Anti-Mouse CD48 PE 200 ug
- Known as:
- Antibody toMouse CD48 PE 200 ug
- Catalog number:
- 12-0481-83
- Category:
- -
- Supplier:
- eBioscience
- Gene target:
- Anti-Mouse CD48 200
Related genes to: Anti-Mouse CD48 PE 200 ug
- Gene:
- CD48 NIH gene
- Name:
- CD48 molecule
- Previous symbol:
- BCM1
- Synonyms:
- BLAST, mCD48, hCD48, SLAMF2
- Chromosome:
- 1q23.3
- Locus Type:
- gene with protein product
- Date approved:
- 1986-01-01
- Date modifiied:
- 2016-10-05
Related products to: Anti-Mouse CD48 PE 200 ug
Related articles to: Anti-Mouse CD48 PE 200 ug
- Periodontitis is a chronic inflammatory disease characterized by progressive destruction of periodontal supporting tissues, yet the molecular mechanisms underlying its pathogenesis remain incompletely defined. This study aimed to identify key genes associated with periodontitis through an integrative bioinformatics strategy combined with experimental validation. - Source: PubMed
Publication date: 2026/07/02
Gu YueBu MingyangSun JingyuanLiu JuanYu LixianYuan XuriXing CongcongHan KaixuanLiu LiangShen XiaoDanYang YakunLiu Qing - Flow cytometry (FC) incorporating the T-cell receptor constant beta chain-1 (TRBC1) antibody has rapidly gained traction as the preferred method for T-cell clonality assessment. The widespread use of this assay has identified a high prevalence of T-cell clones of uncertain significance (T-CUS) that are detected in the absence of demonstrable malignancy. We conducted a retrospective evaluation of T-CUS clones identified at our institution following the introduction of a TRBC1 antibody based FC assay in 2020. Bona fide T-CUS was identified in 92 samples from 55 patients and comprised 60 distinct T-cell clones, the majority of which were CD8+ and showed immunophenotypic overlap with T-cell large granular lymphocyte leukaemia (T-LGLL). CD4+, CD4+8+ and CD4-8- clones were also captured and described in this cohort. Expression of the NK marker CD16 was uncommon (16.7%), highlighting this as a potentially useful marker for distinguishing T-CUS from T-LGLL. In the follow-up cohort, 92% of 29 tracked clones reduced in size or stayed the same over a median follow-up of 19.6 months and no cases progressed to overt T-cell malignancy. This study demonstrates serial assessment of T-CUS clones and provides the basis for further prospective studies. - Source: PubMed
Publication date: 2026/05/14
Potezny TessaNguyen Phillip CChan Kah-LokBaldwin KylieJuneja SurenderCame NeilNguyen VuongWesterman David A - Assessing the stage of maturation is critical for the classification of T-cell neoplasms and is helpful in minimal/measurable residual disease (MRD) testing for T-lymphoblastic leukemia (T-ALL). This study analyzes the utility of CD48 in characterizing T-cell neoplasms at diagnosis and posttherapy. - Source: PubMed
Torabi AlirezaFromm Jonathan RDorer RussellDing YannaGlynn EmilyEdlefsen Kerstin LShameli AfshinWu DavidCherian Sindhu - Acute lung injury (ALI) is a significant post-operative complication of liver transplant (LT), with mounting evidence suggesting a role for the gut-lung axis. However, the mechanistic link between gut microbiota dysbiosis and ALI pathogenesis in LT recipients remains poorly understood. This hybrid translational investigation integrates transcriptomic profiling (bulk and single-cell RNA-seq), immune infiltration analysis, fecal microbiota composition (16S rRNA), and predictive functional profiling in ALI vs. non-ALI (NALI) LT patients. Machine learning algorithms (LASSO, SVM-RFE, Random Forest) were used to identify key gene biomarkers. Microbiota-host gene correlations and canonical correspondence analysis (CCA) were performed to evaluate multi-omic relationships. ALI patients exhibited reduced gut microbial diversity and increased abundance of Enterococcus and Escherichia-Shigella, alongside a depletion of beneficial taxa (Faecalibacterium, Bacteroides). CXCL3, CD48, and IRAK3 were identified as robust ALI biomarkers (Area Under the Curve >0.83), validated in both serum and Bronchoalveolar Lavage Fluid. These genes correlated positively with pro-inflammatory microbes and immune cell infiltration. Functional prediction revealed enrichment in lipopolysaccharide biosynthesis, Toll-like receptor signaling, and bacterial chemotaxis. CCA confirmed that microbiota variation significantly explained host transcriptomic variance. Our study uncovers a functional gut-lung immunological axis in post-LT ALI. Gut dysbiosis modulates immune gene expression and lung inflammation, suggesting that the microbiome serves as a potential source of diagnostic biomarkers and therapeutic targets in transplant-associated lung injury. - Source: PubMed
Publication date: 2026/06/08
Mehboob Abdul AhadFatima RemshaKanwal SaadiaAli MuhammadKarim MonaFatima Sampana - Obesity-driven metabolic disorders involve pathological remodeling of white adipose tissue (WAT), wherein fibroblasts coordinate fibrosis and inflammation. This study aimed to characterize fibroblast transcriptional heterogeneity, identify fibrosis-inflammation mediators, and discover diagnostic and therapeutic targets. - Source: PubMed
Publication date: 2026/06/04
Li YunmengNasrin MahbubaHuo Rui