Anti-Human CD1a PE 100 tests
- Known as:
- Antibody toHuman CD1a PE 100 tests
- Catalog number:
- 12-0019-42
- Category:
- -
- Supplier:
- eBioscience
- Gene target:
- Anti-Human CD1a 100 tests
Related genes to: Anti-Human CD1a PE 100 tests
- Gene:
- CD1A NIH gene
- Name:
- CD1a molecule
- Previous symbol:
- CD1
- Synonyms:
- -
- Chromosome:
- 1q23.1
- Locus Type:
- gene with protein product
- Date approved:
- 1988-05-11
- Date modifiied:
- 2017-07-07
Related products to: Anti-Human CD1a PE 100 tests
Related articles to: Anti-Human CD1a PE 100 tests
- Leishmania-HIV coinfection compromises the cutaneous immune response through mechanisms that remain poorly understood. This exploratory study compared the in situ immune microenvironment of skin lesions between coinfected and non-coinfected patients with American tegumentary leishmaniasis (ATL). - Source: PubMed
Publication date: 2026/06/30
Xavier Marília BrasilFontes Lucas Dos SantosMotizuki Airton KenjiAlves Leonardo Ramalho MendonçaRodrigues Gabriela FernandesAlcântara Larissa Dos SantosIshikawa Edna Aoba YassuiBrito Elza Baía deGomes Cláudia Maria de CastroCorbett Carlos Eduardo Pereira - Adult-onset xanthogranuloma (AOXG) is a rare, benign form of non-Langerhans cell histiocytosis. Ocular manifestations commonly involve the orbit, uveal tract, or adnexal tissues; however, concurrent bilateral involvement accompanied by extensive infiltration of the corneoscleral limbus remains exceptionally rare and poses substantial diagnostic and therapeutic challenges. - Source: PubMed
Publication date: 2026/06/12
Tu YuanyuanSun YakeZhu ManhuiZhao Qingliang - Erdheim-Chester Disease (ECD) constitutes a rare and clinically heterogeneous non-Langerhans cell histiocytosis, characterized by the systemic infiltration of tissues by foamy, lipid-laden histiocytes. These cells typically exhibit an immunophenotypic profile positive for CD68 and negative for CD1a. The disease's multifaceted presentation, which can span from isolated bone lesions to fulminant multi-organ failure, frequently results in considerable diagnostic delay. In this case-based review, we describe the case of a 58-year-old who presented with a primary complaint of exertional dyspnoea and fatigue. The initial diagnostic evaluation revealed a hemodynamically significant circumferential pericardial effusion and imaging findings suggestive of aortitis. Clinical presentation of ECD depends on the organs and tissues involved, and may range from bone pain to neurological symptoms, endocrine dysfunction, and cardiac involvement. Cardiovascular involvement occurs in at least 40% of ECD patients, although it is frequently underdiagnosed. Cardiac ECD is heterogeneous and may mimic many alternative aetiologies. The infiltration of the right atrioventricular sulcus, right atrial walls, or interatrial septum is one of the most typical cardiac manifestations of ECD. Recognition of pseudo-tumour intra-atrial mass, pericardial involvement, as well as the circumferential encasement of the entire aorta, the so-called , are other frequent findings. Diagnosis often requires a multimodal approach, in particular when cardiac symptoms represent the onset of clinical manifestation of ECD. The combined use of computed tomography, fluorodeoxyglucose positron emission tomography, dedicated cardiac and abdominal magnetic resonance imaging, and X-ray of long bones can collectively reveal a constellation of findings diagnostic of ECD. - Source: PubMed
Publication date: 2026/06/15
Di Spigno FrancescoFaggiano AndreaRicchiuto AlfredoTedeschi AndreaBreviario FedericoGerra LuigiTurchio PiergiorgioAschieri DanielaSebastiani Marco - A 7-year-old male patient presented to Jinan Mingshui Eye Hospital (Jinan, China) in June 2025 with a 3-month history of a progressively enlarging mass on the right upper eyelid. The lesion was asymptomatic, with no associated pain, redness or discharge. Physical examination revealed a well-defined, smooth, yellow-red, round mass measuring ~6x5x5 mm at the medial canthus of the right upper eyelid, adjacent to the upper lacrimal punctum. Under general anesthesia, the tumor was completely excised in June 2025. Histopathological examination showed squamous epithelium overlying proliferations of small spindle cells, mitotic figures and scattered Touton-like giant cells. Immunohistochemistry revealed positive staining for CD68, CD163, S-100, CD1a, CD10 and anaplastic lymphoma kinase (ALK), with a Ki-67 proliferation index of ~10%. A diagnosis of ALK-positive epithelioid fibrous histiocytoma (EFH) was established. Postoperative recovery was uneventful, with no recurrence observed during a 6-month follow-up period. This case highlights an unusual presentation of EFH in a pediatric eyelid, where a rare tumor that occurred in the eyelid of a 7-year-old child was accurately diagnosed through a set of immunohistochemical panels containing tissue cell markers (CD68 and CD163), melanoma cell markers (S-100), dendritic cell markers (CD1a), mesenchymal cell markers (CD10) and ALK. - Source: PubMed
Publication date: 2026/06/05
Sun ZhengZhai ZhaoxiaLi YutianShi PeiyanCheng WeiGe JinlingLi Yanfei - Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis that most commonly presents with nodal disease but may involve extranodal sites, including the skin. Purely cutaneous Rosai-Dorfman disease (CRDD) is uncommon and demonstrates a wide range of clinical and histopathologic features, frequently resulting in diagnostic delay. We report a case of a 64-year-old woman with an 18-month history of a progressively enlarging, pruritic nasal mass encompassing the entire nasal dorsum and bilateral nasal sidewalls refractory to multiple therapies and repeatedly misdiagnosed as granulomatous rosacea. Deep biopsy revealed a dense lymphoplasmacytic infiltrate with storiform fibrosis involving the dermis, subcutis, and skeletal muscle. Scattered large histiocytes demonstrated emperipolesis and expressed S100, OCT2, and CD68, whereas CD1a was negative. Extensive ancillary studies excluded infection and hematolymphoid malignancy. This case highlights a rare and underrecognized presentation of CRDD with histopathologically confirmed skeletal muscle involvement and underscores key diagnostic pitfalls relevant to dermatologists and dermatopathologists. - Source: PubMed
Publication date: 2026/06/24
Hamilton LukeBourgeois Julien CJohnson KatherineJimenez AntonioWilson Janice MGoodwin Brandon P