Mouse Anti Human Interleukin-16 IL16
- Known as:
- Mouse Anti Human Interleukin-16 IL16
- Catalog number:
- ant-370
- Product Quantity:
- 5
- Category:
- -
- Supplier:
- Prospecbio
- Gene target:
- Mouse Anti Human Interleukin-16 IL16
Related genes to: Mouse Anti Human Interleukin-16 IL16
- Gene:
- IL16 NIH gene
- Name:
- interleukin 16
- Previous symbol:
- -
- Synonyms:
- LCF, IL-16, prIL-16, HsT19289, FLJ42735, FLJ16806
- Chromosome:
- 15q25.1
- Locus Type:
- gene with protein product
- Date approved:
- 1997-07-25
- Date modifiied:
- 2016-10-05
Related products to: Mouse Anti Human Interleukin-16 IL16
Related articles to: Mouse Anti Human Interleukin-16 IL16
- High salt (HS) intake is a known cardiovascular risk factor, yet the mechanisms linking salt intake to endothelial dysfunction remain unclear. We investigated whether HS induces vascular senescence and dysfunction, and whether targeting senescent cells could prevent these effects. - Source: PubMed
Publication date: 2026/04/16
Nascimento André FLuvizotto Renata A MCosta Rafael MPimenta Gustavo FBruder ArianeBruder-Nascimento Thiago - Accurate radiation biodosimetry is urgently needed for medical management after large-scale radiation exposure. Partial-body irradiation with 5% bone marrow sparing (PBI/BM5) provides a realistic radiation model. The current study specifically focused on the high-dose lethality window (12-16 Gy), where survival transitioned from 100% to 0%, representing a clinically distinct and underserved scenario requiring dedicated biodosimetry tools. We defined the survival profile of male C57BL/6 mice after PBI/BM5 and found that doses of 13.5-14.0 Gy were nonlethal within 12 days, whereas 15.0-15.5 Gy caused 100% mortality within 12 days, with a calculated LD of 14.68 Gy. A separate cohort of 14.0 Gy showed 100% survival up to 90 days post-radiation. To develop serum cytokine-based biodosimetry in high-dose radiation exposure, mice were exposed to 12.0-16.0 Gy PBI/BM5, and serum was collected on days 1, 3, and 7. A multiplex cytokine assay was used to quantify 70 total cytokines/chemokines. After the exclusion of 4 targets outside detection limits, 66 markers were utilized for downstream analysis. PCA, clustering and heatmaps, and LASSO classification revealed that cytokine signatures can classify radiation groups/status/doses. A 4-cytokine panel (IL-7, GDF-15, IL-16 and FLT3L) could distinguish naïve vs. irradiated mice on all study days. A 24-cytokine signature panel distinguished radiation survivors vs. non-survivors, and another 34-cytokine panel separated radiation doses (12-16 Gy); the prediction was better on day 7 compared to earlier time points. This exploratory study was specifically designed to define the systemic inflammatory response in a high-dose window where survival transitions from 100% to 0% (the 'lethality threshold') in a clinically relevant partial-body irradiation model. These findings show that serum cytokines have strong potential for high-dose triage, survival prediction, and dose discrimination within the near-lethal exposure range in a clinically relevant PBI/BM5 model. Extension to lower dose ranges is an important direction for future work. - Source: PubMed
Publication date: 2026/04/01
Cui WanchangHull LisaRothstein AsherWang LiLin BinZhai MinWeaver AliaXiao Mang - Coccidiosis is a protozoan disease that causes serious economic losses annually worldwide. This study evaluated thyme oil and quercetin as natural anticoccidial treatments in broiler chickens experimentally infected with . In total, 450 one-day-old Hubbard broiler chicks were allocated into 10 groups. On the eighth day of age, five groups remained uninfected: a negative control group (-ve) and early-treated and late-treated groups treated with thyme oil or quercetin. The other five groups were infected with : a positive control group (+ve) and early-treated and late-treated groups treated with thyme oil or quercetin. The clinical signs, parasitologic findings, oxidative stress biomarkers, and the relative expressions of interleukins 2, 6, and 16 were evaluated on the sixth, 11th, and 16th days postinfection (dpi). The infection induced bloody diarrhea, weight loss, and high lesion scores in +ve controls, while the infected, thymol-treated (ITE) group yielded the best clinical recovery, lowest lesion scores, and highest weight gain among infected groups. Oocyst shedding peaked at 8 dpi but was significantly reduced in early-treated groups, particularly ITE. Oxidative stress biomarkers and interleukin relative expressions were significantly altered, with early treatment improving antioxidant status and modulating immune responses. In conclusion, the results recommend the early administration of either thyme oil or quercetin to improve the productivity, oxidative stress, and birds' immune response against infection. - Source: PubMed
Mohamed Rania AAli Haytham ASalem Gamal AHussein Ashraf - Here we investigate the status of the adiponectin-PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. - Source: PubMed
Publication date: 2026/04/13
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Publication date: 2026/04/07
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