Aven Rabbit Polyclonal Antibody
- Known as:
- Aven Rabbit Polyclonal Antibody
- Catalog number:
- APO-2417
- Product Quantity:
- 0.1 mg
- Category:
- -
- Supplier:
- Zyagen
- Gene target:
- Aven Rabbit Polyclonal Antibody
Related genes to: Aven Rabbit Polyclonal Antibody
- Gene:
- AVEN NIH gene
- Name:
- apoptosis and caspase activation inhibitor
- Previous symbol:
- -
- Synonyms:
- PDCD12
- Chromosome:
- 15q14
- Locus Type:
- gene with protein product
- Date approved:
- 2002-09-17
- Date modifiied:
- 2016-10-05
Related products to: Aven Rabbit Polyclonal Antibody
Related articles to: Aven Rabbit Polyclonal Antibody
- To assess the real-world performance of the Serial Clinical Observation (SCO) strategy in identifying and treating Early-Onset Sepsis (EOS) cases, and to compare it with the recommendations the Neonatal Sepsis Calculator (NSC) would have provided. This multicentre study analyzed prospectively culture-confirmed EOS cases caused by Group B Streptococcus (GBS) or Escherichia coli (2016-2022) in term and late-preterm infants managed with the SCO approach in Italy. We evaluated the proportion of infants assigned to routine care at birth and the time to antibiotics. NSC scores at 4, 12, and 24 h after birth were retrospectively calculated. Of 57 EOS cases, 23 (40.4%) had no maternal risk factors. Fifty infants developed clinical signs of illness either at birth (n = 24) or postnatally (n = 26). Among those symptomatic at birth, the median time to antibiotic initiation was 2.0 h (IQR 1.0-5.75). "Major" clinical signs according to the SCO protocol were present in 79.2%, prompting immediate antibiotics. Retrospective NSC application at 4 h would have recommended antibiotics in 87.5%. Of the 26 who became symptomatic after birth, 16 (61.5%) were assigned to routine care. The median time from disease onset to treatment was 6.0 h (IQR 2.0-14.0). At 4 h, NSC would have assigned 19 (73.1%) of these infants to routine care. Subtle neurological signs (i.e. hypotonia, irritability, altered consciousness) were frequently observed at onset in infants who developed severe disease. - Source: PubMed
Publication date: 2026/04/16
Miselli FrancescaLugli LiciaDragone GiorgiaBedetti LucaSpinedi SofiaCapretti MariagraziaMarrozzini LuciaDi Luca LuisaFanaro SilviaGambini LuciaBiasucci GiacomoPiccinini GiancarloScarponi DavidePapa IreneNanni FrancescaBaroni LorenzaPagano RossellaCapone ValeriaBerardi Alberto - Powdery mildews from the genus infect economically significant crops such as strawberries ( ×) and raspberries (). Until recently, these powdery mildews have been assigned to , which represents a complex of species. In the present analysis, selected taxa within s. lat. have been subjected to morphological and ITS+28S rDNA phylogenetic examinations. We demonstrated that the powdery mildews on and spp. do not pertain to s. str. The new combination (≡ ) is introduced for the powdery mildew on ×, spp. and . is widespread in Asia and Europe, however, sequences obtained from specimens collected in South and North America belong to an unresolved group. All sequences obtained from specimens of powdery mildew on spp. group together in the phylogenetic tree. This suggests a separate species on spp. for which the new combination (≡ ) is introduced. sp. nov. is introduced for powdery mildews from western North America infecting and . Additionally, sp. nov. is introduced for powdery mildews in North America infecting spp. and . - Source: PubMed
Publication date: 2025/07/01
Bradshaw MichaelLiu MiaoCrouch UmaThomas JacklynShoukouhi ParivashJin Dan-NiLiu Shu-YanPaul AndrewBraun Uwe - Many individuals who initially present with depression later develop manic or hypomanic episodes, yet the biological processes accompanying this delayed shift remain unclear. Here, we examined whether perturbation of the adult hippocampal neurogenic niche is associated with time-dependent shifts in mood-relevant behaviors. Using Nestin-CreER::Rosa26-FloxedSTOP-DTa (Nestin-DTa) mice, we induced partial ablation of Nestin-positive adult neural stem cells (aNSCs) in the hippocampus by tamoxifen administration and assessed phenotypes at 4 and 8 weeks post-ablation. Neurogenic-lineage populations in the dentate gyrus were quantified by immunohistochemistry using stage-specific markers. Partial aNSC ablation reduced the Nestin-positive pool and BrdU-labeled proliferation, followed by a compensatory expansion of proliferative progenitors and DCX-positive neuroblasts. At 4 weeks, Nestin-DTa mice exhibited anxiety-like behavior and increased forced-swim immobility. By 8 weeks, anxiety-like measures normalized, and mice displayed increased exploratory/locomotor activity and reduced forced-swim immobility, accompanied by sustained elevation of progenitor and immature neuronal compartments. These findings provide a tractable model in which disruption of the adult neurogenic niche is associated with a transition from depression-like behavior to a hyperactive, mania-like phenotype over time. - Source: PubMed
Publication date: 2026/04/08
Song JieunKim WoonryongPark YoojinLee Ja-MyongKim Jong-HoonPark Dong-HyukLee Heon-JeongShin Ki-SoonKim Hyun JungGeum Dongho - Today, there is no authoritative accepted definition of safety science, although, empirically, delineations can be drawn based on the papers published in safety science journals. The meaning, object, and scope of safety science have been extensively discussed by leading scholars in recent years. The present paper aims to contribute to this discussion by clarifying safety science's foundation and relationship to risk science. The paper argues that there is a potential for further enhancement of the understanding, assessment, communication, and handling of safety issues by a stronger interaction with risk science, both generic and applied risk science. Safety science is concerned with topics which all relate to risk, yet we often see safety science literature on such topics without addressing risk. A main conclusion of the paper is that safety science can be included in risk science, with the main topics as part of applied risk science but also contributions to generic, fundamental risk science. - Source: PubMed
Aven Terje - Pneumonia is a leading cause of morbidity and mortality in older adults, and antidepressant use is increasing globally. Although biologically plausible links exist, comprehensive, population-based evidence remains limited. We evaluated the association of antidepressant use with pneumonia hospitalisation and potential effect modifiers. - Source: PubMed
Jeon JinyoungGeum Min JungAh Young-MiLee Hyun WooYu Yun Mi