ZNF423 antibody - middle region (ARP39167_P050)
- Known as:
- ZNF423 (anti-) - middle region (ARP39167_P050)
- Catalog number:
- arp39167_p050
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Aviva Systems Biology
- Gene target:
- ZNF423 antibody - middle region (ARP39167_P050)
Related genes to: ZNF423 antibody - middle region (ARP39167_P050)
- Gene:
- ZNF423 NIH gene
- Name:
- zinc finger protein 423
- Previous symbol:
- -
- Synonyms:
- KIAA0760, OAZ, hOAZ, Ebfaz, Zfp104, NPHP14, JBTS19
- Chromosome:
- 16q12.1
- Locus Type:
- gene with protein product
- Date approved:
- 2004-04-06
- Date modifiied:
- 2018-04-17
Related products to: ZNF423 antibody - middle region (ARP39167_P050)
Related articles to: ZNF423 antibody - middle region (ARP39167_P050)
- This study investigated the effects of vitamin A (VA) injection on growth performance, muscle development, and skeletal muscle transcriptomics in calves during the cow-calf phase. Pregnant cows at 250 days of gestation were randomly assigned to one of three treatments: control (CON; no VA injection), VA injection in cows at 250 d of gestation (VAcow), or VA injections in calves at birth and 60 days of age (VAcalf). Calves were weighed at 60 d and weaning. Carcass ultrasound and muscle biopsy were conducted at weaning. Gene expressions were analyzed by RT-qPCR. Male calves in the VAcow group had higher (P = 0.01) ADG than Control males and VA-treated females. Weaning BW was greater (P < 0.01) in VAcalf and VAcow males compared to Control males and VA-treated females. Gene expression analysis revealed that RARA, MYF5, CEBPA, and DLK1 were higher (P ≤ 0.05) expressed in Control and VAcow calves than in VAcalf calves. Expressions of ZNF423 and RXRA tended to be greater (P ≤ 0.09) in VAcow males than in VAcalf males and VA-treated females. The expression of PAX7 was higher (P < 0.01) in VAcow males than in all other groups. Also, IGFR1 expression tended to be greater (P = 0.07) in VAcow males than in Control and VAcalf males and VAcalf females. In conclusion, VA injection during late gestation or early postnatal life improved growth of male calves. Maternal VA injection had a more pronounced effect on muscle gene expression, particularly in male calves. - Source: PubMed
Publication date: 2026/03/14
Oliveira J MCasagrande D RLaura S A SHorta A H AMiranda A SGionbelli T R SChalfun L H LLadeira M M - Gastric cancer (GC) is the fifth most common type worldwide, representing a public health problem. Among the genes related to this tumorigenesis, the family of matrix metalloproteinases (MMPs), essential regulators of the extracellular matrix (ECM), stand out for their involvement in the development and progression of GC. Therefore, we aimed to evaluate MMP gene expression variation, its relationship with clinicopathological factors and its transcriptome-wide associations. To this end, RNAseq, correlation network, and biological pathway enrichment analyses were performed on tumor samples from GC and peritumoral samples from patients treated at a reference center in the Northern region of Brazil. Among the 22 investigated MMPs, seven genes (MMP2, MMP3, MMP10, MMP12, MMP14, MMP15, and MMP16) were upregulated in cancer, while MMP8 was downregulated. Increased expression of seven of the eight differentially expressed MMPs was found in early stages of the disease compared to Tumor, Node, Metastasis (TNM) stage IV. MMP16 showed higher expression in the diffuse-type gastric adenocarcinoma. An increased expression of MMP10 was observed in the EBV/TCGA group. A significant reduction in survival was noticed in those patients with lower expression of MMP8, MMP12, and MMP14. Transcriptomic correlation analyses demonstrated that differentially expressed MMPs interact with genes likely involved in cell adhesion, ECM organization, and immune response, such as COL1A2, CDH11, KIRREL1, PPP1R14D, CEACAM8, ZNF423, and PRRX1. The enrichment of biological pathways suggests involvement in processes such as ECM organization, collagen and proteoglycan degradation, suggesting that these genes possibly are involved in carcinogenic dynamics, supporting the role of MMPs in tumor ECM reorganization. - Source: PubMed
Publication date: 2026/02/23
Bastos Aline CostaKhayat André SalimMoraes Emanuele Raimunda LouzadaTavares Ágatha Tereza MirandaMourão Ronald Matheus da SilvaMoreira Fabiano CordeiroCasseb Samir Mansour MoraesDemachki SamiaIshak GeraldoBarra Williams FernandesBurbano Rommel Mario Rodríguezde Assumpção Paulo Pimentel
- Source: PubMed
- White adipose tissue (WAT) expansion occurs through generation of new adipocytes from adipose progenitor cells (APC). The objective of this study was to characterize and validate a new transcriptional profile of APC. - Source: PubMed
Publication date: 2026/02/03
Whytock Katie LDivoux AdelineGunsch GilianNie JiaKanshana Jitendra SBasantani Mahesh KRoss Zana MPino Maria FGlass CarleyMusi NicholasKershaw Erin ETownsend KristySmith Steven RSparks Lauren M - Congenital diaphragmatic hernia (CDH) is a developmental anomaly associated with high mortality and morbidity, primarily attributed to accompanying pulmonary hypoplasia. Genetic factors are crucial in the etiology and pathogenesis of CDH, with various copy number variations (CNVs) and gene sequence variants implicated in this malformation. Previous studies have underscored the importance of retinoic acid (RA) signaling pathways and related genes. Nonetheless, the complexity of diaphragmatic development involving cell migration, cytoskeleton organization, and myogenesis suggests that candidate CDH genes extend beyond the RA pathway. To explore novel candidate gene variants and their roles in CDH, we performed whole exome sequencing (WES) in CDH-affected fetuses. - Source: PubMed
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