PPP2R3A antibody Polyclonal Antibodies Primary antibodies
- Known as:
- PPP2R3A (anti-) Polyclonal Antibodies Primary antibodies
- Catalog number:
- orb100650
- Product Quantity:
- 100
- Category:
- -
- Supplier:
- Biorb
- Gene target:
- PPP2R3A antibody Polyclonal Antibodies Primary antibodies
Related genes to: PPP2R3A antibody Polyclonal Antibodies Primary antibodies
- Gene:
- PPP2R3A NIH gene
- Name:
- protein phosphatase 2 regulatory subunit B''alpha
- Previous symbol:
- PPP2R3
- Synonyms:
- PR130, PR72
- Chromosome:
- 3q22.2-q22.3
- Locus Type:
- gene with protein product
- Date approved:
- 1993-01-25
- Date modifiied:
- 2018-02-13
Related products to: PPP2R3A antibody Polyclonal Antibodies Primary antibodies
Related articles to: PPP2R3A antibody Polyclonal Antibodies Primary antibodies
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Feng TingQiu YunChen BailiHuang XuanzhiFeng RuiHe YaoZeng ZhirongChen MinhuZhang Shenghong - Necroptosis, a form of programmed inflammatory cell death, plays a crucial role in tumor development, necrosis, metastasis, and immune response. This study aimed to explore the role of necroptosis in BLCA and construct a new prognostic model to guide clinical treatment and predict individualized treatment response. - Source: PubMed
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Yao DongnuanYu WeitaoMa XuemingTian Junqiang - Clinical studies have indicated a comorbidity between sepsis and kidney diseases. Individuals with specific mutations that predispose them to kidney conditions are also at an elevated risk for developing sepsis, and vice versa. This suggests a potential shared genetic etiology that has not been fully elucidated. - Source: PubMed
Publication date: 2024/07/17
Zhang TianlongCui YingJiang SiyiJiang LuSong LijunHuang LeiLi YongYao JialiLi Min - The activity, localization, and substrate specificity of the protein phosphatase 2A (PP2A) heterotrimer are controlled by various regulatory B subunits. PR72 belongs to the B'' gene family and has been shown to be upregulated in human heart failure. However, little is known about the functions of PR72 in the myocardium. - Source: PubMed
Publication date: 2023/10/06
Herting Julius RKönig Jule HHadova KatarinaHeinick AlexanderMüller Frank UPauls PaulSeidl Matthias DSoppa CarolinaKirchhefer Uwe - Bone marrow mesenchymal stem cell (BSMC)-derived extracellular vehicles (EVs) have a pivotal therapeutic potential in hepatic fibrosis (HF). Activation of hepatic stellate cells (HSCs) is the key mechanism in HF progression. Downregulation of miR-192-5p was previously observed in activated HSCs. Nonetheless, the functions of BSMC-derived exosomal miR-192-5p in activated HSCs remain unclear. In this study, transforming growth factor (TGF)-β1 was used to activate HSC-T6 cells to mimic HF in vitro. Characterization of BMSCs and BMSC-derived EVs was performed. Cell-counting kit-8 assay, flow cytometry, and western blotting revealed that TGF-β1 increased cell viability, promoted cell cycle progression, and induced upregulation of fibrosis markers in HSC-T6 cells. Overexpression of miR-192-5p or BMSC-derived exosomal miR-192-5p suppressed TGF-β1-triggered HSC-T6 cell activation. RT-qPCR revealed that protein phosphatase 2 regulatory subunit B'' alpha (PPP2R3A) was downregulated in miR-192-5p-overexpressed HSC-T6 cells. Luciferase reporter assay was used for verifying the relation between miR-192-5p and PPP2R3A, which showed that miR-192-5p targeted PPP2R3A in activated HSC-T6 cells. Collectively, BMSC-derived exosomal miR-192-5p targets PPP2R3A and inhibits activation of HSC-T6 cells. - Source: PubMed
Publication date: 2023/05/25
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