AChE antibody
- Known as:
- AChE (anti-)
- Catalog number:
- 10-1855
- Product Quantity:
- 200 ul
- Category:
- -
- Supplier:
- Fitzgerald
- Gene target:
- AChE antibody
Related genes to: AChE antibody
- Gene:
- ACHE NIH gene
- Name:
- acetylcholinesterase (Cartwright blood group)
- Previous symbol:
- YT
- Synonyms:
- -
- Chromosome:
- 7q22.1
- Locus Type:
- gene with protein product
- Date approved:
- 1989-06-02
- Date modifiied:
- 2019-04-23
Related products to: AChE antibody
Related articles to: AChE antibody
- - Source: PubMed
Carrasco-Labra AlonsoPolk DeborahUrquhart Olivia - Atlantoaxial rotatory fixation (AARF) in children usually responds to conservative treatment, including rest and cervical collar immobilization. However, some patients experience persistent or recurrent deformity and require prolonged immobilization or more intensive treatment. Long-term outcomes of prolonged AARF managed without halo vest immobilization have rarely been reported. We report the case of an eight-year-old boy who presented with acute neck pain and torticollis without an identifiable trigger. Initial treatment with a cervical collar at a local clinic failed to improve his symptoms, and he was referred to our hospital two weeks after symptom onset. He was admitted and treated with 1.5-kg Glisson traction. Although his symptoms and cervical alignment initially improved, neck pain and torticollis repeatedly recurred after attempts to discontinue traction and transition to a cervical collar. Traction was therefore resumed several times. On hospital day 35, immobilization was changed to a cervicothoracic orthosis to provide better rotational control. Progressive sitting, standing, and gait training were subsequently introduced, and the patient was discharged home on hospital day 78. The cervicothoracic orthosis was changed to a cervical collar on day 238, and the collar was discontinued on day 315. Follow-up CT performed at six months showed improvement in cervical alignment and facet morphology. At the five-year follow-up, the patient remained asymptomatic and had a full cervical range of motion. CT demonstrated slight residual facet deformity without progression, bony ankylosis, or degenerative changes. This case demonstrates a favorable long-term clinical outcome after prolonged AARF managed with traction and external orthoses without general anesthesia, manipulation, or halo vest immobilization. In carefully selected pediatric patients in whom corrected alignment can be achieved and maintained, prolonged nonoperative management may be a treatment option. However, the contributions of natural growth and the natural history of AARF cannot be excluded, and further studies are required to determine the appropriate indications and efficacy of this approach. - Source: PubMed
Publication date: 2026/08/11
Ito RyotaOshita Yusuke - - Source: PubMed
Publication date: 2026/08/25
de Lima Wesley Antônio LopesGouveia Mariana CarvalhoBonadio Renata Colombo - Metal hypersensitivity in spinal surgery is an immune-mediated reaction to metal ions released from implants like pedicle screws and rods, presenting a notable clinical challenge. Common allergens such as nickel, cobalt, and chromium can trigger delayed-type IV hypersensitivity, resulting in pain, inflammation, implant loosening, and the need for revision surgery. Risk factors include prior metal exposure through jewelry or implants, as well as comorbidities like diabetes and behaviors like smoking. Diagnosis is complex, as symptoms often resemble infection or mechanical failure, necessitating the use of tools like patch testing, lymphocyte transformation testing, and histopathological analysis. Management strategies focus on preoperative risk assessment, selection of hypoallergenic materials like PEEK or titanium, and revision surgery when hypersensitivity is confirmed. Multidisciplinary collaboration involving spine surgeons, allergists, and dermatologists is crucial for accurate diagnosis, effective treatment, and improved patient outcomes, emphasizing the importance of tailored implant choices and vigilant postoperative care. - Source: PubMed
Publication date: 2026/08/21
Adebusoye Favour TopeKarkhanis SimranShet VallabhMane Rohan SAroori ParinitaLucke-Wold BrandonChan Julie LHoh DanielDecker MatthewFields Daryl PinionRoth Steven GKrafft Paul R - Modern orthoplastic surgery has expanded the possibilities of limb preservation after severe extremity trauma through advances in microsurgical reconstruction, skeletal stabilization, vascular repair, and multidisciplinary trauma care. However, increasing reconstructive capability has also emphasized the distinction between anatomical limb preservation and meaningful long-term recovery. Despite technically successful salvage, some patients experience chronic pain, repeated procedures, prolonged rehabilitation, impaired mobility, psychological distress, and socioeconomic decline. This editorial re-examines conventional salvage paradigms and argues that reconstructive success should not be defined solely by flap survival, fracture union, infection control, vascular patency, or limb retention. Traditional scoring systems, including the Mangled Extremity Severity Score, Limb Salvage Index, and Nerve Injury, Ischemia, Soft-Tissue Injury, Skeletal Injury, Shock, and Age of Patient Score, remain limited in predicting long-term functional and patient-centered outcomes. Evidence from the Lower Extremity Assessment Project and the Military Extremity Trauma Amputation/Limb Salvage Study highlights the complex relationship between limb preservation, functional recovery, quality of life, and return to meaningful participation after severe lower extremity trauma. This editorial proposes a broader patient-centered framework for salvage decision-making that incorporates biological viability, functional utility, rehabilitative feasibility, and contextual life circumstances. Ultimately, successful limb salvage should be defined not only by technical reconstruction but by whether recovery restores sustainable function, independence, and meaningful participation in life. - Source: PubMed
Publication date: 2026/08/05
Loon Muhammad MuazZarif Shabir