RBP4 antibody Polyclonal Antibodies Primary antibodies
- Known as:
- RBP4 (anti-) Polyclonal Antibodies Primary antibodies
- Catalog number:
- orb100527
- Product Quantity:
- 100
- Category:
- -
- Supplier:
- Biorb
- Gene target:
- RBP4 antibody Polyclonal Antibodies Primary antibodies
Related genes to: RBP4 antibody Polyclonal Antibodies Primary antibodies
- Gene:
- POLR2D NIH gene
- Name:
- RNA polymerase II subunit D
- Previous symbol:
- -
- Synonyms:
- RBP4
- Chromosome:
- 2q14.3
- Locus Type:
- gene with protein product
- Date approved:
- 1993-12-07
- Date modifiied:
- 2016-10-05
- Gene:
- RBP4 NIH gene
- Name:
- retinol binding protein 4
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 10q23.33
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-22
- Date modifiied:
- 2015-12-04
Related products to: RBP4 antibody Polyclonal Antibodies Primary antibodies
Related articles to: RBP4 antibody Polyclonal Antibodies Primary antibodies
- Dietary retinoid bioavailability involves the interplay of the intestine (transport and metabolism) and the liver (secondary metabolism). To reproduce these processes in vitro, differentiated human intestinal Caco-2/TC7 cells were co-cultured with two hepatocyte cell lines. Murine 3A cells and the more highly differentiated human HepaRG hepatocytes were both shown to respond to β-carotene (BC) and retinol (ROH) treatment by secreting Retinol Binding Protein 4 (RBP4). In co-culture experiments, Caco-2/TC7 were differentiated on filter inserts and transferred for the time of the experiment to culture wells containing confluent 3A or differentiated HepaRG cells. Functionality of the co-cultures was assayed using as endpoints the retinol-dependent secretion of RBP4 and the retinoic acid-dependent induction of CYP26A1 in hepatocytes. BC and ROH added to intestinal Caco-2/TC7 induced a reduction in intracellular RBP4 levels in the underlying hepatocytes and its secretion into the medium. HepaRG hepatocytes were also shown to up-regulate the expression of CYP26A1 mRNA in response to retinoid treatment. This in vitro model represents a useful tool to analyze the absorption and metabolism of retinoids and could be further developed to investigate other dietary compounds and molecules of pharmacological interest. - Source: PubMed
Publication date: 2012/04/20
Rossi CarlottaGuantario BarbaraFerruzza SimonettaGuguen-Guillouzo ChristianeSambuy YulaScarino Maria LauraBellovino Diana - Lipocalin family proteins, including adipocyte fatty acid-binding protein (A-FABP), lipocalin-2 and retinol-binding protein 4 (RBP4), have recently been identified as novel adipokines associated with obesity, type 2 diabetes and the metabolic syndrome. We have evaluated the effect of exercise training on lipocalin family proteins and inflammatory markers. - Source: PubMed
Publication date: 2008/08/15
Choi K MKim T NYoo H JLee K WCho G JHwang T GBaik S HChoi D SKim S M