dUTP, 100 mM
- Known as:
- dUTP, 100 mM
- Catalog number:
- DU100
- Product Quantity:
- 1 ml
- Category:
- -
- Supplier:
- NanoHelix
- Gene target:
- dUTP 100
Ask about this productRelated genes to: dUTP, 100 mM
- Gene:
- DUT NIH gene
- Name:
- deoxyuridine triphosphatase
- Previous symbol:
- -
- Synonyms:
- dUTPase
- Chromosome:
- 15q21.1
- Locus Type:
- gene with protein product
- Date approved:
- 1995-09-28
- Date modifiied:
- 2015-08-25
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- Porous structures are extensively utilized in bone tissue engineering for their lightweight nature, high strength-to-weight ratio, and superior energy absorption capacity. However, achieving optimal scaffold performance through precise dimension control remains a significant design challenge. This study systematically investigates the effect of unit-cell size on the mechanical and fluid transport properties of porous bone structures, aiming to provide guidance for scaffold design. Various porous structures with controlled unit cell sizes were fabricated via Selective Laser Melting (SLM) and evaluated under compressive loading. A complementary finite element (FE) model was developed to simulate mechanical responses and extract equivalent elastic modulus and compressive strength, while computational fluid dynamics (CFD) simulations were conducted on 4 × 4 × 4 arrays to calculate permeability. Results demonstrate that the Gyroid unit cell exhibited the most uniform stress distribution among the three studied architectures (Cube, Octa, Gyroid), and reducing unit cell size effectively mitigated stress concentrations to enhance structural stability. At a constant porosity, the compressive strength of uniform porous structures decreased with increasing unit-cell size, whereas the elastic modulus showed relatively low sensitivity to size variation. Meanwhile, permeability increased markedly with increasing unit-cell size. This study confirms that unit cell size profoundly impacts both the mechanical integrity and permeability of porous bone structures: smaller unit cells are recommended for applications prioritizing high compressive strength, whereas larger unit cells are more favorable for enhanced fluid transport. - Source: PubMed
Publication date: 2026/07/31
Lyu YongtaoCao HongruiJing PeiqiLan YunfeiBosiakov SergeiElgazzar HaythamLi GuangyuLiu Yadong - SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) have been included in the latest WHO classification of tumors. This study examined the cytomorphology, management, molecular features and prognosis of malignancies harboring SMARCA4 alterations. - Source: PubMed
Publication date: 2026/08/04
Nezami Behtash GShi QiuyingLin Xiaoqi - - Source: PubMed
Publication date: 2026/08/05
Nkosi NhlanhlaNhubu TrustMthombeni Nomcebo Happiness - Photoinduced electron transfer (PeT) represents a fundamental mechanism in the design of fluorescent probes and molecular switches, typically modulated by tuning the electronic donating or withdrawing capacity of substituents. This widely adopted strategy implicitly assumes that substituent electronic effects directly translate into effective electronic coupling. Through density functional theory (DFT) and time-dependent DFT (TD-DFT) investigations, we demonstrate that this assumption is insufficient for 1,8-naphthalimide (NI) derivatives. Our results reveal that the occurrence of PeT is not governed by intrinsic electron-donating or -withdrawing ability, but rather by a simple geometric criterion: the coplanarity between the substituent and the NI core. Coplanarity activates π-conjugation between the substituent and the fluorophore, which redistributes π-electron density and attenuates the electron-accepting capacity of the NI unit, thereby suppressing PeT. In contrast, non-coplanar substituents block π-conjugation and facilitate PeT regardless of their intrinsic electronic properties. Notably, we clarify that the experimentally observed pH-dependent fluorescence enhancement originates from deprotonated anionic species rather than neutral forms. Overall, the research calls for a reassessment of conventional PeT-based molecular design strategies and provides a simple, predictive framework for the rational development of PeT-controlled luminescent materials and fluorescent probes. - Source: PubMed
Wang YuxiLi WenzhiMeng LingwenSu YanZhou Panwang - Manganese dioxide (MnO₂)-based catalysts have emerged as promising candidates for the complete oxidation of volatile organic compounds (VOCs). However, insufficient oxygen mobility and the limited availability of reactive oxygen species restrict their low-temperature catalytic performance. Herein, Ni-doped ε-MnO₂ nanosheet catalysts were synthesized via a redox-precipitation route under two distinct synthesis redox environments by tuning the KMnO₄/Mn ratio. The redox-controlled synthesis generates distinct surface chemistries, leading to different catalytic behaviors toward aromatic and oxygenated VOCs. Comprehensive structural, spectroscopic, and redox characterizations reveal that the catalyst synthesized under Mn-rich conditions possesses oxygen-vacancy-rich surfaces together with enhanced oxygen mobility and MnONi redox interactions, which correlate with superior low-temperature oxidation of toluene. In contrast, the catalyst prepared under KMnO₄-rich conditions exhibits more pronounced carbonate-modified surface chemistry, which is associated with enhanced ethyl acetate oxidation. The optimized catalysts achieve T₉₀ values of 238 °C for toluene and 198 °C for ethyl acetate oxidation. Catalytic tests under an inert atmosphere further support the direct participation of catalyst oxygen species, consistent with a Mars-van Krevelen-type oxidation mechanism. Moreover, the catalyst synthesized under Mn-rich conditions maintains nearly complete ethyl acetate conversion for 48 h at 220 °C. These results demonstrate that controlling the synthesis redox environment provides an effective strategy to tailor surface chemistry and oxygen activation in Mn-based catalysts, offering new insights into the rational design of efficient catalysts for VOC oxidation. - Source: PubMed
Publication date: 2026/07/21
Phan Nga Hang ThiNguyen Thi Tuyet NgocNguyen Phuc Hoang DuyDoan HuanTran Vinh VanLe Quyet VanNguyen Chinh-ChienDao My UyenNguyen-Dinh Minh-TuanNam Pham Cam