ETV6 antibody - N-terminal region (P100806_P050)
- Known as:
- ETV6 (anti-) - N-terminal region (P100806_P050)
- Catalog number:
- p100806_p050
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Aviva Systems Biology
- Gene target:
- ETV6 antibody - N-terminal region (P100806_P050)
Related genes to: ETV6 antibody - N-terminal region (P100806_P050)
- Gene:
- ETV6 NIH gene
- Name:
- ETS variant 6
- Previous symbol:
- -
- Synonyms:
- TEL
- Chromosome:
- 12p13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1995-11-28
- Date modifiied:
- 2019-04-23
Related products to: ETV6 antibody - N-terminal region (P100806_P050)
Related articles to: ETV6 antibody - N-terminal region (P100806_P050)
- ETV6::RUNX1 is the most common genetic abnormality in pediatric B-cell acute lymphoblastic leukemia (ALL; ∼25%), yet the comprehensive genetic architecture and molecular predictors of intermediate-risk (IR) stratification remain incompletely characterized. - Source: PubMed
Publication date: 2026/09/10
Luo HualeiZhou GuichiLi QianYao QiangChen YunshengTang XueLiu ShilinYe HuiyingMai HuirongFu XiaoyingWang Ying - - Source: PubMed
Publication date: 2025/11/07
Gupta ParasRathore ShwetaThakur VenusSharma PraveenMallik NabhajitJain ArihantSuri VikasNaseem ShanoMalhotra PankajSreedharanunni Sreejesh - We present a case of a 14-year-old male who presented with loss of appetite, nosebleeds, and fatigue. He visited the clinic, and bone marrow studies were suggested. Bone marrow, core biopsy and clot section showed hypercellularity (80-90%) with sheets of blasts with suspicion of precursor B acute lymphoblastic leukemia (B-ALL). Chromosome analysis of 20 trypsin-Giemsa banded metaphase spreads showed an abnormal male composite karyotype described as 45~47,XY,+1,add(1)(p13),add(1)(q10),add(7)(q36), add(12)(q24.1),der(12)(p13->q24.1::12p13.2->12p13.1::12q24.1->12qter),-13,-15,add(16)(p13.1),-17,+1~3 mar[cp17]/46,XY[3]. Fluorescence in situ hybridization (FISH) was performed, showing one diminished signal for ETV6 in 99% [198/200] of the nuclei examined with the ETV6/RUNX1 probe. ETV6 break-apart probe on interphase nuclei showed one fusion (normal) and one green signal (5'ETV6) in 92% [184/200] of the nuclei. Metaphase FISH with the ETV6 BA probe showed one fusion on the normal chromosome 12 and one green signal (5'ETV6) on the long arm of the derivative chromosome 12. Additionally, metaphase FISH showed a 1q25 signal (green) in one abnormal copy of chromosome 1 as well as 1p36 signal (orange) in the additional abnormal copy of chromosome 1, and a retinoblastoma (Rb) signal (13q14.2) on the derivative chromosome 7. In light of these studies, the karyotype was described as a highly complex karyotype associated with genomic instability and a poor prognosis. - Source: PubMed
Chau DoriOentoro JaymieRocha JacobGiordano ChristinaAhmed TahmeenaTirado Carlos A - Neurotrophic tropomyosin receptor kinase () fusion is one of the druggable driver genes of thyroid cancer, which is confirmed in surgical specimens. However, there is a risk that certain fusion patterns may not be detected using gene panel testing. This study aimed to identify patients harboring fusion who might be overlooked by panel testing. - Source: PubMed
Toda SojiKasajima RikaOkubo YoichiroSaito NaoKadoya MeiMatsui A ISato ShinyaYamazaki HaruhikoSuganuma NobuyasuMasudo KatsuhikoSaito AyaHoshino Daisuke - Acute lymphoblastic leukemia (ALL) is the most common pediatric hematologic malignancy, with the majority of cases being of B-cell origin. While many patients respond favorably to therapy, a subset experiences early relapse or poor outcomes, underscoring the critical need for reliable prognostic biomarkers. This study investigated the significance of CD123 expression in diagnosing the disease, evaluating therapeutic efficacy, and predicting prognosis in pediatric B-cell ALL (B-ALL). - Source: PubMed
Publication date: 2026/08/12
Li ZhengChen QinfaZhou ZhiyongHe Fei