PTX3 Polyclonal Antibody
- Known as:
- PTX3 Polyclonal Antibody
- Catalog number:
- A-0489-050
- Product Quantity:
- 50
- Category:
- -
- Supplier:
- EpigenTek
- Gene target:
- PTX3 Polyclonal Antibody
Related genes to: PTX3 Polyclonal Antibody
- Gene:
- PTX3 NIH gene
- Name:
- pentraxin 3
- Previous symbol:
- TNFAIP5
- Synonyms:
- TSG-14
- Chromosome:
- 3q25.32
- Locus Type:
- gene with protein product
- Date approved:
- 1993-11-08
- Date modifiied:
- 2016-10-05
Related products to: PTX3 Polyclonal Antibody
Related articles to: PTX3 Polyclonal Antibody
- Rheumatoid arthritis (RA) is characterized by persistent synovitis. Conventional inflammatory markers like C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) inadequately reflect synovial inflammation, particularly under interleukin-6 pathway inhibition. Pentraxin 3 (PTX3), an extrahepatic acute-phase protein produced in inflamed tissues, may better reflect local inflammation and angiogenesis in RA joints. - Source: PubMed
Publication date: 2026/06/08
Wang LiuqingChen XinYang MingfengHua Li - Long Covid (LC) is an inflammatory condition, affecting multiple organs, including kidneys. This study aims to identify a signature of inflammatory biomarkers that can predict, describe, and monitor kidney function decline in LC patients. - Source: PubMed
Publication date: 2026/06/05
Borriello MargheritaRanieri RobertaCoppola AnnapaolaLombari PatriziaNevola RiccardoMarrone AldoSignoriello GiuseppeAdinolfi Luigi ElioCoppola NicolaIngrosso DianaLongo Flavia MariaDi Maro ChristianAlfieri Carlo MariaIngrosso DiegoSimeoni MariadelinaPerna Alessandra - Arrhythmogenic cardiomyopathy (ACM) is an inherited disease that is characterized by lethal ventricular arrhythmias stemming from myocyte dysfunction. ACM is associated with considerable subepicardial fibrosis and inflammation with right ventricle predominance. Most cases of gene-positive ACM are caused by a desmosome protein mutation, with plakophilin-2 () mutations being the most common. We hypothesized that -deficiency in epicardium-derived cells (EPDCs) contributes to fibro-inflammatory signaling and ACM pathogenesis. - Source: PubMed
Publication date: 2026/06/05
Han Daniel DBrooks Alan CBaker Cameron DDirkx Ronald AMickelsen Deanne MFisler BenjaminPhadke KavyaAshton John MDelmar MarioSmall Eric M - Dengue virus (DENV) infection can manifest as dengue fever (DF) or dengue hemorrhagic fever (DHF), although DHF often becomes clinically apparent around defervescence. How complement components and other immune responses evolve over the course of illness from the febrile to recovery phase remains incompletely defined. This study characterized circulating complement activation and immune mediators in DF and DHF using paired febrile and early-recovery samples. - Source: PubMed
Publication date: 2026/06/04
Saptarini IkaMasyeni SriHarahap Alida RoswitaGiantini AstutiNugroho PringgodigdoHandito AgusHendarwan HarimatSusilo AdityoHaryanto SotianingsihFitriani DesiSasmono R TedjoNelwan Erni Juwita - Silica nanoparticles (SiNPs) are considered as one of the excellent alternative negative electrode materials for optimizing the storage performance of lithium-ion batteries. Therefore, with the global transition to new energy, their production may rapidly increase, but there is still a lack of relevant research on occupational exposure risks, especially respiratory toxicity mechanisms and biomarkers, associated with lithium-ion battery-related SiNPs. This study investigated the mechanism of toxic effects and possible biomarkers of SiNPs on human bronchial epithelial cells (BEAS-2B) using integrative transcriptomic, proteomic, and metabolomic approaches. SiNPs used in this study were selected as the most relevant type of negative electrode material for lithium-ion batteries, and their physical and chemical properties were characterized in detail. It was found that SiNPs induced significant concentration- and time-dependent cytotoxicity on BEAS-2B cells. SiNPs could alter the multiomics phenotype of cells after treatment with 50 μg/mL for 24 h. Multiomic joint analysis found that SiNPs may have induced cytotoxicity through toxic pathways, including oxidative stress, inflammation, and fibrosis, screening possible biomarkers such as PTX3, SESN2, STC2, IL-6, CLDN1, and COL14A1. This study revealed the possible mechanisms and biomarkers of respiratory toxicity of lithium-ion battery-related SiNPs and also suggested that integrative omic analyses could be a useful approach for evaluating the toxicity of novel nanoparticles. - Source: PubMed
Publication date: 2026/06/03
Zhou XinyanShi JiaqiMa YingZhang YiLi XiaojinPeng BinshuaiJia GuangChen Zhangjian