FTCD
- Known as:
- FTCD
- Catalog number:
- ENZ-302
- Product Quantity:
- 5µg
- Category:
- -
- Supplier:
- Prospecbio
- Gene target:
- FTCD
Related genes to: FTCD
- Gene:
- FTCD NIH gene
- Name:
- formimidoyltransferase cyclodeaminase
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 21q22.3
- Locus Type:
- gene with protein product
- Date approved:
- 1999-07-23
- Date modifiied:
- 2015-08-25
Related products to: FTCD
Related articles to: FTCD
- Background Tobacco use continues to be a significant global public health issue, causing over 8 million deaths each year. People with mental health conditions face a higher risk, and new nicotine products have increased the complexity of the challenge. Despite this, there is limited information on psychological distress, nicotine dependence, and quality of life among cigarette and e-cigarette users. Objective The primary objective of this study was to compare psychological distress and quality of life among cigarette smokers, e-cigarette users, and non-smokers in Jeddah, Saudi Arabia. The secondary objective was to examine the association between nicotine dependence severity and psychological distress and quality of life among cigarette smokers and e-cigarette users. Methods A cross-sectional study was conducted among 368 adults (≥18 years) living in Jeddah from April to June 2026. Participants were recruited using stratified quota convenience sampling through online distribution via Telegram and WhatsApp applications, and community networks. The participants were divided into three groups: cigarette smokers (n=117), e-cigarette users (n=95), and non-smokers (n=156). Data were collected using a self-administered questionnaire covering sociodemographics, smoking history, psychological distress (K6), quality of life (World Health Organization Quality of Life - Brief Version (WHOQOL-BREF)), and nicotine dependence (Fagerström Test for Nicotine Dependence (FTND)/electronic Fagerström Test for Cigarette Dependence (e-FTCD)). Results Non-smokers scored higher than both smoking groups on most WHOQOL-BREF domains (p < 0.05). The mean K6 score was 15.20 (SD = 5.67), and 64.9% of participants screened positive for serious psychological distress. The proportion of serious psychological distress did not differ significantly by smoking status (p = 0.111). Among cigarette smokers and e-cigarette users, nicotine dependence severity showed a significant non-linear association with psychological distress (p = 0.001 and p = 0.004, respectively). Conclusion Non-smokers had higher WHOQOL-BREF scores than cigarette smokers and e-cigarette users on most domains. Although 64.9% of participants screened positive for serious psychological distress, this finding should be interpreted cautiously given the convenience sampling approach and may not be generalizable to the broader population. Further research is needed to clarify the relationship between nicotine dependence, psychological distress, and quality of life and to assess the potential implications for tobacco cessation and mental health interventions in Saudi Arabia. - Source: PubMed
Publication date: 2026/08/26
Yahya Farah AAlnemari Reem FAlahmari AsmaAlghamdi Saad A - Although language production is generally dominated by the left hemisphere, it remains uncertain whether the script format influences the degree of this lateralization. To examine this issue, verbal fluency was assessed in 96 right-handed native Chinese speakers using functional transcranial Doppler sonography (fTCD). The subjects were asked to perform four overt word-generation tasks with four combinations of cue format and fluency type: Pinyin phonological fluency, character phonological fluency, Pinyin semantic fluency, and character semantic fluency. Laterality indices were calculated as the mean left-minus-right middle cerebral artery blood-flow velocity difference across the complete prespecified period of interest from 4 to 14 s after cue onset. All four conditions showed significant left lateralization, with mean LIs of 3.05, 2.60, 2.76, and 2.26 for Pinyin phonological, character phonological, Pinyin semantic, and character semantic fluency, respectively; all ps < .001. Pinyin-cued tasks yielded greater lateralization than character-cued tasks, F(1, 95) = 117.61, < .001, ηp² = .553, and phonological fluency yielded greater lateralization than semantic fluency, F(1, 95) = 32.81, < .001, ηp² = .257. The results indicate that verbal fluency is left-dominant in Mandarin, while the script format modulates the degree of hemispheric dominance during lexical retrieval. - Source: PubMed
Publication date: 2026/09/19
Abdelsattar Hager AhmedKhan Sumbul Asad - The Heaviness of Smoking Index (HSI) is a brief tool for assessing nicotine addiction. This study evaluated the agreement and classification performance of the HSI relative to the Fagerström Test for Cigarette Dependence (FTCD). - Source: PubMed
Publication date: 2026/08/25
Charkazi AbdurrahmanHosseini Seyed GhadirDehghan HajarForoughi ArezouPahlavanzadeh Bagher - Metabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous condition where overlapping cardiometabolic risk factors challenge accurate prognostic prediction. - Source: PubMed
Publication date: 2026/07/29
Diambra LuisSookoian SilviaPirola Carlos Jose - Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a late-onset neurodegenerative disorder caused by FMR1 premutation CGG repeat expansions (55-200 repeats). The epigenetic landscape of the FXTAS brain remains uncharacterized. We performed genome-wide DNA methylation profiling of postmortem prefrontal cortex tissue to identify differentially methylated positions (DMPs) and candidate genes, and sought protein-level support for a neuroinflammatory signal. - Source: PubMed
Publication date: 2026/07/10
Lozano ReymundoLin XiaoHagerman RandiCerdeño Verónica MartínezPinto Dalila