Guinea pig Apolipoprotein H ELISA, APOH
- Known as:
- Guinea pig Apolipoprotein H Enzyme-linked immunosorbent assay test, APOH
- Catalog number:
- E05A0521
- Category:
- -
- Supplier:
- Blue Gene Biotech
- Gene target:
- Guinea pig Apolipoprotein ELISA APOH
Related genes to: Guinea pig Apolipoprotein H ELISA, APOH
- Gene:
- APOH NIH gene
- Name:
- apolipoprotein H
- Previous symbol:
- B2G1
- Synonyms:
- BG
- Chromosome:
- 17q24.2
- Locus Type:
- gene with protein product
- Date approved:
- 1987-09-11
- Date modifiied:
- 2015-12-17
Related products to: Guinea pig Apolipoprotein H ELISA, APOH
Related articles to: Guinea pig Apolipoprotein H ELISA, APOH
- Lipoproteins are molecules composed of phospholipids and apolipoproteins that transport triacylglycerol and cholesterol in blood and are implicated in the development of many diseases. - Source: PubMed
Publication date: 2026/07/14
Łukaszuk BartłomiejChabowski AdrianZiemba AndrzejChoromańska BarbaraMyśliwiec PiotrSupruniuk KatarzynaMikłosz Agnieszka - Chronic kidney disease (CKD) is a major health burden, yet its underlying mechanisms and early predictors remain poorly understood. - Source: PubMed
Publication date: 2026/07/09
Ru DongmeiWang XinyueXiao CongmeiCheng ManjingZhou FuxianMamuti ReziwanguliXi YueDeng KuiWang JiaoXu LinZheng Ju-ShengChen Yu-Ming - Cetaceans face the risk of thromboembolism due to diving and decompression responses. However, cetaceans maintain normal blood circulation. This study explores the molecular mechanisms cetaceans use to mitigate diving-associated hemostatic challenges during diving. Forty-six species were analyzed, including 18 cetaceans, 9 artiodactyls, and 19 other terrestrial mammals. Thirty-nine anticoagulant genes and proteins were examined, identifying 6 genes (ANXA2, ANXA5, FGA, FGB, PLAUR, and PLG) with conserved evolution, 4 genes (ANXA2, PDGFB, SH2B3, THBS1) with positive selection, and 12 proteins (APOH, FGA, FGB, FGG, GP1BA, PLAU, PRKCD, PRKG1, SERPINF2, SERPING1, TMPRSS6, and TMX1) with specific amino acid sites in cetaceans. Ancestral state reconstruction revealed independent evolution of deep diving behavior in different cetacean lineages, particularly within Odontoceti. Correlation analysis linked the evolution of the APOE gene with diving depth, suggesting its role in diving adaptation. These analyses suggest that cetaceans may help reduce the risk of thrombosis during diving by lowering platelet activity, enhancing fibrinolysis, and modulating the coagulation cascade. These analyses suggest that cetaceans may mitigate diving-associated thrombotic risk by modulating platelet activity, fibrinolysis, and the coagulation cascade. Overall, this study identifies candidate anticoagulant-related genes and amino acid substitutions for future functional validation of hemostatic adaptation in cetaceans. - Source: PubMed
Publication date: 2026/07/06
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