SARS Nucleocapsid
- Known as:
- SARS Nucleocapsid
- Catalog number:
- ANT-180
- Product Quantity:
- 100µg
- Category:
- -
- Supplier:
- Prospecbio
- Gene target:
- SARS Nucleocapsid
Related genes to: SARS Nucleocapsid
- Gene:
- SARS NIH gene
- Name:
- seryl-tRNA synthetase
- Previous symbol:
- -
- Synonyms:
- SERS
- Chromosome:
- 1p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1995-06-09
- Date modifiied:
- 2014-11-18
- Gene:
- SARS2 NIH gene
- Name:
- seryl-tRNA synthetase 2, mitochondrial
- Previous symbol:
- SARSM
- Synonyms:
- FLJ20450, mtSerRS, SerRSmt, SARS, SERS, SYS
- Chromosome:
- 19q13.2
- Locus Type:
- gene with protein product
- Date approved:
- 2002-10-09
- Date modifiied:
- 2016-11-09
Related products to: SARS Nucleocapsid
62 kDa RNA-binding protein,Oryctolagus cuniculus,Rabbit,SARS,Serine--tRNA ligase,SerRS,SERS,Seryl-tRNA synthetase, cytoplasmic,Seryl-tRNA(Ser_Sec) synthetaseSARS coronavirus N Protein monoclonal antibody, clone 38j4SARS coronavirus N Protein monoclonal antibody, clone 8k5hA' SARS-CoV, Spike Antibody (OAMA02852)A' SARS-CoV, Spike Antibody (OAMA02863)A'SARS-CoV, M protein (NT) antibodyA'SARS-CoV, M protein (NT) antibody Polyclonal Antibodies Primary antibodiesA'SARS-CoV, M protein (NT) antibody Polyclonal Antibody Host: RabbitACE2 (SARS Receptor) Antibody (C-term)ACE2 (SARS Receptor) Antibody (C-term)ACE2 (SARS Receptor) Antibody (C-term) Blocking PeptideACE2 (SARS Receptor) Antibody (C-term) Blocking PeptideACE2 (SARS Receptor) Antibody (C-term) Purified Rabbit Polyclonal Antibody (Pab) Applications WB, IHC, EACE2 (SARS Receptor) Antibody (C-term) Purified Rabbit Polyclonal Antibody (Pab) Applications WB, IHC, EACE2 (SARS Receptor) Antibody (Center) Related articles to: SARS Nucleocapsid
- Missing data can pose fundamental challenges to statistical inference, with nonignorable missing or missing not at random (MNAR) presenting the most severe methodological difficulties. Despite substantial advances in MNAR inference methods, several limitations remain. These generally include interpretability issues, non-identifiability, unverifiable parametric assumptions, and reliance on external information for which clear practical guidance is often lacking-particularly in sensitivity and Bayesian methods. In this paper, motivated by a real-world COVID-19 dataset from the Centers for Disease Control and Prevention (CDC), we study an MNAR scenario in the presence of a shadow variable that may itself also be subject to MNAR. A shadow variable is associated with the primary variable that is MNAR, but is conditionally independent of that variable's missingness given the primary variable and other covariates. Under the pattern mixture model framework, we propose a nonparametric inference method that can leverage external data to explicitly address the identification and estimation problems in the primary data. The method requires inference only of an observed data density and an odds of missing function, with the latter forming the core of our approach. We further provide two multiple-imputation-based estimation strategies, enhancing transparency and interpretability. The proposed framework can accommodate both covariate MNAR and outcome MNAR settings, as well as different variable types, and extends the existing shadow variable paradigm for MNAR data by relaxing the common assumption that the shadow variable must be fully observed. We evaluate the proposed method through simulation studies and apply it to CDC COVID-19 surveillance data. - Source: PubMed
Zhou WenxiaoFu Bo - Infectious complications are a major cause of morbidity and non-relapse mortality after CAR-T cell therapy. Respiratory viral infections (RVIs) are frequent, yet their incidence, timing, and immune correlates remain incompletely defined. - Source: PubMed
Publication date: 2026/09/27
