EGR1 EMSA Probe Set
- Known as:
- EGR1 EMSA Probe Set
- Catalog number:
- AY1303P
- Product Quantity:
- 25 rxn
- Category:
- -
- Supplier:
- Panomics
- Gene target:
- EGR1 EMSA Probe Set
Related genes to: EGR1 EMSA Probe Set
- Gene:
- EGR1 NIH gene
- Name:
- early growth response 1
- Previous symbol:
- -
- Synonyms:
- TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225
- Chromosome:
- 5q31.2
- Locus Type:
- gene with protein product
- Date approved:
- 1988-08-11
- Date modifiied:
- 2016-10-05
Related products to: EGR1 EMSA Probe Set
(+) Control probe (DNA), biotinylated(+) Control probe (RNA), biotinylated(-) Control probe (DNA), biotinylated(-) Control probe (RNA), biotinylated0.2 mm, 30 cm Spacer Set
0.2 mm, 30 cm Spacer Set0.35 mm, 30 cm Spacer Set
0.35 mm, 30 cm Spacer Set0.5 mm, 30 cm Spacer Set
0.5 mm, 30 cm Spacer Set0.75 mm Dual Gel Cast Set
0.75 mm Dual Gel Cast Set0.75 mm Plate Set, RM
0.75 mm Plate Set, RM
0.75 mm Plate Set, RM
Related articles to: EGR1 EMSA Probe Set
- The dismal prognosis of breast cancer brain metastasis (BCBM) is attributed to a maladapted tumor microenvironment. This study was aimed at deciphering the role of novel intercellular communicators, tumor-derived migrasomes, in driving BCBM progression, with a focus on their ability to co-opt brain-resident microglia. - Source: PubMed
Publication date: 2026/09/08
Wang SongXian XinmiaoGu GuohaoGuo JianranAn MengLi DongbaoWang QianHuang XuefangChen ShenZhang WeiFu Bo - Mouse neuroblastoma cells (N2a) are spontaneously derived from mice and possess the characteristics of neural stem cells. The proliferation, differentiation, and protrusion growth of N2a cells in vitro are consistent with those in vivo. Flavonoids isolated from the aerial parts of Scutellaria barbata (SBFs) can improve learning and memory deficits and protect against neuronal injury in many in vivo AD-- like models. N2a cells exposed to Aβ25-35 for Alzheimer's disease-related toxicity were subsequently used to observe the ameliorative effects of SBFs, and the effective mechanism through which SBFs promote the phosphorylation of CREB was further studied by using BI-D1870, an indirect inhibitor, and Rolipram, an activator of CREB phosphorylation. - Source: PubMed
Publication date: 2026/08/28
Yu XiaominYi YanLiu XinyangZhao ChunyingLi CaixiaShang YazhenHe KeZhai Yujian - To explore the protective effects of selenium nanoparticles (SeNPs) against renal, hepatic, and reproductive toxicity induced by aflatoxin, male Sprague-Dawley rats (n = 36), 3 months old and weighing 162-233 g (198.17 ± 2.64 g), were equally divided into control, SeNPs, aflatoxin, and SeNPs-aflatoxin groups. Blood and tissue samples from the liver, kidneys, and testicles were collected. Luteinizing hormone (LH), testosterone, estradiol (E2), interleukin-β (IL-β), transforming growth factor-β (Tgf-β), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), total antioxidants (TAC), nitric oxide (NO), AST, ALT, and creatinine were measured. DNA fragmentation and the expression of activity-regulated cytoskeleton-associated protein (Arc), Early growth response factor 1 (Egr1), and JunB Proto-Oncogene (JunB) were determined in the liver. SeNPs and SeNPs-aflatoxin increased testosterone (P < 0.001) and estradiol (P = 0.004) but lowered TGF-β (P = 0.013) compared with the aflatoxin group. Aflatoxin decreased SOD (P < 0.047) and CAT (P < 0.0001) activities and increased NO concentrations (P = 0.004). SeNPs, aflatoxin, and SeNPs-aflatoxin decreased AST (P < 0.01) and ALT (P < 0.0001) but increased creatinine (P < 0.001). Aflatoxin and SeNPs-aflatoxin increased DNA fragmentation% and hepatic Arc, Egr1, and JunB expression (P < 0.0001), whereas SeNPs decreased them. Aflatoxin caused severe degenerative alterations in the testis, liver, and kidneys, including vacuolization, necrosis, and structural disorganization. SeNPs mitigated the toxic effects of aflatoxin by improving tissue organization and minimizing cellular damage. Significant histological improvements were noted, although full restoration was not achieved. In conclusion, SeNPs could protect to some extent against the hepatic and testicular toxic effects of aflatoxin in male rats. Renal toxicity could not be ameliorated to normality due to the nephrotoxic effects of both SeNPs and aflatoxin. - Source: PubMed
Publication date: 2026/09/07
Soliman Mona M HAly Mohamed SShafey Heba IAboelmaaty Amal MMahrous Karima F - Rheumatoid arthritis (RA) and metabolic dysfunction-associated steatotic liver disease (MASLD) frequently co-occur, but their shared molecular and immunometabolic features remain incompletely defined. We integrated population-level epidemiology, hospital-based clinical phenotyping, cross-disease transcriptomic analyses, and patient-level experimental data to systematically characterise RA-MASLD comorbidity. - Source: PubMed
Publication date: 2026/09/02
Pang LijunLi YunfeiCheng LiliHuang Chuanbing - Resistance to anti-TNFα therapy (e.g., infliximab) in ulcerative colitis (UC) remains a significant clinical challenge, with the underlying cellular and spatial mechanisms poorly understood. - Source: PubMed
Publication date: 2026/08/20
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