitization and inflammatory responses. Consistent with these findings, cAmbly reduced capsaicin-induced calcium flux in cultured rat dorsal root ganglion (DRG) neurons, an effect reversed by the opioid antagonist naloxone. Importantly, in in vivo assays, cAmbly reduced pain-like behavior in models of formalin-induced acute nociception and CFA-induced persistent inflammatory pain, and the systemic treatment decreased TNF-α, IL-6, CXCL1, and CCL2 levels in inflamed paw tissues. The antinociceptive effects were reversed by naloxone, confirming the involvement of endogenous opioid pathways. Together, these findings demonstrate that cAmbly attenuates nociceptive signaling in sensory neurons and inflammatory responses through an endogenous opioid-dependent mechanism, highlighting its potential as a novel therapeutic candidate for pain management. - Source: PubMed
Publication date: 2026/08/15
Búfalo Michelle CristianeDallazen Jorge LuizMartins Barbara Behrde Assis Silva Gessica SabrinaHosch Natalia GabrieleAlcantara Queren ApuqueBuri Marcus ViniciusPereira Carlos DeOcesanoOliveira Douglas Souzade Barros Hugo Vigerellide Souza Marcelo MedinaAlvarez-Flores Miryam PaolaTroitiño Vitória Carvalhode Fátima Correia Batista IsabelPicolo GiseleTeixeira CatarinaIbañez Olga Célia MartinezChudzinski-Tavassi Ana MarisaZambelli Vanessa Olzon - While structural covariance analysis is adept at assessing morphometric correlations among broadly distributed brain regions, limited research has focused on alterations in structural covariance networks post-stroke. This study aims to identify significant brain gray matter changes and distinct structural covariance patterns in stroke patients. - Source: PubMed
Lu Juan-JuanXing Xiang-XinQu JiaoWu Jia-JiaMa JieZheng Mou-XiongHua Xu-YunXu Jian-Guang - Respectful maternity care is essential for quality maternal and newborn health services. Interventions to promote respectful care often focus on training, overlooking organisational culture underpinning disrespectful behaviour. This study aimed to evaluate the implementation and effects of the Strengthening Teamwork and Respect (STAR) intervention on organisational learning culture and person-centred maternity care (PCMC). - Source: PubMed
Doherty TanyaFilippi VeroniqueJohn VaughnHaskins LynLand SandraPhewa CleoMapumulo SphindileLuthuli SilondilePenn-Kekana LovedayManda SamuelMoran NeilSibiya RoseMyeza HlengiweHorwood Christiane - Viral myocarditis (VM) affects over 1 million people yearly worldwide and may trigger arrhythmia, heart failure, or sudden death, bringing heavy clinical and economic burdens. TikTok and Bilibili are vital health information hubs, yet unregulated VM video content lacks quality evaluation on Chinese platforms. This cross-sectional study assessed VM video reliability and completeness on both platforms to support evidence-based health guidance. Data collection finished on February 15, 2026. We collected the top 100 default-ranked videos per platform via incognito new accounts searching "viral myocarditis." After screening out ads, irrelevant, recent and duplicate videos, 180 clips (TikTok = 91, Bilibili = 89) were analyzed. Two trained cardiologists scored videos with the 0 to 5 modified DISCERN (instrument for evaluating health information quality) scale and 1 to 5 Global Quality Score and graded 6 disease domains' completeness using a 3-point scale. Nonparametric tests and Spearman correlation were adopted, with P < .05 as the statistical significance threshold. TikTok videos had significantly higher median likes, comments, saves, and shares (all P < .001), while Bilibili videos were longer (139 vs 95 seconds, P = .002). Professional creators accounted for 71.43% of TikTok uploads versus 44.94% on Bilibili, which hosted more nonprofessional contributors. TikTok fully covered symptoms best (40.66%) but ignored epidemiology (83.52% uncovered); Bilibili offered more complete etiology, prevention, and symptom explanations yet lacked epidemiological content. Bilibili contained far more high-rating DISCERN (4-5) and 5-star Global Quality Score videos and no 1-point low-quality clips, unlike TikTok. Engagement metrics were strongly positively correlated on both platforms; video duration weakly negatively correlated with interaction on TikTok but moderately positively correlated on Bilibili. Inter-rater reliability was excellent (r = 0.81-0.96). Bilibili's VM videos outperform TikTok in information completeness and overall quality. TikTok's higher traffic often favors low-quality content, and preventive knowledge coverage is insufficient on both platforms. Such gaps arise from distinct user groups, content formats, and algorithms. Optimized algorithms, medical creator certification, and differentiated science communication can standardize VM online education and help patients access reliable disease management knowledge. - Source: PubMed
Zhu ZipengSu Xuexu - Atomically thin semiconductor junctions offer a platform for probing optoelectronic processes beyond the continuum limit, where reduced screening and strong exciton binding make local fields especially important for charge separation. Yet it remains unclear how individual dopants contribute to the photovoltaic response when the junction thickness becomes comparable with the atomic length scales and smaller than conventional depletion or diffusion lengths. Here we demonstrate this concept by probing the microscopic photoresponse of a van der Waals semiconductor homobilayer containing ionizing acceptors. Using photoconductive atomic force microscopy on vanadium-doped WSe (V:WSe) bilayers, we directly visualize nanometre-scale photocurrent hotspots centred on single dopants, which have opposite current polarities for dopants in the top and bottom layers. Vertical WSe/V:WSe homobilayer devices show that the macroscopic photocurrent scales linearly with dopant concentration and exhibits a compensation voltage that is independent of illumination power and dopant density, in contrast to bulk homojunction devices. Photocurrent spectroscopy and quasi-classical modelling indicate that charged dopants locally convert tightly bound intralayer excitons into charge-separated interlayer states, thereby enabling efficient exciton dissociation within a region of about 1 nm. These results establish dopant-defined point-like junctions as the elementary photovoltaic units in atomically thin homobilayers. - Source: PubMed
Publication date: 2026/08/14
Vu Nam Thanh TrungChen MingjunHo Yi WeiWu QingyunWong Cheng QuanChen YuanBudniak Adam KLoh LeyiVerzhbitskiy IvanWatanabe KenjiTaniguchi TakashiBosman MichelAng Lay KeeTrushin MaximEda Goki