Multiplex ELISA Kits Cytokine (IL1α, IL1β, IL6, IL8, GMCSF, INF-γ, MCAF and TNFα), human, Sensitivity Ref to insert, Assay Range Ref to insert
- Known as:
- Multiplex Enzyme-linked immunosorbent assay test Kits Cytokine (IL1α, IL1β, IL6, IL8, GMCSF, INF-γ, MCAF TNFα), H. sapiens, Sensitivity Ref insert, Assay Range Ref insert
- Catalog number:
- EM10001
- Product Quantity:
- 96 wells
- Category:
- -
- Supplier:
- Anogen
- Gene target:
- Multiplex ELISA Kits Cytokine (IL1α IL1β IL6 IL8 GMCSF INF-γ MCAF and TNFα) human Sensitivity Ref insert Assay Range
Related genes to: Multiplex ELISA Kits Cytokine (IL1α, IL1β, IL6, IL8, GMCSF, INF-γ, MCAF and TNFα), human, Sensitivity Ref to insert, Assay Range Ref to insert
- Gene:
- ARID3A NIH gene
- Name:
- AT-rich interaction domain 3A
- Previous symbol:
- DRIL1
- Synonyms:
- BRIGHT
- Chromosome:
- 19p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1997-08-22
- Date modifiied:
- 2015-11-17
- Gene:
- BCL2L13 NIH gene
- Name:
- BCL2 like 13
- Previous symbol:
- -
- Synonyms:
- MIL1, BCL-RAMBO
- Chromosome:
- 22q11.21
- Locus Type:
- gene with protein product
- Date approved:
- 2002-09-20
- Date modifiied:
- 2016-10-05
- Gene:
- BPIFB2 NIH gene
- Name:
- BPI fold containing family B member 2
- Previous symbol:
- C20orf184, BPIL1
- Synonyms:
- dJ726C3.2, LPLUNC2
- Chromosome:
- 20q11.21
- Locus Type:
- gene with protein product
- Date approved:
- 2001-11-14
- Date modifiied:
- 2015-12-07
- Gene:
- BTF3P11 NIH gene
- Name:
- basic transcription factor 3 pseudogene 11
- Previous symbol:
- BTF3L1
- Synonyms:
- HUMBTFB, TNFRSF11B, OPG, OCIF
- Chromosome:
- 13q22.3
- Locus Type:
- pseudogene
- Date approved:
- 1997-12-12
- Date modifiied:
- 2016-10-05
- Gene:
- C1QL1 NIH gene
- Name:
- complement C1q like 1
- Previous symbol:
- -
- Synonyms:
- CRF, C1QRF, C1QTNF14, CTRP14
- Chromosome:
- 17q21.31
- Locus Type:
- gene with protein product
- Date approved:
- 2004-05-06
- Date modifiied:
- 2018-07-16
Related products to: Multiplex ELISA Kits Cytokine (IL1α, IL1β, IL6, IL8, GMCSF, INF-γ, MCAF and TNFα), human, Sensitivity Ref to insert, Assay Range Ref to insert
[Tyr63] PTH (63_84), human
Human ELC ELISA KIT 96 TEST
OxiSelect Hydroxyl Radical Antioxidant Capacity (HORAC) Activity Assay, Trial Size
OxiSelect In Vitro ROS/RNS Assay Kit (Green Fluorescence), Trial Size
OxiSelect Methylglyoxal (MG) Competitive ELISA Kit
OxiSelect Methylglyoxal (MG) Competitive ELISA Kit
OxiSelect TBARS Assay Kit (MDA Quantitation), Trial Size
OxiSelect Total Antioxidant Capacity (TAC) Assay Kit, Trial Size
OxiSelect™ In Vitro ROS RNS Assay Kit (Green Fluorescence), Trial Size"Fish_tail" soft stirring disc for 0.4, 1, 3 and 7l reactor"Fish_tail" soft stirring disc for 0.4, 1, 3 and 7l reactor, modified geometry and material for softer stirring"Recombinant Human Carboxypeptidase E_CPE""Recombinant Human Carboxypeptidase E_CPE""Recombinant Human Carboxypeptidase E_CPE""Recombinant Human Carboxypeptidase E_CPE" Related articles to: Multiplex ELISA Kits Cytokine (IL1α, IL1β, IL6, IL8, GMCSF, INF-γ, MCAF and TNFα), human, Sensitivity Ref to insert, Assay Range Ref to insert
- Autoimmune myocarditis frequently progresses to inflammatory cardiomyopathy through dysregulated immune-stromal interactions. This study employs single-nuclei RNA-sequencing (snRNA-seq) to profile 46,233 cardiac nuclei from the experimental autoimmune myocarditis (EAM) mouse model at four timepoints: day 0 (healthy), day 14 (inflammation), day 21 (acute inflammation), and day 40 (late cardiac remodelling). Single-nuclei RNA profiling identified 18 transcriptionally distinct cell populations. Global cell-cell communication analysis revealed a dramatic peak of intercellular signalling at day 14 (5907 interactions), with fibroblast subpopulations and macrophages as dominant hubs, followed by partial resolution at day 21 (2264 interactions) and renewed remodelling at day 40 (4862 interactions). Subclustering of the macrophage compartment identified five subpopulations: Mac-TLF, Mac-MHCII, Mac-rMHCII, Mac-ResL, and Classical Monocytes. Tissue-resident macrophages (Mac-TLF, CCR2-) dominated at healthy state (~55%) but were rapidly depleted at day 14, coinciding with a dramatic influx of recruited CCR2 macrophages (Mac-rMHCII), which expanded to over 70% of the compartment and maintained