TRIM22 antibody - N-terminal region (P100888_P050)
- Known as:
- TRIM22 (anti-) - N-terminal region (P100888_P050)
- Catalog number:
- p100888_p050
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Aviva Systems Biology
- Gene target:
- TRIM22 antibody - N-terminal region (P100888_P050)
Related genes to: TRIM22 antibody - N-terminal region (P100888_P050)
- Gene:
- TRIM22 NIH gene
- Name:
- tripartite motif containing 22
- Previous symbol:
- -
- Synonyms:
- STAF50, GPSTAF50, RNF94
- Chromosome:
- 11p15.4
- Locus Type:
- gene with protein product
- Date approved:
- 2001-08-10
- Date modifiied:
- 2016-10-05
Related products to: TRIM22 antibody - N-terminal region (P100888_P050)
Related articles to: TRIM22 antibody - N-terminal region (P100888_P050)
- Liver cirrhosis(LC) represents the end stage of chronic liver disease, yet reliable molecular markers remain limited. This study aimed to uncover potential diagnostic biomarkers and therapeutic targets for LC. - Source: PubMed
Publication date: 2026/03/14
Zhang KangChen TingJia ZhangyuZhao JunxiaHuang Na - - Source: PubMed
Publication date: 2026/02/28
Liu JinghongZhang JianboChen QunxiangQing WeijiaPeng YongchunHe ZhijingZhou XiPi HuifengLi BoLin QingyunLiu JunxinZhang FanZhang ShengFan Tengfei - Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus and a major cause of renal dysfunction, while reliable non-invasive biomarkers remain limited. Transcriptomic data from three LN cohorts were analyzed to identify differentially expressed genes (DEGs). Immune-associated DEGs were selected using WGCNA and prioritized via multiple machine learning algorithms. Diagnostic performance was evaluated with ROC curves and nomogram modeling, accompanied by functional enrichment and immune infiltration analyses. Independent validation was performed by qRT-PCR in peripheral blood samples from 13 LN patients and 10 healthy controls. A total of 320 DEGs were identified, including 53 linked to immune processes. In the transcriptomic datasets, four candidate hub genes (,,,) were initially identified. Furthermore, immune infiltration analysis suggested gene-specific immune interaction patterns, particularly associating with CD4⁺ T-cell–related signatures. qRT-PCR confirmed upregulation of and , while and showed no significant elevation. Accordingly, a refined two-gene signature was constructed, showing consistent discriminatory trends in the training dataset and the clinical validation cohort (AUCs > 0.9). and were consistently upregulated in the peripheral blood of patients with lupus nephritis and may represent potential immune-related biomarkers. - Source: PubMed
Publication date: 2026/02/20
Deng JiayiZhang ZimiaoLai YueyuanChen JinpengMa XiaomeiGao ZhenkaiLin ChaoLi XiaohongWu WeihaoChen CongjieShangguan XiaohuiHuang YanhongQiu HaoranQiu XiaomingChen Longtian - Diabetic nephropathy (DN) is a major cause of end-stage renal disease. Understanding the molecular mechanisms underlying DN is crucial for developing new therapeutic targets and diagnostic biomarkers. - Source: PubMed
Publication date: 2026/02/04
Yu DanFeng ZhipengYao HuanAn Ke - Colorectal cancer (CRC) is one of the most common causes of cancer-associated death worldwide, and a rapid increase in the incidence and mortality of CRC has been predicted with a marked trend in the younger age group. Therefore, identifying novel therapeutic targets and developing effective therapies for CRC treatment is needed. Tripartite motif 22 (TRIM22) has been implicated in several cancers; however, its role in CRC therapy remains unknown. - Source: PubMed
Publication date: 2026/02/11
Ma XiaoxuanRuddarraju Radhakrishnam RajuLi YibingShen BingyanLiu HaizhenGe ChaochaoPeng NaixinGao LeiWang ChaojieZhang GuoyuDai FujunLv Xinrui