HTLV I&II Ab (screening)
- Known as:
- HTLV I&II Antibody (detection)
- Catalog number:
- HTLVAB.CE
- Product Quantity:
- 192 Tests n
- Category:
- -
- Supplier:
- DiaPro
- Gene target:
- HTLV & (screening)
Related genes to: HTLV I&II Ab (screening)
- Gene:
- SLC2A1 NIH gene
- Name:
- solute carrier family 2 member 1
- Previous symbol:
- GLUT1, GLUT, HTLVR, CSE
- Synonyms:
- DYT18, DYT9
- Chromosome:
- 1p34.2
- Locus Type:
- gene with protein product
- Date approved:
- 1994-11-18
- Date modifiied:
- 2019-04-23
Related products to: HTLV I&II Ab (screening)
Related articles to: HTLV I&II Ab (screening)
- 4'-Demethyl-epipodophyllotoxin (4'-DMEP) is a precursor of etoposide and has attracted much attention due to its significant antitumor activity. In order to elucidate the molecular mechanism of its inhibition of lung adenocarcinoma (LUAD), this study comprehensively used network pharmacology, machine learning, and molecular simulation technology, and verified it through cell experiments. A total of 171 drug targets and 11,439 disease targets were collected from the public database, and 131 intersection targets were obtained using the Venny tool. Then the 131 targets were visualized by PPI network. Subsequently, 38 significantly differentially expressed targets were screened and identified in the GEPIA database, from which 18 survival-related genes were further screened. GO functions related to mitotic cell cycle regulation and ERK1/ERK2 signaling, as well as KEGG pathways including gap junction and infection-related pathways, were also enriched. Four machine learning models screened five characteristic genes (SLC2A1, TOP2A, MIF, TLR4, and PLA2G1B). Molecular docking confirmed high-affinity interactions (binding energies ≤ -6.1 kcal/mol), a finding that was further validated by molecular dynamics simulation. In vitro experiments revealed that 4'-DMEP inhibited A549 cell proliferation by inducing cell cycle arrest and apoptosis, with significant changes in the expression of SLC2A1, TOP2A, and MIF. These findings not only clarify its molecular mechanism but also provide new ideas for the precise treatment of lung adenocarcinoma. - Source: PubMed
Publication date: 2026/04/03
Yao JinghuiWang ChenhaoWang ZhichaoXiang ShiSun WuChen HuiYang Chao - Hypoxia-inducible factor-1α (HIF-1α) regulates multiple pathways involved in metabolism, inflammation, and coagulation and may contribute to thrombotic complications in patients with BCR::ABL1-negative myeloproliferative neoplasms (MPN). This study investigated the expression of selected HIF-1α-regulated and thrombo-inflammatory genes (SLC2A1, F3, SELP, VEGFA, SERPINE1, PROS1, NLRP3 and THBS1) and their association with thrombotic events, JAK2 mutation status, and cytoreductive therapy. - Source: PubMed
Publication date: 2026/04/16
Morath OlgaWolfrum ThereseCrodel CarlHochhaus AndreasErnst ThomasRinke Jenny - High-dose-rate brachytherapy boost (HDR-BTb) combined with external beam radiotherapy (EBRT) improves biochemical relapse-free survival (bRFS) in localised prostate cancer (PCa) yet ∼21% of patients relapse despite dose escalation. Hypoxia and angiogenesis biomarkers have been linked to treatment outcomes through immunohistochemistry (IHC) but genomic validation at the transcriptomic level remains lacking. This study hypothesised that hypoxia- and angiogenesis-related gene expression profiles could predict clinical benefit from HDR-BTb escalation, refining patient selection. - Source: PubMed
Publication date: 2026/03/15
Lodhi TReardon MQuiles C GRojas A MChoudhury AHoskin P - Psychedelics such as psilocybin are known for their hallucinogenic properties and have also been reported to produce long-lasting therapeutic effects in depression and possibly also other psychiatric disorders. Several lines of evidence suggest that psilocybin exerts its effects through activation of 5-HT2A receptors located postsynaptically to serotonergic neurons, e.g., in the frontal cortex, parts of the limbic system, including the amygdala and hippocampus, and striatum. The present study was conducted to shed further light on psilocybin-induced changes in gene expression. - Source: PubMed
Publication date: 2026/04/10
Veysi AshkanAtanasovski DanielaArdalan MaryamMotamed NasrinEriksson Elias - Colorectal liver metastases (CRLM) are a major cause of cancer-related deaths. Glucose transporter 1 (GLUT1) is a key mediator of glycolytic metabolism in malignant and immune cells; however, the prognostic relevance of compartment-specific GLUT1 patterns in CRLM remains undefined. We hypothesized that spatial GLUT1 expression at the tumor-liver interface may reflect clinically relevant microenvironmental biology. - Source: PubMed
Publication date: 2026/04/06
Grießhammer EvaBogovic NiklasGeissler Edward KEvert KatjaGötz MarkusHackl ChristinaFichtner-Feigl StefanSchlitt Hans JBrunner Stefan M