PA_FB_W w_o cap1
- Known as:
- PA_FB_W w_o cap1
- Catalog number:
- 233421
- Product Quantity:
- 1
- Category:
- -
- Supplier:
- Herolab
- Gene target:
- PA_FB_W w_o cap1
Related genes to: PA_FB_W w_o cap1
- Gene:
- CAP1 NIH gene
- Name:
- cyclase associated actin cytoskeleton regulatory protein 1
- Previous symbol:
- -
- Synonyms:
- CAP
- Chromosome:
- 1p34.2
- Locus Type:
- gene with protein product
- Date approved:
- 2003-07-17
- Date modifiied:
- 2017-05-17
Related products to: PA_FB_W w_o cap1
Adenylyl Cyclase Associated Protein 1 (CAP1) Organism: Homo sapiens (Human) Source: Escherichia coliAdenylyl Cyclase Associated Protein 1 (CAP1) Organism: Homo sapiens (Human) Source: Escherichia coliAdenylyl Cyclase Associated Protein 1 (CAP1) Organism: Homo sapiens (Human) Source: Escherichia coliAdenylyl cyclase-associated protein 1,ASP-56 protein,CAP,CAP 1,CAP1,Pig,Sus scrofaAdenylyl cyclase-associated protein 1,Bos taurus,Bovine,CAP 1,CAP1Adenylyl cyclase-associated protein 1,CAP,CAP 1,CAP1,Homo sapiens,HumanAdenylyl cyclase-associated protein 1,Cap,CAP 1,Cap1,Mch1,Rat,Rattus norvegicusAdenylyl cyclase-associated protein 1,Cap,CAP 1,Cap1,Mouse,Mus musculusAnserine Adenylyl Cyclase Associated Protein 1 Elisa Kit (CAP1)Anserine anti - Adenylyl Cyclase Associated Protein 1 Elisa Kit (CAP1)anti-CAP1anti-CAP1anti-CAP1anti-CAP1anti-CAP1 Related articles to: PA_FB_W w_o cap1
- Elucidating the molecular mechanisms underlying ammonium (NH)-mediated root system development is critical for alleviating NH toxicity in plants. The Arabidopsis thaliana [Ca]-associated protein kinase CAP1 regulates root hair growth in response to NH treatment, with the cap1-1 mutant exhibiting hypersensitivity to NH and elevated reactive oxygen species (ROS) levels. Based on our previous phosphoproteomic data, here we investigated the role of Respiratory Burst Oxidase Homolog D (AtRBOHD) in CAP1-mediated root hair growth under NH treatment. Through yeast two-hybrid (Y2H), bimolecular fluorescence complementation (BiFC), co-immunoprecipitation (Co-IP), and in vitro phosphorylation assays, we demonstrate that CAP1 physically interacts with and phosphorylates RBOHD, with Ser347 identified as a critical phosphorylation site in RBOHD that is required for their interaction. Genetic complementation assays revealed that expressing either wild-type RBOHD or its phospho-mimetic variant (RBOHD) partially restored root hair growth in cap1-1 mutants while reducing ROS levels to those of the wild type under NH treatment. Collectively, our findings establish a mechanistic model in which CAP1 phosphorylates RBOHD at Ser347 to regulate NH-dependent root hair growth by modulating ROS homeostasis. - Source: PubMed
Publication date: 2026/07/17
Yang HongWang LianlianDong YichenDu JiashunChen Qing-BinZhou YunMa XiaonanBai Ling - Pulmonary arterial hypertension (PAH) is driven by maladaptive endothelial remodeling, but the transcriptional regulators that couple proliferative stress to arterialized endothelial states remain incompletely defined. E2F transcription factor 1 (E2F1) is classically viewed as a cell-cycle regulator; whether E2F1 functions as a disease-driving node that promotes endothelial arterial programming in PAH remains unknown. - Source: PubMed
Publication date: 2026/07/07
Yi DanTripathi AnkitZheng QiLiu BinCao Susie WeizhiKoenitzer Jeffrey RShen MengchengFallon Michael BDai Zhiyu - Obsessive-compulsive disorder (OCD) has been associated with abnormal large-scale brain network dynamics, but its transient whole-brain co-activation states remain insufficiently characterized. Against this background, the current study investigated potential alterations in the dynamics of whole-brain co-activation pattern (CAP) in OCD. - Source: PubMed
Publication date: 2026/07/14
Chang YangeRuan HanyangKoch Kathrin - The Tibetan Plateau, the Earth's highest and largest plateau, has a harsh environment for agriculture, and is a global biodiversity hotspot, raising the challenge of simultaneously satisfying food production and conservation goals. Currently, agriculture involves crop production on steep slopes and overgrazing, which threatens future productivity. The Tibetan Plateau is also undergoing climate change. We evaluate food production from 1990 to 2020 and use these results to model future trends and risks to food production on the Tibetan Plateau. We assess the feasibility of achieving both food production and conservation goals simultaneously under climate change scenarios. Food production increased 32.33% over three decades, providing 2,892.98 kcal d cap, more than enough to satisfy food self-sufficiency. Under climate change, the Tibetan Plateau will become warmer and wetter under Shared Socioeconomic Pathways (SSPs) SSP126, SSP245, and SSP585, which combined with agricultural advances (e.g., improved mechanization and irrigation), will likely result in increased yields even with a 10% reduction in cropland area-greater than the total area of all steeply sloping cropland, thereby allowing retirement of steeply sloping cropland and livestock reductions while still meeting food production goals. Meanwhile, key ecosystem services, including carbon sequestration, water retention, and habitat quality, are also projected to improve substantially. Nonetheless, the increasing frequency and severity of extreme weather events are expected to reduce food production, undermine current dietary requirements and may threaten the minimum nutritional intake required for humans. - Source: PubMed
Publication date: 2026/07/08
Wang LijingPolasky StephenLu FeiMiller Colleen RYing LingxiaoXiao YiOuyang Zhiyun - Breeding for cold tolerance in pepper (Capsicum annuum L.) is critical to mitigate yield losses caused by unpredictable temperature fluctuations associated with climate change. However, genetic improvement of this trait is hindered by challenges in accurate phenotyping, particularly at the adult stage, and by its complex genetic architecture involving numerous minor-effect loci. While genomic selection (GS) offers a promising solution to accelerate genetic gain, its predictive ability is often limited by statistical noise from uninformative markers within whole-genome marker sets. This study aimed to overcome this limitation by developing a robust phenotypic index and implementing a genome-wide association study (GWAS)-informed GS strategy. - Source: PubMed
Publication date: 2026/07/07
Lee KyeongseokKim Geon WooJeong Hee-JinJeong Hyeon-SeokKwon Jin-KyungKang Byoung-Cheorl