SARS Co_V Lysate
- Known as:
- SARS Co_V Lysate
- Catalog number:
- GEN0810035
- Category:
- -
- Supplier:
- Bio-gentaur
- Gene target:
- SARS Co_V Lysate
Related genes to: SARS Co_V Lysate
- Gene:
- SARS NIH gene
- Name:
- seryl-tRNA synthetase
- Previous symbol:
- -
- Synonyms:
- SERS
- Chromosome:
- 1p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1995-06-09
- Date modifiied:
- 2014-11-18
- Gene:
- SARS2 NIH gene
- Name:
- seryl-tRNA synthetase 2, mitochondrial
- Previous symbol:
- SARSM
- Synonyms:
- FLJ20450, mtSerRS, SerRSmt, SARS, SERS, SYS
- Chromosome:
- 19q13.2
- Locus Type:
- gene with protein product
- Date approved:
- 2002-10-09
- Date modifiied:
- 2016-11-09
Related products to: SARS Co_V Lysate
Related articles to: SARS Co_V Lysate
- Talquetamab, a first-in-class G protein-coupled receptor family C group 5 member D (GPRC5D) × CD3 bispecific antibody, demonstrates substantial clinical activity in relapsed/refractory multiple myeloma (RRMM). However, immune dysfunction associated with advanced disease, extensive prior therapies, and bispecific antibody-mediated immune modulation may increase susceptibility to infections. This systematic review and meta-analysis aimed to characterize infection risk associated with talquetamab, with separate evaluation of monotherapy and combination therapy settings. - Source: PubMed
Publication date: 2026/08/19
Huang Zeng-YiWu WeilongLuo GaoyuHuang HuiLiu Xiao-Lian - This study examined the effectiveness of a health literacy (HL) enhancement program in improving awareness of and preventive behaviors related to coronavirus disease 2019 (COVID-19) among older adults in an urban community in Bangkok, Thailand. - Source: PubMed
Publication date: 2026/07/28
Tupanich WalayaAttaworakun SasawanChaiyalap SuteekarnWattanawikan Nattanan - Homogeneous magnetic bioassays for the detection of disease-specific nucleic acids are performed in a "mix & measure" fashion, yet nonenzymatic schemes have picomolar detection limits, which hamper their advancement toward real-world applications. Here, we demonstrate a magnetic omega-loop-mediated dual-signal amplification cascade (MODAC) that combines recycling and duplication of a nucleic acid target and amplifies the magnetic signal gain near-exponentially. We tweak the omega-loop duplex stability by length and sequence variation to achieve a good trade-off between cascade reactivity and leakage. We showcase the nonenzymatic detection of the N gene of SARS-CoV-2 RNA at 23 fM within 90 min at 25 °C. Our validation study with ddPCR demonstrates that the MODAC signal scales linearly with the RNA concentration at low target concentrations. The MODAC tests are performed in nonsterile laboratory settings using a portable magnetic particle spectrometer, highlighting its prospect for point-of-care applications. - Source: PubMed
Sack RebeccaWolgast FlorianCurdts AaronYilmaz YaseminSchilling MeinhardViereck ThiloRand UlfertLak Aidin - Split-aptamer biosensors offer exceptionally low background by assembling only in the presence of a target analyte; however, their performance is frequently limited by the lack of robust design rules for selecting effective split sites. Existing approaches largely rely on heuristic, structure-based assumptions that are poorly validated and often yield suboptimal signal. Herein, we introduce a systematic, data-driven strategy for identifying high-performance split sites within fluorogenic DNA aptamers. Using our massively parallel aptamer performance analyzer platform, we performed comprehensive single- and double-mutant analysis of the DFAME-binding region of the fluorogenic DNA aptamer Lettuce, informed by its three-dimensional structure. Dimensionality reduction and clustering of the resulting sequence-function landscape revealed mutation-tolerant elements within the binding domain that are suitable for splitting while preserving fluorophore activation. Sensors constructed using these nonintuitive split sites, which are unconventional by standard design principles, exhibited a nearly four-fold improvement in the fluorescence signal-to-background ratio for SARS-CoV-2 RNA detection compared to a prior split-Lettuce design. The same split architecture also enabled robust detection of high-pathogenicity H5Nx avian influenza RNA. These results demonstrate that large-scale, data-driven interrogation of aptamer sequence-function relationships can identify nonintuitive split sites and provide a proof-of-concept framework for developing measurement-based design principles for split-aptamer biosensors. - Source: PubMed
Adams Alexandra MPimentel Edward BLoh N DuaneGidi YasserHein Linus AEisenstein MichaelSoh H Tom - Between January 2020 and August 2023, India documented over 450 million confirmed cases of COVID-19 and nearly 0.5 million COVID-19 deaths. While reported mortality rates in India appeared lower than expected, the actual mortality may be higher due to underreporting and disparities in healthcare access. This study aimed to compare mortality before and during the COVID-19 pandemic and identify associated socio-demographic factors in rural Pune, Maharashtra, India using longitudinal population-based data from the Vadu Health and Demographic Surveillance System. - Source: PubMed
Publication date: 2026/08/30
Kand UddhaviKabudula ChodziwadziwaChoudhari BharatMohanty Tapas KumarBhujbal SandeepGondhali ArunkumarBashingwa Jean J HTippett Barr Beth ATollman StephenJuvekar SanjayKawade AnandAgarwal Dhiraj