Antigens G-CSF, Human, Recombinant, E.coli
- Known as:
- Antigens G-CSF, Human, Recombinant, E.coli
- Catalog number:
- 01-2237
- Product Quantity:
- 5
- Category:
- -
- Supplier:
- ARP
- Gene target:
- Antigens G-CSF Human Recombinant .coli
Related genes to: Antigens G-CSF, Human, Recombinant, E.coli
- Gene:
- CSF3 NIH gene
- Name:
- colony stimulating factor 3
- Previous symbol:
- GCSF, G-CSF, C17orf33
- Synonyms:
- MGC45931
- Chromosome:
- 17q21.1
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-22
- Date modifiied:
- 2016-10-05
- Gene:
- CSF3R NIH gene
- Name:
- colony stimulating factor 3 receptor
- Previous symbol:
- CD114
- Synonyms:
- GCSFR
- Chromosome:
- 1p34.3
- Locus Type:
- gene with protein product
- Date approved:
- 1990-12-10
- Date modifiied:
- 2019-04-23
- Gene:
- FCN2 NIH gene
- Name:
- ficolin 2
- Previous symbol:
- -
- Synonyms:
- P35, FCNL, EBP-37, ficolin-2
- Chromosome:
- 9q34.3
- Locus Type:
- gene with protein product
- Date approved:
- 1996-07-11
- Date modifiied:
- 2016-10-05
Related products to: Antigens G-CSF, Human, Recombinant, E.coli
Related articles to: Antigens G-CSF, Human, Recombinant, E.coli
- Preschool wheeze is heterogeneous and only a subset of children progresses to persistent asthma. We hypothesized that early-life wheeze reflects divergent airway epithelial maturation trajectories associated with distinct mucosal immune programs. - Source: PubMed
Publication date: 2026/09/06
Jakwerth Constanze AIlli SabinaCharles HelenOelsner MadlenGabr Amr AZissler Ulrich MErb AnnaFeuerherd MartinDrost FelixBüttner MarenSchubert BenjaminMaison NicoleOmony JimmyWeckmann MarkusGrychtol RuthDittrich Anna-MariaFoth SvenjaSkevaki ChrysanthiTrojan Tobiasvan Koningsbruggen-Rietschel SilkeHansen GesineBahmer ThomasRabe Klaus FBrinkmann FolkeKopp Matthias VolkmarProtzer UlrikeChaker Adam MSchaub Biancavon Mutius ErikaSchmidt-Weber Carsten B - Cardiac sympathetic hyperactivation of the left stellate ganglion (LSG) critically promotes ventricular arrhythmias (VAs) following myocardial infarction (MI). Although neuromodulatory strategies targeting sympathetic activity have shown therapeutic potential, current strategies are limited by invasiveness, incomplete targeting and transient efficacy. Therefore, safe and precise approaches for modulating LSG activity are needed. This study aimed to investigate the enhanced neuromodulatory effects of phospholipid-coated carbon nanotubes (PC-CNTs) combined with near-infrared (NIR) photothermal therapy on the LSG for preventing post-MI VAs. - Source: PubMed
Publication date: 2026/08/31
Xu SaitingZhang NanXu TianyouDeng QiangDai DishaLi XujunZhou LipingZhou Xiaoya - IL-17-producing Type 17 T (T17) cells are central drivers of inflammation in both psoriasis and hidradenitis suppurativa (HS), as evidenced by the clinical efficacy of IL-17-targeting therapies. However, therapeutic responses differ substantially between diseases, raising the possibility that the composition and regulation of T17 states are disease context dependent. - Source: PubMed
Publication date: 2026/08/14
Park NayoungLee JongeunKim DayeonRambhia DarshnaKim JaebumZhou WeiCao JunyueKrueger James GKo YounheeKim Jaehwan - Inflammatory bowel diseases (IBDs) are characterized by chronic intestinal inflammation, in which inflammatory fibroblasts contribute to epithelial damage and amplification of mucosal inflammation. However, the molecular mechanisms regulating their pathogenic activity remain incompletely understood. This study investigated the role of the epigenetic reader BRD4 in the differentiation and function of IL-13RA2-expressing inflammatory fibroblasts in IBD. - Source: PubMed
Frascatani RacheleSerra Mattia AlbertoIannucci AndreaColella MarcoMaresca ClaudiaMarafini IreneLolli ElisabettaSena GiorgiaDivizia AndreaGuida Andrea MartinaSica Giuseppe SigismondoMonteleone Giovanni - Cancer cachexia, affecting up to 80% of patients with advanced cancer, is characterized by metabolic and inflammatory dysregulation driven by tumour- and host-derived factors. Although cytokines are central to cachexia pathogenesis, their circulating profiles and transcriptional relevance across models and sexes remain incompletely defined. We characterized plasma cytokines and skeletal muscle inflammatory signatures in multiple cachexia models, including Lewis Lung Carcinoma (LLC), Colon-26 (C26) and Apc mice. Animals were monitored for 4 weeks (LLC), 25 days (C26) or until ∼20 weeks of age (Apc) per model appropriate endpoints. Publicly available RNA-sequencing datasets from gastrocnemius (LLC) and tibialis anterior (C26 and Apc) muscles were integrated with plasma profiling using a Mouse Cytokine/Chemokine 32-Plex assay. To enhance accessibility and reproducibility, we developed an interactive Shiny application - thecachexiatlas/Cytokine Explorer - enabling dynamic visualization of cytokine levels, transcriptional signatures and phenotype correlations across models and sexes. Cytokine receptor encoding genes (Il6ra, Il4ra, Csf3, Osmr) and inflammatory pathways were consistently enriched in skeletal muscle of cachectic animals across models and sexes. Among circulating cytokines, granulocyte colony-stimulating factor (G-CSF) was uniquely elevated in all models and both sexes. Elevated G-CSF levels exhibited stronger negative correlations with tibialis anterior muscle mass than the commonly used cytokine interleukin (IL)-6, particularly when expressed as the ratio of G-CSF to the anti-inflammatory cytokine IL-13. The G-CSF:IL-13 ratio may represent a robust global biomarker of cachexia severity. The Cytokine Explorer Shiny app provides an open, interactive platform to facilitate hypothesis generation and advance research in cancer cachexia. - Source: PubMed
Publication date: 2026/08/13
Morena FranciellySchrems Eleanor RCabrera Ana ReginaMuhyudin RuqaizaShakeri SepidehTsitkanou StavroulaViggars MarkWashington Tyrone AGreene Nicholas P