GATA2 EMSA Probe Set
- Known as:
- GATA2 EMSA Probe Set
- Catalog number:
- AY1095P
- Product Quantity:
- 25 rxn
- Category:
- -
- Supplier:
- Panomics
- Gene target:
- GATA2 EMSA Probe Set
Related genes to: GATA2 EMSA Probe Set
- Gene:
- GATA2 NIH gene
- Name:
- GATA binding protein 2
- Previous symbol:
- -
- Synonyms:
- NFE1B
- Chromosome:
- 3q21.3
- Locus Type:
- gene with protein product
- Date approved:
- 1992-11-03
- Date modifiied:
- 2019-04-23
Related products to: GATA2 EMSA Probe Set
(+) Control probe (DNA), biotinylated(+) Control probe (RNA), biotinylated(-) Control probe (DNA), biotinylated(-) Control probe (RNA), biotinylated0.2 mm, 30 cm Spacer Set
0.2 mm, 30 cm Spacer Set0.35 mm, 30 cm Spacer Set
0.35 mm, 30 cm Spacer Set0.5 mm, 30 cm Spacer Set
0.5 mm, 30 cm Spacer Set0.75 mm Dual Gel Cast Set
0.75 mm Dual Gel Cast Set0.75 mm Plate Set, RM
0.75 mm Plate Set, RM
0.75 mm Plate Set, RM
Related articles to: GATA2 EMSA Probe Set
- Germline GATA2 deficiency predisposes to bone marrow failure, myeloid neoplasia, and immune dysregulation. The syndrome is often complicated by infection with intracellular pathogens and viruses, autoimmunity, and inflammation. Hemophagocytic lymphohistiocytosis (HLH) is a rare occurrence that can present further management challenges. Here, we describe a young adult with GATA2 deficiency presenting with pneumonia, COVID-19, and HLH with underlying -mutated myelodysplasia that responded successfully to allogeneic hematopoietic stem cell transplantation. - Source: PubMed
Publication date: 2026/05/12
Wilson HarryBorges NunoCollin MatthewWright Callum - Nontuberculous mycobacteria (NTM) skin infections pose significant diagnostic challenges in clinical practice, due to nonspecific clinical/histopathological features and limitations of conventional pathogenic detection methods. Metagenomic next-generation sequencing (mNGS) offers a promising approach but requires further evaluation. A prospective pilot study at Peking Union Medical College Hospital enrolled 20 patients with cutaneous NTM infection, confirmed by positive skin culture or mNGS. All patients underwent thorough clinical assessment, skin biopsy for histopathology and culture, and mNGS testing of skin tissue. Treatment was based on identified species and disease extent. Treatment outcomes were tracked. Among 20 patients (median age 45.5 years), fingers were the most common site affected ( = 10), followed by forearms ( = 7), hands ( = 4), and face ( = 4). was the predominant pathogen ( = 12), associated with fish bone puncture, followed by ( = 4). mNGS demonstrated a substantially higher positivity rate than culture (95% [19/20] vs. 30% [6/20]) and delivered results faster. Histopathology revealed granulomatous inflammation in all cases. Nineteen patients presented with non-disseminated disease; one immunocompromised patient (GATA2 deficiency) had disseminated infection. Treatment success was achieved in 17 patients (85%) with tailored antibiotic regimens. Adverse drug effects occurred in seven patients. In this pilot study of cutaneous NTM infections, mNGS enabled more rapid diagnosis relative to conventional culture. Clinical presentation and exposure history correlate with specific NTM species. Integrating mNGS with clinical assessment significantly improves diagnosis and management. - Source: PubMed
Publication date: 2026/05/03
Liu Jia-WeiMa XiaoQian Yue-TongWang Jing-WenZhu Chen-YuMa Dong-Lai - Long-term trophectoderm (TE) cell culture provides a powerful model to investigate placenta-specific factors to better understand mechanisms relevant to pregnancy establishment and placental development. However, current TE culture systems rely on costly commercial media and extracellular matrix (ECM) components, which limit their scalability and accessibility. This study evaluated cost-effective alternatives to established conditions by testing modified DMEM/F-12 and a biphasic TE culture system as substitutes for commercial Advanced DMEM/F-12 and for continuous TE culture, and by assessing 0.1% gelatine as an ECM alternative to collagen IV. Trophectoderm outgrowths cultured on collagen IV or gelatine did not differ in attachment timing () or in expression of placental and differentiation markers (), (), and (). Similarly, blastocysts cultured in commercial Advanced DMEM/F-12 or base DMEM/F-12 exhibited no differences in attachment day (), TE growth area from days 10-20 ( > 0.05), or expression of ( = 0.35) and ( = 0.08), although differed between treatments (). Embryos cultured in continuous TE attached later () than those cultured in TE media, but no differences were observed in TE growth area or expression of , , or (). Collectively, these results indicate that affordable media formulations and gelatine-coated cultureware support TE attachment, proliferation, and differentiation. This cost-effective culture framework enables broader application of TE models and supports extended studies of trophoblast function, placental signalling, and early conceptus development. - Source: PubMed
Publication date: 2026/05/12
Moreno Ethel SofiaCastro BrizaOrtega M Sofia - - Source: PubMed
Publication date: 2026/04/24
Francés Jesús FernándezRamo Alejandro VázquezRodríguez Guillermo Calero - Tumor-infiltrating clonal hematopoiesis (TI-CH) indicates the infiltration of somatically mutated hematopoietic cells into the tumor microenvironment. While clonal hematopoiesis is a known prognostic factor in hematologic malignant neoplasms, the clinical relevance of TI-CH in solid tumors remains poorly understood. - Source: PubMed
Publication date: 2026/05/07
Yun DabinChen ChengQin NaWang ZhaomingSong Nan