SP 9155 (401_433)(Mouse) _ 100ug
- Known as:
- SP 9155 (401_433)(Mouse) _ 100ug
- Catalog number:
- 001-46
- Product Quantity:
- 100 µg
- Category:
- -
- Supplier:
- Phoenix Peptide
- Gene target:
- 9155 (401_433)(Mouse) _ 100ug
Related genes to: SP 9155 (401_433)(Mouse) _ 100ug
- Gene:
- EGFLAM NIH gene
- Name:
- EGF like, fibronectin type III and laminin G domains
- Previous symbol:
- -
- Synonyms:
- FLJ39155, AGRINL, AGRNL, PIKA
- Chromosome:
- 5p13.2-p13.1
- Locus Type:
- gene with protein product
- Date approved:
- 2006-07-19
- Date modifiied:
- 2018-02-13
Related products to: SP 9155 (401_433)(Mouse) _ 100ug
Related articles to: SP 9155 (401_433)(Mouse) _ 100ug
- Observational studies suggest an association between Coronavirus Disease 2019 (COVID-19) and polymyositis (PM), but causal inference s limited by confounding. This study adopted a multilevel exploratory framework to investigate potential relationships. We used two-sample Mendelian randomization (MR) to assess the causal effect of severe COVID-19 on PM, multi-omic analyses to screen for potential mediators, and retrospectively compared hematological profiles between severe and non-sever COVID-19 cases. - Source: PubMed
Publication date: 2026/04/09
Chen MiaomiaoLi HongmeiTong XiaZhang Xin - The prevalence of Type 2 diabetes mellitus (T2DM) is rapidly increasing in India, yet molecular markers that reflect early disease susceptibility remain limited. Epigenetic modifications such as DNA methylation may reflect early metabolic vulnerability preceding overt dysglycemia. In this study, we examined genome-wide DNA methylation patterns in a pilot subset nested within a prospective Indian cohort using Nanopore sequencing and assessed their associations with previously identified metabolite predictors from the same cohort. - Source: PubMed
Publication date: 2026/04/16
Satheesh GopikaAsokan Aneesh KVijayakumar GadadharanRajavelu ArumugamRao Sudha NarayanaSivakumar Krishnankutty ChandrikaJaleel Abdul - Congenital stationary night blindness (CSNB) is a clinically and genetically heterogeneous inherited retinal disorder (IRD), and in many complete CSNB (cCSNB) cases, the underlying genetic cause remains unknown. Uncovering the genetic defects of IRDs helps to refine diagnostic methods and supports the development of specific therapeutic approaches. - Source: PubMed
Boranijasevic SanjaSmirnov VasilyNavarro JulienTjon-Fo-Sang MarthaCondroyer ChristelHaer-Wigman LonnekeAntonio AlineDhaenens Claire-MarieVerhoeven Virginie J MSahel José-Alainvan den Born L IngeborghDefoort SabineAudo IsabelleZeitz Christina - EGFLAM is a versatile protein widely expressed in multiple human tissues, yet its function in pan-cancer is not fully understood. To investigate the molecular function of EGFLAM, a comprehensive pan-cancer analysis was carried out using several public databases and bioinformatics tools. Ultimately, confirmatory experiments were conducted in vitro with gastric cancer cell lines. The results showed that EGFLAM expression was elevated in multiple cancer types, especially gastric cancer. It also demonstrated prognostic predictive value in several cancer types, suggesting its potential as a prognostic biomarker. The dysregulation of EGFLAM expression observed in certain cancers might be attributed to factors such as promoter methylation changes, mRNA methylation modifications, and genetic alterations of the EGFLAM locus. EGFLAM expression was associated with Immune cell infiltration, immune checkpoints, tumor mutation burden (TMB), and microsatellite instability (MSI). Single-cell analysis of gastric cancer showed that EGFLAM was predominantly expressed in fibroblast populations. Functional enrichment analyses (GO/KEGG) demonstrated EGFLAM involvement in extracellular matrix receptor interactions and PI3K-AKT signaling pathway. RT‒qPCR confirmed EGFLAM upregulation in gastric cancer specimens compared to normal controls. In vitro functional assays revealed that EGFLAM knockdown significantly suppressed gastric cancer cell proliferation, migration, and invasion while inducing apoptosis. Collectively, our multi-omics analyses delineated EGFLAM's oncogenic functions across cancer types, positioning it as both a promising prognostic biomarker and a potential therapeutic target for gastric cancer. - Source: PubMed
Publication date: 2025/07/01
Yang JianXu WenqianWang ShengyuYu ZhuFeng YueLi DaChen Junqiang - Neutrophil trap (NET) is an important feature of chronic inflammatory diseases. At present, there are still few studies to explore the characteristics of NET in different chronic obstructive pulmonary disease (COPD) patients. This study aimed to identify NET signature genes in different COPD patients. - Source: PubMed
Publication date: 2025/04/25
Yu JiaXiao TiantianPan YunHe YangshenTan Jiaxiong