DLL1 Antibody (monoclonal) (M01)
- Known as:
- DLL1 Antibody (mab) (M01)
- Catalog number:
- AT1772a
- Category:
- -
- Supplier:
- Abgen
- Gene target:
- DLL1 Antibody (monoclonal) (M01)
Related genes to: DLL1 Antibody (monoclonal) (M01)
- Gene:
- DLL1 NIH gene
- Name:
- delta like canonical Notch ligand 1
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 6q27
- Locus Type:
- gene with protein product
- Date approved:
- 2000-02-11
- Date modifiied:
- 2019-01-03
- Gene:
- GTF2H2B NIH gene
- Name:
- general transcription factor IIH subunit 2B (pseudogene)
- Previous symbol:
- -
- Synonyms:
- DKFZP686M0199
- Chromosome:
- 5q13.2
- Locus Type:
- pseudogene
- Date approved:
- 2008-07-04
- Date modifiied:
- 2015-11-09
- Gene:
- POLR1A NIH gene
- Name:
- RNA polymerase I subunit A
- Previous symbol:
- -
- Synonyms:
- DKFZP586M0122, FLJ21915, RPO1-4, RPA1
- Chromosome:
- 2p11.2
- Locus Type:
- gene with protein product
- Date approved:
- 2003-04-01
- Date modifiied:
- 2017-06-28
- Gene:
- TDRP NIH gene
- Name:
- testis development related protein
- Previous symbol:
- C8orf42
- Synonyms:
- INM01, TDRP1, TDRP2
- Chromosome:
- 8p23.3
- Locus Type:
- gene with protein product
- Date approved:
- 2005-07-28
- Date modifiied:
- 2015-08-26
Related products to: DLL1 Antibody (monoclonal) (M01)
Related articles to: DLL1 Antibody (monoclonal) (M01)
- CD8 (cluster of differentiation 8) T cells contribute to atherosclerosis, but how they affect VSMCs (vascular smooth muscle cells) is unclear. The protective role of CD8 regulatory T cells (Tregs) and in vivo induction strategies also remain undefined. - Source: PubMed
Publication date: 2026/09/09
Gao WentaoHou YangfengLiu JiaxingHo Cheng KiuCheng Alfred Sze-LokWaldmann HermanZhou BinLau James Y WLui Kathy O - The Notch signalling pathway regulates cell fate, proliferation, and differentiation and consists of receptors (Notch1-4), ligands (JAG1-2, DLL1, DLL3-4), and downstream targets. Altered expression of Notch pathway-linked genes has been reported in multiple cancers, although their associations with survival may vary according to tumour type. Their relationship with biological sex and radiotherapy (RT) has been less extensively explored. - Source: PubMed
Publication date: 2026/08/15
O'Hea HelenBourbonne VMarignol Laure - Understanding the regulation of hematopoietic stem and progenitor cell (HSPC) fate and translating it into effective culture strategies remains a significant challenge. Asymmetric lysosomal inheritance during HSPC division has been shown to predict variations in daughter cell activity and fate, yet the underlying regulators remain unclear. Through cell-cell communication analysis of bone marrow single-cell sequencing data, we identified the Notch ligand Delta-like protein 1 (DLL1) as a potential regulator in HSPC asymmetric division (ACD). Interactions between DLL1-presenting microparticles (MP-Ds) and HSPCs were observed in addressable microwell arrays, simulating cellular responses to localized niche signals. Long-term single-cell tracking revealed that MP-D interactions polarized HSPC lysosomes toward the contact site, directing division orientation and consequent asymmetric lysosomal inheritance in paired daughter cells. Furthermore, this co-culture system enhanced long-term hematopoietic reconstitution capacity of HSPCs in serial transplantations. Our findings support an association between HSPC ACD and the presentation mode of DLL1 signals, which enhances the ex vivo maintenance of HSPCs. - Source: PubMed
Publication date: 2026/08/27
Wenjing LiYiting FengDongbo HanYanxiao AoChen Michael WNing LiYuhong JinHaiwei LiangWen LiuXiaoyu ZhuYanan Du - This Mendelian randomization study aimed to systematically investigate the causal associations of 2,821 plasma protein ratios with UC susceptibility and validate potential biomarkers through multi-omics approaches. - Source: PubMed
Publication date: 2026/08/10
Kang KuoWei LinfengLi XuanxuanWang ShalongHuang ChanghaoWu Zhiwei - Osteoporosis (OP) is a common skeletal disease mainly caused by the imbalance between bone formation and bone resorption. Dysfunction and senescence of bone marrow mesenchymal stem cells (BMSCs) are critical pathogenic factors for OP, resulting in impaired osteogenic differentiation, increased adipogenic shift, and enhanced susceptibility to inflammation and oxidative stress. Therefore, the purpose of this review is to systematically synthesize current evidence on how Icariin (ICA)-a major bioactive flavonoid from Epimedium-exhibits therapeutic potential against OP by targeting BMSC senescence and regulating multiple underlying signaling networks. - Source: PubMed
Publication date: 2026/07/28
Wang ChengjieWu ZhenyuXu YaweiLi YuyiMan ZhenweiLiu KangWang JianLin WenlinQie FengqingShi XiaolinYuan Yifeng