Proteins IL-7 , Human
- Known as:
- Proteins Interleukin-7 , Human
- Catalog number:
- C086
- Product Quantity:
- 10μg
- Category:
- -
- Supplier:
- Novoprotein
- Gene target:
- Proteins IL-7 Human
Related genes to: Proteins IL-7 , Human
- Gene:
- IL7 NIH gene
- Name:
- interleukin 7
- Previous symbol:
- -
- Synonyms:
- IL-7
- Chromosome:
- 8q21.13
- Locus Type:
- gene with protein product
- Date approved:
- 1989-10-12
- Date modifiied:
- 2016-10-11
- Gene:
- IL7R NIH gene
- Name:
- interleukin 7 receptor
- Previous symbol:
- -
- Synonyms:
- CD127, IL7RA
- Chromosome:
- 5p13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1991-08-07
- Date modifiied:
- 2019-04-23
Related products to: Proteins IL-7 , Human
Related articles to: Proteins IL-7 , Human
- Autoimmune encephalitis (AE) is a major cause of acute and subacute neuropsychiatric syndromes. - Source: PubMed
Publication date: 2026/06/09
Srivastava ArpnaSingh Rajesh KumarBanerjee JyotirmoyA ElavarasiDas AnimeshRamanujam BhargaviParihar JasminePandit Awadh KishorV Y VishnuVibha DeeptiChandra SaratSrivastava M V PadmaTripathi Manjari - Immunotherapy has shown limited efficacy in metastatic castration-resistant prostate cancer (mCRPC), highlighting the need for noninvasive tools to monitor treatment-related biological changes. This case series evaluated exploratory metabolic imaging correlates using [F]-FDG PET/CT in mCRPC patients enrolled in a Cancer Immunotherapy Trials Network (CITN) trial of sipuleucel-T (sip-T) with or without recombinant interleukin-7 (IL-7). Among 54 enrolled patients (NCT01881867), three underwent serial [F]-FDG PET/CT imaging at baseline and following sip-T therapy. Imaging assessed tumor metabolic activity and potential immune-related metabolic changes, based on the premise that immune processes may influence FDG uptake. Patient 1, treated with sip-T alone, demonstrated progressive sternal metastasis with stable SUV and marked increases in metabolic tumor volume (MTV: 10.1-34.5) and total lesion glycolysis (TLG: 43.4-145.8), consistent with poor prognosis. Patient 2 showed minimal tumor avidity but transient increases in splenic SUV and SUV following sip-T, which may reflect treatment-related or immune-associated metabolic activity. Patient 3, treated with sip-T plus IL-7, demonstrated a 33% reduction in SUV, stable disease on follow-up imaging, decreased PSA levels, and metabolic changes consistent with treatment response in this individual case. These findings were observed in a single patient and are considered exploratory and hypothesis-generating only. [F]-FDG PET/CT imaging may provide exploratory insights into metabolic changes in tumors and immune-related organs in mCRPC. Metabolic changes in tumors and immune organs may provide insights into treatment-associated biological effects. Larger studies are warranted to validate these findings. - Source: PubMed
Publication date: 2026/06/05
Panikar Sandeep SurendraBansal DhruvCrandall JohnRaman HariPicus JoelIppolito Joseph EThorek Daniel L JWahl RichardPachynski Russell K - Pregnancy requires finely regulated immunological adaptation, in which interleukins play central roles in mediating maternal-fetal communication and maintaining immune equilibrium. Acute fetal distress (distress acuta) is associated with inflammatory processes that may compromise placental function and pregnancy outcomes. The present study aimed to investigate the expression patterns and distribution of selected interleukins-IL-1α, IL-2, IL-4, IL-6, IL-7, IL-8, and IL-10-in placental tissues across three gestational stages (28, 31, and 40 weeks). - Source: PubMed
Publication date: 2026/06/11
Brikune ElizabeteJunga AnnaBrikune JanaPilmane Māra - The limited efficacy of immunotherapy in hepatocellular carcinoma (HCC) is largely attributed to the formation of an immunosuppressive tumor microenvironment, in which abnormal cholesterol metabolism plays an important role. Here, we investigated the effects of signaling lymphocytic activation molecule family member 7 (SLAMF7) on the cholesterol metabolism of HCC. - Source: PubMed
Publication date: 2026/06/09
Weng JialeiWang FuXu WenxinZhao LiqianChang YushunLu HaowenXu KaiZheng HemingWang YifanCai Xiujun - Bronchodilator response (BDR) is a key clinical feature in childhood asthma, but its relation to asthma pathophysiology is not fully understood. This study examines the associations between BDR, disease control, and serum cytokines/chemokines in children with moderate-to-severe asthma (MSA). - Source: PubMed
Metwally Nariman K AHashimoto SimoneVijverberg Susanne J HNeerincx Anne HDierdorp Barbara SDekker TamaraHaarman Eric GDuitman Jan WillemGorenjak MarioToncheva Antoaneta AHarner SusanneBrandstetter SusanneWolff ChristineCorcuera-Elosegui PaulaLópez-Fernández LeyreSardón-Prado OlaiaPino-Yanes MariaPotočnik UrošKabesch MichaelKraneveld Aletta DLutter RenéTerheggen-Lagro Suzanne W JAbdel-Aziz Mahmoud IMaitland-van der Zee Anke H