Rat Adiponectin Receptor 1 ELISA , ADIPOR1
- Known as:
- Rat Adiponectin Receptor 1 Enzyme-linked immunosorbent assay test , ADIPOR1
- Catalog number:
- E02A0524
- Product Quantity:
- 96 Tests/kit
- Category:
- -
- Supplier:
- BGene
- Gene target:
- Rat Adiponectin Receptor 1 ELISA ADIPOR1
Related genes to: Rat Adiponectin Receptor 1 ELISA , ADIPOR1
- Gene:
- ADIPOR1 NIH gene
- Name:
- adiponectin receptor 1
- Previous symbol:
- -
- Synonyms:
- PAQR1, ACDCR1
- Chromosome:
- 1q32.1
- Locus Type:
- gene with protein product
- Date approved:
- 2004-06-23
- Date modifiied:
- 2018-05-03
Related products to: Rat Adiponectin Receptor 1 ELISA , ADIPOR1
Related articles to: Rat Adiponectin Receptor 1 ELISA , ADIPOR1
- Obesity is a multifactorial metabolic disorder characterized by excessive adipose accumulation and dysregulated lipid and glucose homeostasis. Marine brown algae contain diverse bioactive compounds with potential metabolic benefits; however, the in vivo anti-obesity effects of remain insufficiently characterized. - Source: PubMed
Publication date: 2026/05/15
Bahtiar AntonWahyudi Dinda Puspita DewiWidiarti RianiSiriamornpun Sirithon - Periodontitis is a chronic inflammatory disease which is initiated by dysbiotic biofilms and maintained by a host who is permissive to inflammation resulting in continuous destruction of periodontal supporting structures. Periodontitis occurs frequently with obesity and type 2 diabetes mellitus and the broader cardiometabolic risk state leading to investigations into the common immunometabolic pathways that link these conditions. Adiponectin, an insulin sensitizing and anti-inflammatory adipokine which can also act as a vasculoprotective and bone-related factor, has been studied as a potential modulator of the relation between periodontal inflammation and systemic metabolic disturbance. This narrative review summarizes the biology of adiponectin and its receptors, human findings relating to both the local and circulating forms of adiponectin in periodontal health and disease, the mechanism in cell and animal models and translational implications and limitations. The literature was reviewed in a narrative manner with particular attention to study quality, compartment-specific biology and any conflicts in evidence and the difference between biological plausibility and clinical relevance. A tendency for a reduction in the circulating, saliva and gingival crevicular fluid levels of adiponectin in periodontitis in human studies, particularly those with co-existing obesity and type 2 diabetes mellitus, can be demonstrated but these finding are often disparate due to variable methods in case definitions, assay techniques, metabolic background of subjects and other confounders. Experimental findings may establish biological plausibility by linking adiponectin signalling with the mechanisms which affect inflammatory responses, endothelial function and matrix homeostasis, osteoclastogenesis and subsequent alveolar bone loss, although adiponectin signalling appears context-specific in its actions and this does not confirm clinical relevance. Evidence suggests adiponectin is a biologically significant, but context-dependent factor within the immunometabolic network which connects periodontal disease with the systemic condition, rather than a sole marker or clinically recognized target for therapeutic intervention. - Source: PubMed
Publication date: 2026/05/08
Mochol MartynaDura WłodzimierzLodigkeit MaikeAndrzejewski PiotrLipski MariuszMazurek-Mochol Małgorzata - Microbiota-derived metabolites are increasingly recognized as modulators of systemic immunity and cancer biology. This study investigates how a structurally distinct lipid from Akkermansia muciniphila influences immune transcriptional programs and their connection to breast cancer (BRCA)-associated pathways. - Source: PubMed
Chaudhary UmaA S AryaA Mythili - Adiponectin (APN) is a multifunctional adipokine secreted by adipose tissue that has recently been recognized for its important neuroprotective effects in central nervous system (CNS) disorders. However, effective targeted interventions and the precise molecular mechanisms of APN and its receptors remain incompletely understood. Activation of cerebral APN receptor 1 (AdipoR1) through APN supplementation, APN receptor agonists, or exercise interventions can exert beneficial effects in CNS disorders. These effects are mediated through signaling pathways such as AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor-alpha (PPARα), leading to enhanced insulin sensitivity, promotion of autophagic clearance of toxic substances, attenuation of neuroinflammation, reduction of oxidative stress and neuronal apoptosis, and improvement of mitochondrial function. This review summarizes the mechanistic associations between APN and various CNS disorders and analyzes the specific intervention strategies, mechanisms, and therapeutic potential of different APN isoforms, APN receptor agonists, and exercise targeting APN receptors. It provides a theoretical basis for exploring effective therapeutic strategies for CNS disorders. In addition, based on the theoretical rationale that both exercise and APN receptor agonists can independently activate the AdipoR1 signaling pathway, future studies may further explore the synergistic effects and potential value of their combined application, thereby providing new research perspectives for promoting brain health. - Source: PubMed
Publication date: 2026/05/21
Li MingmingWu MinGao HaoyangXue XiangliXiao WeihuaZhu Lin - Sleep deprivation is a common phenomenon in modern society and has received widespread attention. However, data about its impact on immune system functions remains scant. - Source: PubMed
Publication date: 2026/05/07
Li XiangWang XiaoyanWang XiaodiBing Dan