TOB1 Control Peptide antibody _CP
- Known as:
- TOB1 Control Peptide (anti-) _CP
- Catalog number:
- 'AP18225CP-N
- Product Quantity:
- 0.1 mg
- Category:
- -
- Supplier:
- ACR
- Gene target:
- TOB1 Control Peptide antibody _CP
Related genes to: TOB1 Control Peptide antibody _CP
- Gene:
- TOB1 NIH gene
- Name:
- transducer of ERBB2, 1
- Previous symbol:
- TROB1
- Synonyms:
- TOB, TROB, APRO5
- Chromosome:
- 17q21.33
- Locus Type:
- gene with protein product
- Date approved:
- 2000-06-01
- Date modifiied:
- 2016-07-04
Related products to: TOB1 Control Peptide antibody _CP
Related articles to: TOB1 Control Peptide antibody _CP
- Benign prostatic hyperplasia (BPH), the most prevalent male chronic disease, features typical lower urinary tract symptoms (LUTS) that compromise male health. Angiogenesis, the formation of new vascular networks from pre-existing vessels, is typically related to cancer development and inflammatory microenvironments. Identifying and diagnosing angiogenesis-related genes implicated in BPH is of critical importance for the health management of the BPH population. Therefore, this study aims to identify and validate angiogenesis-related genes associated with BPH to provide potential biomarkers for its diagnosis and treatment. - Source: PubMed
Publication date: 2026/08/27
Cui MengfanKostadinovic KristinaMeng QiBai TingGu YunjiaLiu Shimin - Osteoarthritis (OA) and type 2 diabetes mellitus (T2DM) frequently coexist and share inflammatory and metabolic disturbances, but the immune-epigenetic features that may overlap between these conditions remain incompletely defined. Enhancer RNAs (eRNAs) are increasingly recognized as regulators of enhancer activity and transcriptional programs, whereas eRNA-associated signatures shared between OA-related and T2DM-related datasets remain largely unexplored. - Source: PubMed
Publication date: 2026/07/17
Huang DanniWu JunyingChen JinhuaWu QianWang Shengnan - To be clinically useful in goal-directed fluid therapy, a fluid challenge (FC) must achieve a large enough blood volume change (ΔBV) to materially change ventricular preload and stroke volume (ΔSV). The same % change in BV for all the subsequent FCs must also be achieved. We explored under what circumstances these prerequisites can be met by referring to data from a clinical trial where 111 patients underwent three successive intravenous FCs using crystalloid (Ringer´s lactate) or colloid (hydroxyethyl starch), involving a total of 9 mL/kg of fluid, just after induction of general anaesthesia. - Source: PubMed
Publication date: 2026/05/22
O'Brien TerryHahn Robert G - Thymoquinone (TQ), the principal bioactive component of Nigella sativa, has attracted considerable attention for its potential anticancer properties. However, its antiproliferative effects and the underlying molecular mechanisms across different cancer cell types remain incompletely understood. - Source: PubMed
Publication date: 2026/05/22
Yüce HandeBerberoğlu YaseminAşkın Özek DilanÜnüvar Songül - Elevated sodium concentrations are commonly observed in tumors and sites of inflammation. Previous studies have shown that high salt levels modulate the phenotype and function of CD4 and CD8 T cells, regulatory T cells, and macrophages. In this study, we performed transcriptomic studies that revealed profound alterations in the neutrophil transcriptome upon high salt exposure, with changes that significantly exceeded those triggered by conventional agonists. By integrating transcriptomic data with functional assays, our findings suggest that high salt-induced neutrophil activation involves mitochondrial ROS production, which subsequently activates p38 MAPK and engages FOS-, Bruton's tyrosine kinase (BTK)-, and cyclooxygenase 2 (COX2)-dependent pathways. Remarkably, the plasticity of the neutrophil transcriptome in response to high salt was further evidenced by the upregulation of genes typically associated with other cell types, including semenogelin 1 (), intercellular adhesion molecule-4 (), tripartite motif69 (), amphiregulin (), oncostatin (), and transducer of ERBB2-1 (), suggesting a broader role for neutrophils in different biological processes beyond their participation in innate immunity. - Source: PubMed
Publication date: 2026/01/21
Mazzitelli IgnacioBleichmar LucíaRivelli FedericoFeijoo IngridAdamczyk AlanCabrerizo GonzaloErra Díaz FernandoGeffner Jorge