Chemerin _ TIG2 (145_157)(Human) _ 100ug
- Known as:
- Chemerin _ TIG2 (145_157)(Human) _ 100ug
- Catalog number:
- 002-50
- Product Quantity:
- 100 µg
- Category:
- -
- Supplier:
- Phoenix Peptide
- Gene target:
- Chemerin _ TIG2 (145_157)(Human) 100ug
Related genes to: Chemerin _ TIG2 (145_157)(Human) _ 100ug
- Gene:
- RARRES2 NIH gene
- Name:
- retinoic acid receptor responder 2
- Previous symbol:
- -
- Synonyms:
- TIG2, HP10433
- Chromosome:
- 7q36.1
- Locus Type:
- gene with protein product
- Date approved:
- 1998-02-03
- Date modifiied:
- 2016-03-15
Related products to: Chemerin _ TIG2 (145_157)(Human) _ 100ug
Related articles to: Chemerin _ TIG2 (145_157)(Human) _ 100ug
- This study aimed to elucidate chemerin's role in gestational diabetes mellitus (GDM)-related fetal endothelial dysfunction and its association with non-invasive hemodynamic parameters. - Source: PubMed
Zeng ShilinWang HongyingYang WanyingZeng YuzhouShenTu WeihuiFang Yi - Single-cell fixed RNA profiling (FLEX) is a novel technique that captures RNA expression in frozen tissues at a single-cell resolution. We applied FLEX to mouse model of liver fibrosis progression and regression to identify novel antifibrotic targets. - Source: PubMed
Publication date: 2026/02/11
Duc Pham MinhThuy Le Thi ThanhHai HoangVan Bao TranHa Nguyen ThiAnh Pham TuanIkenaga HirokoFujii HidekiYoshida KanakoEnomoto MasaruUchida-Kobayashi SawakoYuasa HidetoMatsubara TsutomuHuyen Vu ThuongCheng YiYamagishi RyotaOhtani NaokoOikawa DaisukeTokunaga FuminoriKisseleva TatianaBrenner David AIwakiri YasukoGracia-Sancho JordiKawada Norifumi - Chemerin (RARRES2) is a multifunctional adipokine widely implicated in metabolic, inflammatory, cardiovascular, and neoplastic diseases, yet its clinical interpretation remains confounded by reliance on "total chemerin" measurements that obscure its proteoform-specific signaling. This single value is mechanistically misleading because chemerin is secreted as an inactive precursor and undergoes extracellular proteolytic processing into C-terminal isoforms with graded receptor potency and compartment-specific distribution. This review decodes chemerin's functional duality through three integrated layers: (1) protease-encoded isoform "barcodes" that dictate bioactivity, (2) compartment-specific isoform landscapes in human biofluids and disease microenvironments, and (3) receptor context across CMKLR1, GPR1, and CCRL2 that shapes signaling output. We provide a conceptual roadmap for translating chemerin biology, emphasizing isoform-resolved quantification via targeted /MRM-MS and a compartment-aware framework for interpreting clinical associations. This framework helps interpret heterogeneous disease associations and highlights testable entry points for context-specific targeting. - Source: PubMed
Publication date: 2026/03/06
Wang JingDeng JiangmingXiao TingMeng Wen - The pathogenesis of aortic aneurysm (AA) remains unclear, and there are no effective therapeutic drugs or targets. Circulating plasma proteins are considered biomarkers of AA and potential therapeutic targets for AA. This study aimed to systematically evaluate the causal effects of plasma proteins on AA using a multi-cohort Mendelian randomization (MR) approach. - Source: PubMed
Publication date: 2026/03/25
Ding MeizhuLi YinggaoYao ShashaWang Kan - Chemerin is a recently identified adipokine implicated in appetite regulation and energy metabolism. This study aimed to investigate the relationship between serum chemerin levels, nutritional status, and appetitive traits in early childhood. This cross-sectional study included 85 children aged 2-9 years. Appetite-related traits were assessed using the Child Eating Behavior Questionnaire (CEBQ). Anthropometric measurements were obtained, and fasting venous blood samples were collected for biochemical analyses, including serum chemerin levels. Based on the CEBQ results, participants with a food approach score below 39.50 and a food avoidant score above 58.50 were classified as having appetite-related undernutrition (n = 44) and the others as normal appetite (n = 41). Biochemical and anthropometric parameters, as well as chemerin levels, were compared between the two groups. In addition, correlation analyses were conducted to examine the relationships between chemerin levels and biochemical parameters, anthropometric measurements, and CEBQ scores. Serum chemerin concentrations were significantly lower in children with appetite-related undernutrition compared with those with normal appetite (median [IQR] 562.4 [12.6-946.6] vs. 1264.9 [976.3-1765.0] ng/L, p < 0.05). Chemerin levels were positively correlated with food approach traits and inversely correlated with food avoidance traits. Moreover, positive associations were observed with LDL cholesterol, total cholesterol, albumin, and calcium levels. - Source: PubMed
Publication date: 2026/03/15
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