EMP3 antibody Polyclonal Antibodies Primary antibodies
- Known as:
- EMP3 (anti-) Polyclonal Antibodies Primary antibodies
- Catalog number:
- orb101259
- Product Quantity:
- 100
- Category:
- -
- Supplier:
- Biorb
- Gene target:
- EMP3 antibody Polyclonal Antibodies Primary antibodies
Related genes to: EMP3 antibody Polyclonal Antibodies Primary antibodies
- Gene:
- EMP3 NIH gene
- Name:
- epithelial membrane protein 3
- Previous symbol:
- -
- Synonyms:
- YMP
- Chromosome:
- 19q13.33
- Locus Type:
- gene with protein product
- Date approved:
- 1997-12-05
- Date modifiied:
- 2016-10-05
Related products to: EMP3 antibody Polyclonal Antibodies Primary antibodies
Related articles to: EMP3 antibody Polyclonal Antibodies Primary antibodies
- Diabetic retinopathy (DR) is a major complication of diabetes leading to severe visual impairment. PANoptosis, a pro-inflammatory programmed cell death (PCD), has emerged as a potential pathological mechanism. This study aimed to elucidate the role of membrane protein-mediated PANoptosis in key cell populations during DR progression and to screen for coregulated genes with therapeutic potential. - Source: PubMed
Publication date: 2026/05/23
Li JingChen YicongChao YunxiangZhang YupengGan FanYou Zhipeng - Hereditary spastic paraplegia (HSP) refers to a heterogeneous group of genetic disorders with more than 90 causative genes. Clinically, HSP is classified into pure and complicated forms. Pure forms are characterized primarily by lower-limb spasticity and weakness, whereas complicated forms include additional neurological or non-neurological symptoms alongside spasticity and weakness. We aimed to characterize the clinical and genetic landscapes of HSP in an Iranian cohort. Whole-exome sequencing (WES) was performed on 103 unrelated clinically suspected HSP probands. Multiple ligation-dependent probe amplification (MLPA) was performed to validate identified copy number variants (CNVs) in two probands. - Source: PubMed
Publication date: 2026/05/12
Davarzani AtefehRavanbod MoezGhasemi AidaMohammadi MahsaRohani MohammadNafissi ShahriarJamali PaymanNajmabadi HosseinFatehi FarzadAlavi ShahryarFiroozfar ZahraZemorshidi FaribaHabibi-Kavashkohie Mohammad RezaAlavi Afagh - Blood bank identification of antibodies against high-prevalence antigens remains a challenge due to the scarcity of antigen-negative reagent red cells sourced from blood donors. The MAM antigen, encoded by EMP3, is one such antigen associated with red cell alloimmunization and hemolytic disease of the fetus and newborn. - Source: PubMed
Publication date: 2026/04/24
Gunawardena NaomiAn Hyun HyungVeliquette Randall WCarvalho EdmundDalui SambitTakasaki KaoruWafula EricFrench Deborah LPavani GiuliaChou Stella T - EMP3 is closely associated with HER2 expression and trastuzumab resistance. However, the prognostic value of EMP3 in the HER2 subtype remains poorly understood. It is necessary to clarify the relationship between EMP3 and prognosis in HER2-enriched breast cancer. - Source: PubMed
Zhu MingdaTian ChenyangNkenfag Ninine MartheWang NiannianYu Weiping - Undifferentiated sarcomas (USs), including undifferentiated pleomorphic sarcoma (UPS), are aggressive mesenchymal malignancies with limited molecular biomarkers for prognostic assessment and therapeutic stratification. Expression-based markers may provide insight into tumor aggressiveness and clinical outcomes. Here, we performed integrative transcriptomic and spatial analyses to identify differentially expressed genes (DEGs). By comparing normal tissues with sarcoma tumors and sarcoma tumors with cell lines. Intersection and clustering analyses were conducted to define shared expression programs, which revealed a subset of DEGs enriched in epithelial-mesenchymal transition (EMT)-related pathways. CosMx spatial transcriptomics was applied to xenograft tumors derived from two UPS cell lines to resolve tumor-intrinsic signatures. The National Cancer Center Cohort samples were used for validation, and immunohistochemistry confirmed the expression in thirty US tissues. Spatial transcriptomic profiling identified mesenchymal tissue-driven gene expression programs in UPS xenografts. Across bulk RNA-seq and spatial data, epithelial membrane protein 3 (EMP3) consistently emerged as highly expressed in US tissues and cell lines. EMP3 is a robust mesenchymal-associated biomarker linked to EMT, tumor progression, and clinical outcomes in USs, supporting its potential utility as a prognostic indicator and therapeutic target. - Source: PubMed
Publication date: 2026/04/06
Lee Eun-YoungCho AhyoungPark Seog YunKim June HyukKang Hyun GuyPark Jong WoongLim Jae HyangKwon JoonhaYou Hye Jin