GAST Antibody(Ascites)
- Known as:
- GAST Antibody(Ascites)
- Catalog number:
- AM2046a-ev20
- Category:
- -
- Supplier:
- Abgen
- Gene target:
- GAST Antibody(Ascites)
Related genes to: GAST Antibody(Ascites)
- Gene:
- GAST NIH gene
- Name:
- gastrin
- Previous symbol:
- GAS
- Synonyms:
- -
- Chromosome:
- 17q21.2
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-22
- Date modifiied:
- 2015-08-25
Related products to: GAST Antibody(Ascites)
Related articles to: GAST Antibody(Ascites)
- Leaf angle is a key agronomic trait that determines plant architecture and grain yield in rice. Although brassinosteroids (BRs) are known to play a central role in regulating leaf angle, the upstream transcriptional regulatory network remains elusive. Here, we characterized the lla (large leaf angle) mutant which carried a T-DNA insertion in the promoter of OsWRKY11 (a WRKY transcription factor) and exhibits significantly enlarged leaf angles at both seedling and mature stages. We demonstrated that the large leaf angle phenotype of lla was caused by the T-DNA insertion in the promoter of OsWRKY11, leading to its pronounced upregulation. Overexpression of OsWRKY11 recapitulated the lla phenotype, whereas knockdown of OsWRKY11 in the lla background restored leaf angle to wild-type levels, establishing OsWRKY11 as a positive regulator of this trait. Interestingly, the lla mutants are hypersensitive to exogenous BR treatment and accumulate higher levels of the bioactive BR castasterone. Further analyses showed that OsWRKY11 directly binds to W-box elements in the promoter of OsGSR1(a GAST family protein), a known positive regulator of BR biosynthesis, and activates its transcription. Genetic analysis revealed that OsWRKY11 acts upstream of OsGSR1 in the same genetic pathway to regulate leaf angle. Together, our findings uncover an OsWRKY11-OsGSR1 module that fine-tunes leaf angle by modulating BR homeostasis. - Source: PubMed
Publication date: 2026/06/30
Wu LianGao XiuqingWang DekaiSun ShuhuiLi JingCao YuxinChu JinfangLi YuXu RanLi YunhaiLi Na - Equality in marriage is an important element of healthy relationships. Religious marriages differ from those of non-religious or religiously ambiguous individuals. How religious couples experience equality in marriage is an understudied process. A grounded theory design was used to understand how Latter-day Saint couples experience marital power sharing. Thirty-one participants (fifteen opposite sex couples and one wife) participated in 46 interviews where they discussed their marital dynamics, especially surrounding their perceived influence of The Church of Jesus Christ of Latter-day Saints and power sharing. Four interrelated processes surfaced from these interviews: interacting influences (one's family of origin, the Church, and culture), self-in-relationship (including one's self-concept, self-awareness, examination of beliefs, and healing and reconciliation), relational processes (including taking relational responsibility, balancing relational influence, attuning to one's partner, and engaging in emotional exposure), and identity formation ("we" vs. "me"). Implications and applications for clinical practice are discussed. - Source: PubMed
Young BonnieSeedall RyanRobinson DaveGast JulieKline CarolineMason Patrick - Preoperative planning software has gained traction in shoulder arthroplasty, enabling surgeons to better visualize patient's anatomy and optimize implant positioning. Widespread adoption of such tools depends not only on their efficacy but also on surgeon satisfaction and perceived utility in day-to-day practice. However, data on surgeons' satisfaction and perceived utility of such software remain limited. This survey aimed to evaluate surgeons' overall satisfaction, perception and the willingness to recommend the software as a training tool for fellows. - Source: PubMed
Publication date: 2026/06/10
Reynier MaudShank SarahVenegoni MatthewRegling Matthiasde Gast Arthur - Tuberculosis (TB) continues to be a major public health concern. Thus, identifying individuals at risk of progression to active disease is important for community health but remains difficult. To address this issue, we analysed plasma proteomic data from the UK Biobank to investigate host protein signatures associated with TB. The size of the prospective cohort (~ 500,000) combined with deep proteomic analysis (2,920 plasma proteins) allowed us to perform analysis on 42 individuals diagnosed with TB either before or after sampling, alongside matched controls with no history of TB. Using this approach, we identified significantly differentially expressed proteins (e.g. CDCP1, GAST) in individuals affected by TB, suggesting proteomics alternations that precede clinical onset and persist years after diagnosis. Functional annotation of significant proteins indicated involvement of immune and signalling pathways associated with chronic inflammatory responses and host defence mechanisms. These findings help advance the understanding of TB pathology and offer the potential for use of specific plasma proteins in the development of point of care risk assessment and diagnostic tools. - Source: PubMed
Publication date: 2026/06/06
Koziar NataliaWhetton Anthony DGeifman Nophar - Cystic fibrosis (CF) has profoundly changed since the introduction of CF Transmembrane Conductance Regulator modulator therapies (CFTRmt), a class of medications that improve function of the CFTR protein encoded by certain CF-causing gene mutations. Amongst these, the triple combination therapy elexacaftor-tezacaftor-ivacaftor (ETI) has been the most impactful and widely used to date. Given chronic respiratory infection and concomitant inflammation is the leading cause of morbidity and early mortality for the majority in CF, what is not certain are the long-term effects of ETI therapy on the respiratory microbiota and pathogens embedded within. Here, we assessed the effects of ETI CFTRmt over 3 years on the respiratory microbiota, using sputum and cough swab samples, from a multi-centre cohort of 276 adults with CF (awCF) from 6 CF centres in the UK, USA, and Canada, and compared to a non-CF healthy cohort. - Source: PubMed
Publication date: 2026/05/30
Gavillet HelenHatfield Lauren RHardman MichelleMarsh RyanEinarsson Gisli GThornton Christina SParkins Michael DDuckers JamieBomberger Jennifer MHilliam YasminLee Stella ELord Robert WJones AndrewHorsley AlexanderDaniels Thomas W VTeneback Charlotte CRivett Damian Wvan der Gast Christopher