dominance through day 40. At inflammation (day 14), the expanded Mac-rMHCII subpopulation displayed a strongly pro-inflammatory signature (, , , ), and the overall macrophage compartment was enriched for cytokine response, Fc-gamma receptor, and Notch signalling pathways, while downregulating homeostatic and mitochondrial metabolic programmes, potentially contributing to impaired efferocytosis and cardiomyocyte dysfunction. Macrophage-centred communication networks expanded markedly at day 14 (1047 interactions), with resting fibroblasts (FB-R) as the primary signalling partner, driving pro-inflammatory stromal activation marked by upregulation of , , and . Intra-macrophage subcluster communication also intensified at this timepoint (447 interactions). These findings delineate the temporal and functional heterogeneity of cardiac macrophages during EAM progression and identify key immune-stromal interactions driving pathological cardiac remodelling. The coexistence of pro-inflammatory and transitional reparative macrophage subsets highlights the limitations of broad immunosuppression and supports precision strategies targeting CCR2-mediated recruitment, the SPP1 signalling axis, and macrophage-fibroblast crosstalk as therapeutic avenues in myocarditis and its progression. - Source: PubMed
Publication date: 2026/06/19
Stefanska MonikaKot MartaKoterba DamianZeyland Joanna - It is documented that antigens can induce immune responses able to regulate complex diseases. Conversely, the dysregulated inflammatory response in leprosy increases morbidity and leads to reactional episodes, impairing the disease pathogenesis. The goal of this study was to evaluate the potential of the (Sm29) antigen in regulating the immune response in leprosy through a transcriptome study across clinical reactional forms: reversal reaction (RR), and erythema nodosum leprosum (ENL), and without reaction (WR). - Source: PubMed
Publication date: 2026/06/01
Karoline Silva Joycede Farias Lucas NevesLago TainãCardoso Luciana Dos SantosKhouri RicardoMachado Paulo RobertoCastellucci Léa Cristina - To explore the effect and mechanism of the Yiqi Huoxue Granule in improving the survival of mesenchymal stem cells (MSCs) induced by hypoxia and promoting angiogenesis in damaged tissues. - Source: PubMed
Publication date: 2026/01/21
Shi WeiliWang ShuhuiLiu ShanshanLei ZhenYan PeishuoWang XinzhouLu ChaoqunQin NanLu Pengfei - Palmitic acid (PA) is the most common dietary saturated fatty acid, and is abundant in palm and cottonseed oil, butter, and cheese, whereas oleic acid (OA) is a monounsaturated omega-9 fatty acid found in olive oil. The differences in the cytotoxic and pro-inflammatory effects of PA and OA across endothelial cells (ECs) isolated from different vascular beds have not been investigated in detail. Here, we incubated primary human aortic valve (HAVEC), saphenous vein (HSaVEC), internal thoracic artery (HITAEC), and microvascular (HMVEC) ECs with albumin-bound PA or OA for 24 h and found that PA induced a considerable cytotoxic response, accompanied by an elevated expression of the genes encoding cell adhesion molecules (, , , and ) and pro-inflammatory cytokines (, , , , , , , , , , , , , , , , , and ), followed by an increased release of interleukin-6 and interleukin-8. HAVEC and HSaVEC were more susceptible to PA, whereas OA had mild-to-moderate cytotoxic effects on HAVEC and HMVEC but did not induce generalized EC activation. Compared with other EC types, HITAEC was the most resistant to PA and OA treatment. Collectively, these results indicate considerable heterogeneity across the ECs of distinct origin in response to PA. - Source: PubMed
Publication date: 2025/12/17
Shishkova DariaMarkova VictoriaYurieva YuliaFrolov AlexeyLazebnaya AnastasiaSinitsky MaximSinitskaya AnnaMatveeva VeraTorgunakova EvgeniaStepanov AlexanderMalashicheva AnnaKhapchaev AskerPodkuychenko NikitaVorotnikov AlexanderShirinsky VladimirKutikhin Anton - The objective of this study was to assess inflammatory and immune responses in patients with asthma and healthy controls exposed to a polluted and a nonpolluted environment over a short period. - Source: PubMed
Publication date: 2025/12/03
Soler-Segovia DavidRomero-Mesones ChristianEspejo DavidPilia FlorenciaOjanguren IñigoMartinez-Rivera CarlosMuñoz XavierCruz Mª Jesus