Human S100A10 Protein
- Known as:
- Human S100A10 Protein
- Catalog number:
- S10-H5127
- Product Quantity:
- 1mg
- Category:
- -
- Supplier:
- acrobyosystems
- Gene target:
- Human S100A10 Protein
Related genes to: Human S100A10 Protein
- Gene:
- S100A10 NIH gene
- Name:
- S100 calcium binding protein A10
- Previous symbol:
- ANX2LG, CAL1L
- Synonyms:
- P11, 42C, CLP11
- Chromosome:
- 1q21.3
- Locus Type:
- gene with protein product
- Date approved:
- 1992-09-10
- Date modifiied:
- 2018-05-02
Related products to: Human S100A10 Protein
Related articles to: Human S100A10 Protein
- Following subarachnoid hemorrhage (SAH), long-lasting inflammation triggered by activated glial cells has adverse effects on neurological recovery. As an α2 adrenoceptor agonist commonly utilized for sedative purposes, dexmedetomidine (DEX) has demonstrated the ability to confer neuroprotective effects across diverse physiological or pathological conditions. This study was designed to determine whether DEX protects against SAH by altering astrocytic reactivity. - Source: PubMed
Publication date: 2026/04/24
Yin JiaxiangXu QiaominLu KuanWu JinchaoCai Weiwei - Subarachnoid hemorrhage (SAH) is associated with high mortality and poor outcomes, which are closely related to white matter injury (WMI). (-)-Epigallocatechin-3-gallate (EGCG) exerts neuroprotective effects by inhibiting oxidative stress-related ferroptosis in astrocytes and improving neurological function. However, the role and mechanism of EGCG in regulating reactive astrocytes (RAs) to alleviate WMI after SAH remain unclear. - Source: PubMed
Publication date: 2026/04/28
Lang DongcenZheng YanningZhang JingLi ZhengNiu MengyuWang JianWang XueHuang LiyongXue JiangyuLi LiChen Ying - The emergence of variant strains of (ARV) has caused substantial economic losses in the poultry industry worldwide, but the molecular features of goose-origin strains and viral transmission among different avian species remain poorly understood. Here, we describe a goose-origin avian orthoreovirus strain, SD0407, associated with growth retardation and joint swelling. Complete genome analysis identified ten double-stranded RNA segments. Sequence comparison indicated that SD0407 is closely related to previously reported duck-origin reovirus strains. Phylogenetic and recombination analyses showed that most segments clustered with duck-origin strains, indicating close genetic relatedness among waterfowl-origin orthoreoviruses. Sequence and structural analysis of the σC attachment protein revealed ten unique amino acid substitutions, including D250 within the DE-loop region involved in receptor-binding. Molecular docking suggested that σC interacts with the conserved AnxA2-S100A10 heterotetrameric receptor complex, providing a possible structural basis for receptor compatibility across avian species. Although SD0407 replicated efficiently in goose embryo fibroblasts, it did not induce expression of type I, II or III interferons. Transcriptome profiling revealed weak activation of innate immune signaling and downregulation of metabolic and cytoskeletal genes, consistent with effective suppression of antiviral responses. These findings demonstrate that SD0407 combines structural variability with immune evasion to enhance host adaptability and underscore the importance of sustained ARV surveillance in waterfowl populations. - Source: PubMed
Publication date: 2026/04/08
Liu YijiaLi YongXie YingxuanWang MeiYin BoxuanLi ChangyanZhang LilinHua DepingLiu JunweiZheng XintianHuang Jinhai - To observe the effect of acupuncture on astrocyte activation following cerebral ischemia-reperfusion injury (CIRI) the p38 mitogen-activated protein kinase (p38 MAPK)/mitogen- and stress-activated protein kinase 1 (MSK1) signaling pathway. - Source: PubMed
Zifeng ZhuangChoying W OHongling ChenHailiang XieCanghuan ZhaoDi ZhangPeng Qing - The incidence of thyroid cancer has been increasing in recent years, with papillary thyroid carcinoma (PTC) accounting for the majority of cases. Accumulating studies have demonstrated that S100A10 acts as an oncogene in the progression of various malignancies. However, the function and specific mechanisms of S100A10 in thyroid cancer remain poorly defined. - Source: PubMed
Publication date: 2026/04/16
Song WenbinLiu ZhaoyiShi CangchangWang GuixinHe LongChen ZhaohuiLi YingxiYu YueJiang RuoyuWang XiaoningZhao KeChen ZiyiTian YaoQi FengWang YizengHe Xianghui