KIR2DL1 protein, Native & Recombinant Proteins
- Known as:
- KIR2DL1 protein, Native & Recombinant Proteins
- Catalog number:
- 30R-1030
- Product Quantity:
- 100 ug
- Category:
- -
- Supplier:
- Fitzgerald
- Gene target:
- KIR2DL1 protein Native & Recombinant Proteins
Related genes to: KIR2DL1 protein, Native & Recombinant Proteins
- Gene:
- KIR2DL1 NIH gene
- Name:
- killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
- Previous symbol:
- -
- Synonyms:
- cl-42, nkat1, 47.11, p58.1, CD158A
- Chromosome:
- 19q13.42
- Locus Type:
- gene with protein product
- Date approved:
- 1997-11-14
- Date modifiied:
- 2016-11-09
Related products to: KIR2DL1 protein, Native & Recombinant Proteins
Related articles to: KIR2DL1 protein, Native & Recombinant Proteins
- Reproductive failures, including recurrent implantation failures (RIF), recurrent pregnancy losses (RPL), and adverse pregnancy outcomes (APO), are increasingly linked to immunological factors at the maternalfetal interface. Killer immunoglobulin-like receptors (KIRs) on natural killer (NK) cells play a key role in regulating maternal immune responses to trophoblast HLA-C antigens. - Source: PubMed
Kovarova TerezaBitoova MartinaLuxova StepankaKoudova MonikaKoucky MichalCerna Karin - The killer-cell immunoglobulin-like receptors (KIR) are a family of activating and inhibitory Class I human leukocyte antigen (HLA-I) binding receptors expressed on natural killer (NK) cells and subsets of T cells. The KIR detect HLA-I molecules in a peptide-dependent manner, with some KIR displaying exquisite peptide specificity. Studying peptide recognition by KIR often uses TAP-deficient cell lines expressing single HLA-I alleles, which are heterogenous and time consuming to generate. Here, we established an alternative approach using peptide-exchange technologies hitherto developed for studying T cell recognition of HLA-I. - Source: PubMed
Publication date: 2026/05/25
Murali Tanusya MLi BeiningHoos EmeryCollinson LucyLong Eric ODushek OmerElliott TimSim Malcolm J W - Immune dysregulation and cognitive deficits are increasingly recognized in adolescent major depressive disorder (MDD), yet their interrelationship remains unclear. This study aimed to investigate peripheral immune-inflammatory alterations and natural killer (NK) cell phenotypes, and explore their association with cognitive function in adolescent MDD. - Source: PubMed
Publication date: 2026/05/16
Wang JiahuiHou LingzhiLi CaiLiu YitongXu YanHe YangYang LeiWang LiLiu QidongCheng JunZhang YanyanMa YunmiaoXu HaiweiLi Hong - The Novel KIR3DL1*0010123, KIR3DL1*0010124, KIR2DL1*0010108, KIR2DL1*0010109 alleles were identified in healthy individuals from the Indian Population. - Source: PubMed
Sharma GauravAgarwal DishaKhadwal AlkaDas ReenaMalhotra Pankaj - The killer-cell immunoglobulin-like receptor () gene cluster exhibits complicated diversity in haplotype content, copy-number variation (CNV), and allelic polymorphism. To date, 2,286 distinct alleles have been released in the IPD-KIR Database. However, little is known about the impact of high-resolution-level allelic polymorphisms on leukemia. Our previous study showed that the genotype carrying more inhibitory genes conferred differential protection against leukemia in the Chinese Southern Han population. Herein, we hypothesized the impact of alleles in the haplotype and cognate human leukocyte antigen (HLA) ligand on leukemia. - Source: PubMed
Publication date: 2026/02/05
Deng ZhihuiZhen JianxinLi YunanLiang ShuangZhang ManruCai SiqiJiang RenhuiYang ZhichaoYu QiongWang JinyongLiu Jie