Antibodies Zona radiata proteins Monoclonal mouse anti-salmon zona radiata protein Purified PO-1 MN-2B4
- Known as:
- Antibodies Zona radiata proteins Monoclonal mouse (anti-) to-salmon zona radiata protein Purified PO-1 MN-2B4
- Catalog number:
- Z03402101-500
- Product Quantity:
- 500 μl
- Category:
- -
- Supplier:
- Biosense
- Gene target:
- Antibodies Zona radiata proteins Monoclonal mouse anti-salmon zona protein Purified PO-1 MN-2B4
Related genes to: Antibodies Zona radiata proteins Monoclonal mouse anti-salmon zona radiata protein Purified PO-1 MN-2B4
- Gene:
- CDCA7 NIH gene
- Name:
- cell division cycle associated 7
- Previous symbol:
- -
- Synonyms:
- FLJ14736, JPO1
- Chromosome:
- 2q31.1
- Locus Type:
- gene with protein product
- Date approved:
- 2002-04-03
- Date modifiied:
- 2014-11-19
- Gene:
- FNIP2 NIH gene
- Name:
- folliculin interacting protein 2
- Previous symbol:
- -
- Synonyms:
- KIAA1450, FNIPL, MAPO1
- Chromosome:
- 4q32.1
- Locus Type:
- gene with protein product
- Date approved:
- 2008-03-06
- Date modifiied:
- 2015-09-11
- Gene:
- GFER NIH gene
- Name:
- growth factor, augmenter of liver regeneration
- Previous symbol:
- -
- Synonyms:
- HSS, ERV1, ALR, HERV1, HPO1, HPO2
- Chromosome:
- 16p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1997-03-19
- Date modifiied:
- 2018-02-22
- Gene:
- KPNB1 NIH gene
- Name:
- karyopherin subunit beta 1
- Previous symbol:
- -
- Synonyms:
- NTF97, IPOB, MGC2155, MGC2156, MGC2157, IMB1, Impnb, IPO1
- Chromosome:
- 17q21.32
- Locus Type:
- gene with protein product
- Date approved:
- 1997-04-21
- Date modifiied:
- 2016-02-01
- Gene:
- ODF3 NIH gene
- Name:
- outer dense fiber of sperm tails 3
- Previous symbol:
- -
- Synonyms:
- SHIPPO1, hSHIPPO, CT135
- Chromosome:
- 11p15.5
- Locus Type:
- gene with protein product
- Date approved:
- 2002-12-09
- Date modifiied:
- 2014-11-18
Related products to: Antibodies Zona radiata proteins Monoclonal mouse anti-salmon zona radiata protein Purified PO-1 MN-2B4
Related articles to: Antibodies Zona radiata proteins Monoclonal mouse anti-salmon zona radiata protein Purified PO-1 MN-2B4
- Most inhibitors of lipid peroxidation (LPO) and associated ferroptosis are small molecules that trap LPO-propagating radicals. Among the handful of other inhibitors are select fatty acids: monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids substituted with deuterium atoms at their reactive bis-allylic positions (D-PUFAs), which render them significantly less reactive to LPO-propagating radicals. To probe whether the simple replacement of oxidizable PUFAs with non-oxidizable FAs is a general strategy for ferroptosis suppression, we prepared derivatives of representative PUFAs-linoleic acid (LA) and arachidonic acid (AA)-with cyclopropane rings in place of their unsaturations (CP-PUFAs). Cyclopropanation was predicted to boost the strength of the neighboring C-H bonds by ∼20 kcal/mol and increase the barrier to reaction with peroxyl radicals by ∼104-fold while preserving their cis geometry. CP-PUFAs suppressed ferroptosis induced by erastin2 in HT-1080 cells and RSL3 in HEK-293 cells, similarly to D-PUFAs and MUFAs. Palmitate, a representative endogenous saturated FA, did not suppress ferroptosis. Whereas d6-AA was more effective than d2-LA, the opposite was true of the CP-PUFAs, with CP4-AA possessing only modest activity while CP2-LA was comparable to the D-PUFAs. Lipidomics provides evidence for more extensive lipid remodeling upon treatment with CP2-LA relative to CP4-AA, with PUFAs being enriched in triacylglycerols at the expense of the diacylglycerols used for phospholipid synthesis. Overall, these results suggest that replacement of oxidizable PUFAs with non-oxidizable FAs is a general strategy to suppress ferroptosis-provided that the non-oxidizable FA can be utilized by the biosynthetic machinery and is not lipotoxic at concentrations necessary for protection. - Source: PubMed
Publication date: 2026/09/29
Mallais MelodieSzylo KrystinaMagtanong LeslieShchepinov Mikhail SDixon Scott JPratt Derek A - Type 2 diabetes mellitus (T2D) is the leading cause of end stage renal disease. Screening for chronic kidney disease is recommended for early diagnosis and intervention. This requires assessment of renal function by computing for estimated glomerular filtration rate (eGFR) and urine albumin-creatine ratio. Several formulas have been proposed for computation of eGFR. The European Renal Function Consortium (EKFC) equation, obtained by combining the full age spectrum (FAS) and Chronic Kidney Disease - Epidemiology Collaboration 2021 (CKD-EPI) equations, has been proposed as a more universal formula for eGFR. It has the advantage of eliminating correction for ethnicity and covers a wide age range. The aim of this study is to compare the EKFC and CKD-EPI 2021 equations to assess eGFR among Algerian population with T2D. - Source: PubMed