Einarsdottir SigrunFei TengSotelo-Alva Maria IsabelGomez-Llobell MarinaEscribano-Serrat SilviaShi KayleenBeyar-Katz OfratBhamidipati DedipyaCorona MagdalenaFalchi LorenzoGeva MikaHalloun JabourHultcrantz MalinIsraeli SapirKhatib HazimKamboj MiniMailankody ShamPapanicolaou GenovefaPalomba M LiaPark Jae HRaj SandeepScordo MichaelSalles GillesSeo Susan KShah GunjanShibli NiveenArya SwarnValtis YannisSanz JaimeRejeski KaiUsmani SaadPerales Miguel-AngelShouval RoniShahid Zainab - Traditional Chinese medicines (TCMs) are rich sources of structurally diverse bioactive compounds, yet rapid identification of protease inhibitors from complex botanical matrices remains challenging. Here, a magnetic bead-based affinity-fishing platform coupled with UPLC-Q-Exactive-Orbitrap-MS/MS was applied to identify SARS-CoV-2 main protease (M) inhibitors from Reynoutria japonica. The crude ethanolic extract inhibited M with an IC of 44.92 ± 2.31 µg/mL. M-functionalized magnetic beads enriched eight constituents, which were identified by high-resolution mass spectrometry and evaluated using a FRET-based inhibition assay. Six compounds showed concentration-dependent activity, with resveratrol being the most potent (IC = 34.01 ± 1.67 µmol/L), followed by glycitein, genistein, emodin, apigenin-7-O-glucoside, and biochanin A. HPLC-DAD further quantified the principal active constituents. Molecular docking suggested interactions with residues in the Mpro substrate-binding pocket, while network pharmacology predicted associations with host-related targets involving IL6, TNF, and AKT1. Overall, this workflow enables efficient enrichment, structural identification, and functional prioritization of M-inhibitory constituents from complex botanical extracts, providing a practical strategy for target-directed natural product discovery. - Source: PubMed
Huang YujingTian ChenjingGu ZhipengLiang JinlianZu DuntaoYang JianniZhang WanrongRen NinaZheng Junxia - Long-term genomic surveillance of SARS-CoV-2 remains important as routine clinical testing and sequencing decline over time after the pandemic. We describe the temporal dynamics, methodological adaptation, and operational continuity of Italy's national wastewater variant surveillance from October 2021 to December 2025. Across 51 monthly surveys, 6,278 wastewater samples collected from 167 wastewater treatment plants in 18 Regions and 2 Autonomous Provinces were analysed by RT-qPCR and targeted spike sequencing using short- and long-amplicon Sanger and Oxford Nanopore Technology approaches. Overall, 1,186 samples yielded a successful long amplicon and an interpretable Sanger sequence, while 248 regional pools were characterized by ONT during the funded surveillance phase from October 2021 to March 2023. The data documented the replacement of Delta by Omicron, followed by the circulation of BA.1*, BA.2* and BA.4/BA.5* and the subsequent emergence of BQ*, XBB*, EG.5*, and JN.1* lineages, with periods of persistence and co-circulation. The analytical workflow was adapted as lineage-defining mutations changed. Since March 2023, surveillance continued voluntarily through December 2025 using only long-amplicon Sanger sequencing. A qualitative comparison with national periodic flash surveys to estimate the prevalence of SARS-CoV-2 variants on biological samples showed that the two systems broadly captured the same succession of major lineage transitions, although the variant prevalence estimates and wastewater lineage proportions were not directly comparable. These findings support the feasibility of a targeted and adaptable strategy for sustaining nationwide wastewater genomic surveillance across emergency and post-emergency phases and for complementing clinical surveillance when routine testing and sequencing are reduced. - Source: PubMed
Publication date: 2026/09/27
Veneri CBonanno Ferraro GMancini PBrandtner DIaconelli MCongiu DFranco ALucentini LDel Giudice CRossi MD'Avenio GStefanelli PAmbrosio LMammone ASuffredini E La Rosa G - Older Latinos participate in low levels of physical activity (PA), despite it being a protective factor against chronic diseases, like Alzheimer's disease and related dementias . PA interventions, like the BAILAMOS™ dance program and ¡En Forma y Fuerte! (Fit & Strong!®) exercise program, were created to address a lack of culturally relevant PA programs for older Latinos. The COVID-19 pandemic allowed for these in-person PA interventions to be adapted for remote delivery. The Cognitive Enhancement and Risk-Reduction through Exercise for Brain-Related Outcomes study examined the feasibility and impact of BAILAMOS™ and ¡En Forma y Fuerte! delivered remotely to inactive older Latinos with memory concerns. - Source: PubMed
Ocampo-Mota JocelynPadilla DayaneKarlinsey Skidmore BrynneCardiel EduardoKhanna SonamPinto MarianaMarquez David X