H_89, Dihydrochloride Salt
- Known as:
- H_89, Dihydrochloride Salt
- Catalog number:
- H-5239
- Product Quantity:
- 10 mg
- Category:
- -
- Supplier:
- LCLabs
- Gene target:
- H_89 Dihydrochloride Salt
Related products to: H_89, Dihydrochloride Salt
((Cys31,Nva34)_Neuropeptide Y (27_36))2 Salt _ Binding (Disulfide_bond) Synonym SumFormula C116H186N36O28S2((Cys31,Nva34)_Neuropeptide Y (27_36))2 Salt _ Binding (Disulfide_bond) Synonym SumFormula C116H186N36O28S2(+)-(2S,5R)-1-Allyl-2,5-dimethylpiperazine, (+)-Camphoric Acid Salt C19H34N2O4 CAS: 186094-00-8(+)-(2S,5R)-1-Allyl-2,5-dimethylpiperazine, (+)-Camphoric Acid Salt CAS: 186094-00-8 Formula: C19H34N2O4(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt C17H20N3NaO4S CAS: 102418-74-6(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt CAS: 102418-74-6 Formula: C17H20N3NaO4S(+)-Tianeptine Monosodium Salt C21H24ClN2NaO4S CAS: 169293-32-7(+)-Tianeptine Monosodium Salt CAS: 169293-32-7 Formula: C21H24ClN2NaO4S(+)_3_Bromocamphor_8_sulfonic acid ammonium Salt(+)_Dipara tolouyl_d_tartaric acid salt of 4_(+)_Emetine dihydrochloride hydrate(+)_Usnic acid sodium salt Usnic acid sodium salt(+__)_3_Methyl_2_oxovaleric acid Sodium salt(-)-Tianeptine Monosodium Salt C21H24ClN2NaO4S CAS:(-)-Tianeptine Monosodium Salt CAS: Formula: C21H24ClN2NaO4S Related articles to: H_89, Dihydrochloride Salt
- Breast cancer (BC) is a biologically heterogeneous disease, and no single imaging modality captures the full spectrum of phenotypes across all stages of the disease. This review summarizes advances in receptor-targeted nuclear imaging approaches that support patient stratification, treatment selection and response monitoring. - Source: PubMed
Publication date: 2026/04/26
Paraïso Pvan Deurzen C H MSeimbille Y - - Source: PubMed
Publication date: 2026/04/24
Gould Poppy APetukhova Lynn - In drug discovery tasks, achieving a balance between high biological activity toward therapeutic targets and synthetic chemical feasibility is critically important. While the recently proposed deep learning-based molecular generation models have enabled explorations of vast chemical spaces, most existing approaches do not consider synthetic routes for generated compounds. To address this issue, TRACE-GFN is proposed for molecular optimization; this method incorporates chemical reaction pathways into a quantitative structure-activity relationship (QSAR)-guided molecular design procedure. The method integrates a transformer model to explicitly learn chemical reactions with a generative flow network (GFlowNet) that efficiently samples diverse candidates. In benchmark experiments involving dopamine receptor D2 (DRD2), AKT serine/threonine kinase 1 (AKT1), and C-X-C motif chemokine receptor 4 (CXCR4), TRACE-GFN demonstrated the ability to identify compounds with high QSAR values while maintaining strong diversity, outperforming the existing molecular generation models. These results demonstrate that the proposed model can efficiently explore promising compounds while accounting for real-world chemical reactions. The source code is publicly available under an MIT license at https://github.com/sekijima-lab/TRACE-GFN. - Source: PubMed
Publication date: 2026/04/25
Nakamura ShogoYasuo NobuakiSekijima Masakazu - To study corneal homeostasis, corneal fibroblasts were cultured for 24 and 72 h on a corneal lens in the presence of conditioned media from cells of healthy cornea (keratocytes and limbal MSCs) or fibrous cornea (myofibroblasts). Conditioned media from keratocytes and limbal MSCs induced changes in fibroblast morphology, increased cell necrosis throughout the observation period (72 h), reduced proliferative activity and the number of CXCR4 corneal fibroblasts, and induced opposite shifts in the level of SDF-1 secretion. The conditioned medium of myofibroblasts increased the number of Ki-67 and CXCR4 fibroblasts after 24 h and cell apoptosis after 72 observations; it also decreased SDF-1 production by fibroblasts. Our data demonstrate that regulation of CXCR4 receptor expression on corneal fibroblasts by the total soluble secretome plays an important role in maintaining corneal homeostasis. - Source: PubMed
Publication date: 2026/04/24
Surovtseva M AKim I IButikova E AGaivoronskaya A AChepeleva E VIskakov I ATrunov A NChernykh V VPoveshchenko O V - - Source: PubMed
Publication date: 2026/04/23
Kuppens AmandineRogister BernardNeirinckx Virginie