mTOR Polyclonal Antibody
- Known as:
- Mammalian target on rapamycin Polyclonal Antibody
- Catalog number:
- A-0422-100
- Product Quantity:
- 100
- Category:
- -
- Supplier:
- EpigenTek
- Gene target:
- mTOR Polyclonal Antibody
Related genes to: mTOR Polyclonal Antibody
- Gene:
- MTOR NIH gene
- Name:
- mechanistic target of rapamycin kinase
- Previous symbol:
- FRAP, FRAP2, FRAP1
- Synonyms:
- RAFT1, RAPT1, FLJ44809
- Chromosome:
- 1p36.22
- Locus Type:
- gene with protein product
- Date approved:
- 1995-07-18
- Date modifiied:
- 2019-04-23
Related products to: mTOR Polyclonal Antibody
Related articles to: mTOR Polyclonal Antibody
- Laterally spreading tumors (LST) are flat colorectal neoplasms with an accelerated risk of malignant transformation and interval colorectal cancer. Despite their clinical importance, the molecular and microbial mechanisms underlying LST's aggressive biology remain poorly understood. Thus, we aimed to characterize the transcriptomic and microbial landscape of LST in comparison with paired protruding lesions and the adjacent normal colonic tissue. - Source: PubMed
Publication date: 2026/08/21
Lutsiv TymofiyThompson Henry JFiehn OliverGareau Melanie GBorowsky Alexander DChen Brian HHussan Hisham - Tuberous sclerosis complex (TSC) is a rare autosomal dominant neurodevelopmental disorder caused by loss-of-function mutations in or , resulting in chronic hyperactivation of the mechanistic target of rapamycin (mTOR) pathway. TSC patients experience a wide spectrum of cognitive, behavioral, and psychiatric features collectively termed Tuberous Sclerosis Complex Associated Neuropsychiatric Disorders (TAND). Moreover, these patients develop a clinical trajectory in adulthood with clinical and neuropathological features overlapping those of Alzheimer's disease (AD). Prior neuropathological studies have shown accumulation of AD-type mixed 3R/4R tau isoforms in adults with TSC that is amyloid-independent. - Source: PubMed
Publication date: 2026/09/11
Baumel JocelynLutz MichaelDing CynthiaCapal JamieRitter DavidKrueger DarcySalter AliceWerner KlausLiu Andy J - Pulmonary hypertension (PH) is a progressive and fatal disease characterized by pulmonary vascular remodeling, inflammation, and immune dysregulation. Myeloid-derived suppressor cells (MDSCs) and macrophages contribute to PAH pathobiology; however, the molecular regulators of their pathological activation remain poorly defined. The triggering receptor expressed on myeloid cells 2 (TREM2) is an immunomodulatory receptor that shapes myeloid cell metabolism, survival, and immunosuppressive function, yet its role in PAH has not been investigated. - Source: PubMed
Publication date: 2026/09/24
Oliveira Aline Cda Silva FilipeZhang YutaoAlves Matthew DPham Ann THarris CharlotteKhanfar SultanAbdelnor RafaelAlvarez-Castanon JimenaPhillips CarolineHall Mia TFu ChunhuaVirk Shiza TRay Katherine EChen Lide Kloet AnnetteKrause EricBryant Andrew J - Gestational diabetes mellitus (GDM) is a common metabolic disorder, posing serious health risks to both mother and fetus. This study aims to explore the placental endocrine mechanisms involved in GDM. - Source: PubMed
Deng LijunYang MoWang XinGong NingZhang NingYang QingGu Chengmin - Glioblastoma (GBM), IDH-wildtype WHO Grade IV, is the most aggressive primary brain tumour. Although temozolomide (TMZ) remains standard-of-care, ~50% develop resistance driven by cytoprotective autophagy. GORASP2, an autophagy regulator linked to hyperactivated mTOR signaling in GBM, remains largely unexplored. This study characterized the molecular significance of GORASP2 across independent Western and Eastern cohorts using an integrative multi-database approach.. - Source: PubMed
Iqbal YusraHanif Farina