Publication date: 2026/08/29
Sedoud ZohraBaghdali Feriel YasmineHind ArzourMassinissa OuzriatSabrine DeghimaFarid HaddoumKamel Djenouhat - Insights into how permanent microporosity influences ion transport in polymer electrolytes could facilitate the design of next-generation single-ion conducting (SIC) materials. Intrinsically microporous polymers and conventional polymers are typically regarded as fundamentally distinct electrolyte platforms; direct comparisons between compositionally similar examples are lacking. Here, we introduce a strategy for the synthesis of fluorinated aryl sulfonimide-based polymers of intrinsic microporosity (FAS-PIMs) together with flexible polysulfonimide analogs of similar composition that lack permanent microporosity. Although these polymers possess fundamentally different dry-state architectures, incorporation of a common pore-filling transport medium, succinonitrile (SN), drives the two systems toward remarkably similar nanostructures with similar bulk conductivities (>10-10 S/cm at 40°C-80°C), thermomechanical properties (G' within 1-10 MPa over the temperature range of 25°C-120°C), and reprocessability. Molecular dynamics simulations and experiments suggest these unusual combinations of properties arise through different conduction mechanisms within the materials, and that sulfonimide anions are particularly advantageous for conduction in microporous matrices relative to strongly binding anions. Overall, this work introduces the first sulfonimide-based PIM, establishes a comparison between permanently microporous and transiently porous single-ion conducting polymers, and demonstrates that these two traditionally distinct electrolyte architectures can converge toward similar, useful bulk properties after incorporation of a pore-filling transport medium. - Source: PubMed
Publication date: 2026/09/26
Herzog-Arbeitman AbrahamLeon PabloSchreib Benedikt SJun KyuJungRuza JurgisPerales Vanesa MunozShao-Horn YangGomez-Bombarelli RafaelJohnson Jeremiah A - The fish head contains a large number of bioactive lipids for preparing functional foods. In this study, we analyzed the fatty acid components and molecular species of tilapia head phospholipids (TH-PL), and investigated the preventive effect of them on metabolic syndrome (MS). - Source: PubMed
Publication date: 2026/09/20
Gao XiaYu HuiYi XiangzhouGao ShuxinShen Xuanri - Obesity is a metabolic disorder characterized by excessive lipid accumulation, disrupted fatty acid homeostasis, and gut microbiota dysbiosis. essential oil (ZBO) is a natural plant volatile oil with diverse bioactivities, but its anti-obesity effects and potential associations remain unclear. : HFD-induced obese (DIO) mice were evaluated to determine the effects of ZBO. Physiological parameters, glucose tolerance, and serum biochemical markers were assessed. Potential correlates were explored using a multi-omics approach, including integrated serum untargeted metabolomics, 16S rRNA gene sequencing, and RT-qPCR analysis of key genes involved in lipid metabolism in the liver and white adipose tissue. : ZBO significantly mitigated HFD-induced body weight gain, visceral adiposity, hepatic steatosis, dyslipidemia, and glucose intolerance. Metabolomics indicated that ZBO administration was associated with alterations in the serum metabolic landscape, particularly in pathways related to fatty acid metabolism and AMPK/PPAR-α signaling. Consistently, ZBO treatment was associated with upregulated mRNA expression of lipid-oxidizing genes (AMPK, PPAR-α, CPT1) and downregulated lipogenic genes (SREBP-1c, ACC, FAS, SCD1, LPL). 16S rRNA sequencing suggested that ZBO was associated with increased gut microbial diversity, decreased the Firmicutes/Bacteroidota ratio, and enriched beneficial taxa (e.g., Ligilactobacillus, Alistipes) while suppressing pro-inflammatory genera. Correlation analysis established robust associations between ZBO-modulated microbes and key fatty acid metabolites, particularly acylcarnitines and AMPK/PPAR-α-related intermediates. : Collectively, these multi-omics data suggest that ZBO administration is associated with remodeling of the gut microbiota and correlated changes in fatty acid metabolic pathways. These findings provide preliminary preclinical evidence supporting further investigation of ZBO in the context of dietary strategies for alleviating HFD-induced obesity. - Source: PubMed
Publication date: 2026/09/09
Sun LuchuanyangZhang ShiqiHu HongjuanXu BingbingQian ShanHuang YukunYang XiaoLiang YanChen Xianggui